Patents by Inventor Suzy V. Torti

Suzy V. Torti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic and prognostic markers for cancer
    Patent number: 10473662
    Abstract: Compositions and methods useful for diagnosis and prognosis of cancer are provided. More particularly, methods for detecting breast or prostate cancer protein or nucleic acid biomarkers consisting of iron homeostasis biomarkers in a biological sample obtained from a subject are provided.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: November 12, 2019
    Assignee: WAKE FOREST UNIVERSITY HEALTH SCIENCES
    Inventors: Frank M. Torti, Suzy V. Torti, Lance Miller
  • METHODS OF TREATING CANCEROUS TISSUE
    Publication number: 20180153616
    Abstract: In one aspect, methods of treating cancerous tissue are described herein. In some embodiments, a method of treating cancerous tissue comprises inducing necrotic cell death in cancer stem cells in vivo during hyperthermic treatment of the tissue, wherein inducing necrotic cell death comprises positioning nanoparticles adjacent to the cancer stem cells and irradiating the nanoparticles with electromagnetic radiation resulting in membrane damage to the cancer stem cells.
    Type: Application
    Filed: November 16, 2017
    Publication date: June 7, 2018
    Inventors: Suzy V. Torti, Frank M. Torti, Andrew Ryan Burke, Ravi Nandan-Singh
  • DIAGNOSTIC AND PROGNOSTIC MARKERS FOR CANCER
    Publication number: 20170082629
    Abstract: Compositions and methods useful for diagnosis and prognosis of cancer are provided.
    Type: Application
    Filed: September 21, 2016
    Publication date: March 23, 2017
    Inventors: Frank M. Torti, Suzy V. Torti, Lance Miller
  • Diagnostic and Prognostic Markers for Cancer
    Publication number: 20140296098
    Abstract: Compositions and methods useful for diagnosis and prognosis of cancer are provided.
    Type: Application
    Filed: April 10, 2014
    Publication date: October 2, 2014
    Inventors: Frank M. Torti, Suzy V. Torti, Lance D. Miller
  • METHODS OF TREATING CANCEROUS TISSUE
    Publication number: 20130304050
    Abstract: In one aspect, methods of treating cancerous tissue are described herein. In some embodiments, a method of treating cancerous tissue comprises inducing necrotic cell death in cancer stem cells in vivo during hyperthermic treatment of the tissue, wherein inducing necrotic cell death comprises positioning nanoparticles adjacent to the cancer stem cells and irradiating the nanoparticles with electromagnetic radiation resulting in membrane damage to the cancer stem cells.
    Type: Application
    Filed: March 15, 2013
    Publication date: November 14, 2013
    Inventors: Suzy V. Torti, Frank M. Torti, Andrew Ryan Burke, Ravi Nandan-Singh
  • Diagnostic and Prognostic Markers for Cancer
    Publication number: 20130012409
    Abstract: Compositions and methods useful for diagnosis and prognosis of cancer are provided.
    Type: Application
    Filed: August 10, 2012
    Publication date: January 10, 2013
    Inventors: Frank M., Suzy V. Torti, Lance Miller
  • Diagnostic and Prognostic Markers for Cancer
    Publication number: 20120309640
    Abstract: Compositions and methods useful for diagnosis and prognosis of cancer are provided.
    Type: Application
    Filed: October 8, 2010
    Publication date: December 6, 2012
    Inventors: Frank M. Torti, Suzy V. Torti, Lance D. Miller
  • Cytotoxic metal chelators and methods for making and using same
    Patent number: 6589966
    Abstract: A family of hexadentate Fe(II) chelators having marked antiproliferative activity against tumor cells is disclosed.
    Type: Grant
    Filed: September 18, 2000
    Date of Patent: July 8, 2003
    Assignees: Wake Forest University Health Sciences, University of New Hampshile, National Institutes of Health
    Inventors: Suzy V. Torti, Frank M. Torti, Roy P. Planalp, Martin W. Brechbiel
  • Five member ring sulfenate esters and thiosulfinate esters
    Patent number: 6242478
    Abstract: Disclosed are novel sulfenate esters and thiosulfinate esters that induce the expression of metabolic enzymes, particularly Phase II enzymes such as glutathione-s-transferase, DT-diaphorase and Ferritin H when administered to a subject. Also disclosed, such compounds are effective to displace a zinc ion from retroviral zinc finger nucleocapsid proteins effective to inhibit HIV replication. The present invention is further directed to novel methods of making these compounds, and any compounds produced by the process of making these novel compounds.
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: June 5, 2001
    Assignee: Wake Forest University
    Inventors: Mark E. Welker, Suzy V. Torti, Frank M. Torti, Alan J. Townsend, Eva Pietsch, Allison L. Hurley