Patents by Inventor Suzanne M. J. Fleiszig

Suzanne M. J. Fleiszig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-microbial peptides and methods of use thereof
    Patent number: 9545461
    Abstract: The present disclosure provides antimicrobial peptides, and compositions comprising same. The present disclosure further provides methods of inhibiting microbial growth.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: January 17, 2017
    Assignee: The Regents of the University of California
    Inventors: Suzanne M. J. Fleiszig, David J. Evans, Kwai Ping Tam, James J. Mun
  • ANTI-MICROBIAL PEPTIDES AND METHODS OF USE THEREOF
    Publication number: 20160151534
    Abstract: The present disclosure provides antimicrobial peptides, and compositions comprising same. The present disclosure further provides methods of inhibiting microbial growth.
    Type: Application
    Filed: October 21, 2015
    Publication date: June 2, 2016
    Inventors: Suzanne M.J. Fleiszig, David J. Evans, Kwai Ping Tam, James J. Mun
  • Anti-microbial peptides and methods of use thereof
    Patent number: 9187541
    Abstract: The present disclosure provides antimicrobial peptides, and compositions comprising same. The present disclosure further provides methods of inhibiting microbial growth.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: November 17, 2015
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Suzanne M. J. Fleiszig, David J. Evans, Kwai Ping Tam, James J. Mun
  • Anti-Microbial Peptides and Methods of Use Thereof
    Publication number: 20140221273
    Abstract: The present disclosure provides antimicrobial peptides, and compositions comprising same. The present disclosure further provides methods of inhibiting microbial growth.
    Type: Application
    Filed: April 16, 2012
    Publication date: August 7, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Suzanne M.J. Fleiszig, David J. Evans, Kwai Ping Tam, James J. Mun
  • Methods and compositions for treating ocular disease
    Publication number: 20100267645
    Abstract: The use of collectins and/or surfactant proteins for the treatment and prevention of ocular disease.
    Type: Application
    Filed: December 20, 2007
    Publication date: October 21, 2010
    Applicants: The Research Foundation of State University of New York, The Regents of the University of California
    Inventors: Suzanne M.J. Fleiszig, David J. Evans, Robert A. Sack
  • Use of lipopolysaccharides to manage corneal infections and wounds
    Patent number: 6984622
    Abstract: The antibiotic polypeptide ?-defensin-2 (hBD-2) is expressed in the eye, and is useful for treating ocular wounds. hBD-2 is increased in the eye upon exposure to lipopolysaccharides (LPS). Administration of LPS to the eye thereby provides a useful method for increasing the amount of this antibiotic peptide in the eye.
    Type: Grant
    Filed: April 10, 2002
    Date of Patent: January 10, 2006
    Assignee: The Regents of the University of California
    Inventors: Suzanne M. J. Fleiszig, Nancy A. McNamara
  • Methods and compositions for treating ocular disease
    Publication number: 20040229802
    Abstract: The use of collectins and/or surfactant proteins for the treatment and prevention of ocular disease.
    Type: Application
    Filed: April 14, 2004
    Publication date: November 18, 2004
    Inventors: Suzanne M.J. Fleiszig, David J. Evans, Robert A. Sack
  • Use of antibiotic peptides produced by human corneal epithelial cells to manage infection
    Publication number: 20020110553
    Abstract: The antibiotic polypeptide &bgr;-defensin-2 (hBD-2) is expressed in the eye, and is useful for treating ocular wounds. hBD-2 may be administered to the eye, or its endogenous expression may be upregulated by administering an hBD-2 stimulating compound.
    Type: Application
    Filed: April 10, 2002
    Publication date: August 15, 2002
    Applicant: The Regents of the University of California
    Inventors: Suzanne M.J. Fleiszig, Nancy A. McNamara
  • Methods for inhibiting bacterial cytotoxicity
    Patent number: 5948815
    Abstract: The invention provides methods and compositions for reducing microbial cytotoxicity to a cell, by contacting a cell subject to extracellular microbial cytotoxicity with an effective amount of at least one of genistein or a genistein derivative. In preferred embodiments, the microbe is a gram-negative bacterium, a non-Enterobacteriaceae or a Pseudomonas aeruginosa or cepacia and the host cell is a mammalian epithelial cell, especially a lung epithelial cell or a corneal epithelial cell. The genistein or genistein derivative may be administered prophylactically prior to infection, subsequent thereto and/or in conjunction with conventional antibiotic therapies.
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: September 7, 1999
    Assignee: The Regents of the University of California
    Inventors: Suzanne M. J. Fleiszig, David J. Evans