Abstract: Delta-like non-canonical Notch ligand 1 (DLK1) inhibitors are disclosed. The DLK1 inhibitors can be used to treat cancers such as myelodysplastic syndrome (MDS), and cancers of the liver, breast, brain, pancreas, colon, lung, kidney, ovary, testes, and/or adrenal gland, among other uses described herein.

Abstract: A glassy, particulate, melt extrusion encapsulation composition and a process of making the composition are described. The encapsulation composition is highly soluble in aqueous systems, has a low level of encapsulate on the surface of the particles, and has a narrow particle size and shape distribution. Food systems containing the encapsulation composition are also described.

Abstract: A glassy extrusion encapsulation composition and a method of making the composition are provided. The encapsulation composition comprises an encapsulate encapsulated in a glassy matrix comprising 0.5 to 12% by weight, based on the total weight of the glassy matrix, of at least one surface active plant extract, and 88 to 99.5% of at least one carbohydrate. The addition of a surface active plant extract to a carbohydrate matrix markedly increases the load of an encapsulate in the encapsulation composition. Such glassy matrices are useful for encapsulation of encapsulates, for example, flavors and medications. A food composition containing the encapsulation composition is also provided.

Abstract: A dense solid particulate encapsulation compositions comprising above 40% and up to 100% spices, herbs, fruit and vegetable powders in the encapsulating matrix are disclosed. The encapsulation of encapsulants including flavors, fragrances, medications, nutritional supplements, and vitamins, all in the range from 0.1% to 20% by weight of the encapsulation composition is described. Also disclosed is the process of making of the encapsulation compositions. The target applications of the encapsulated compositions are also described.

Abstract: A glassy extrusion encapsulation composition and a method of making the composition are provided. The encapsulation composition comprises an encapsulate encapsulated in a glassy matrix comprising 0.5 to 12% by weight, based on the total weight of the glassy matrix, of at least one surface active plant extract, and 88 to 99.5% of at least one carbohydrate. The addition of a surface active plant extract to a carbohydrate matrix markedly increases the load of an encapsulate in the encapsulation composition. Such glassy matrices are useful for encapsulation of encapsulates, for example, flavors and medications. A food composition containing the encapsulation composition is also provided.

Abstract: A portable, temperature controlled food storage compartment. The compartment includes a base having an internal cavity including a temperature controlling element for controlling the temperature of food stored in the compartment, and a detachable cover including a number of side panels, a front panel and a top panel. Each of the number of side panels is pivotally connected to the top panel. The front panel is pivotally connected to the number of side panels. The cover is configurable in a food storage position in which a lower edge portion of each of the number of side panels is coupled to the base to form an interior volume at least partially defined by the base and the cover and for storing food. The cover is configurable in a collapsed position in which at least one surface portion of at least one of the number of side panels and the top panel contacts the base.

Abstract: A method and system for managing ad campaign data. According to one embodiment, an application receives a request to store data associated with an ad campaign, and responsive to the request, stores one or more output files and context information associated with the data, the context information assembled according to a pre-defined data format defining a role of the data within the ad campaign.