Patents by Inventor Sveinbjorn Gizurarson

Sveinbjorn Gizurarson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200197494
    Abstract: Provided herein are pharmaceutical compositions containing a therapeutic agent, an alkylglycoside, and pharmaceutically acceptable excipients and use of such compositions in the treatment of various conditions.
    Type: Application
    Filed: May 25, 2018
    Publication date: June 25, 2020
    Inventors: Olivier Laurent, Joel F. Martin, Sveinbjorn Gizurarson
  • Publication number: 20190209511
    Abstract: A formulation to be used for administering a therapeutically effective amount of an antimicrobiologically active monoglyceride to a mammal including administering a pharmaceutical composition having a total volume of 1-5000 ?L to a surface of the mammal such as the nasal, ocular, otal, pharynx, larynx, sinuses, oral cavity, vaginal or dermal surface, the pharmaceutical composition including the therapeutically effective amount of the antimicrobiologically active monoglyceride dissolved or suspended in a volume of 1-5000 ?L of an methoxypolyethylene glycol referred to as mPEG and polyoxyethylene glycol (PEG)-fatty acid mono- or diglyceride so that upon administration of the pharmaceutical composition to the surface the formulation expresses thermostability within the range from below zero degrees C. to above 35-40° C. and thereby allows the antimicrobiologically active monoglyceride to exert its therapeutic effect.
    Type: Application
    Filed: June 19, 2017
    Publication date: July 11, 2019
    Inventors: Sveinbjorn GIZURARSON, Helga HELGADOTTIR, Thordis KRISTMUNDSDOTTIR
  • Publication number: 20190209510
    Abstract: This invention relates to novel synergy, where the antimicrobial effects of microbicidal lipids are augmented with minor amounts of ethanol, in particular to augment the microbicidal effects for preventing infection in the nasal, ocular, otal, pharynx, larynx, sinuses, oral cavity, vaginal or dermal surface of a mammal by virus, pathogenic bacteria or fungi.
    Type: Application
    Filed: June 19, 2017
    Publication date: July 11, 2019
    Inventors: Sveinbjorn GIZURARSON, Helga HELGADOTTIR, Thordis KRISTMUNDSDOTTIR, Halldor THORMAR, Sigurdur GUDMUNDSSON
  • Publication number: 20190000862
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Application
    Filed: July 20, 2018
    Publication date: January 3, 2019
    Inventor: Sveinbjorn Gizurarson
  • Patent number: 10052333
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: August 21, 2018
    Assignee: UNIVERSITY OF ICELAND
    Inventor: Sveinbjorn Gizurarson
  • Patent number: 9968648
    Abstract: The invention relates to the use of a mixture of tetraethyleneglycol and amino sugars such as glucosamine or galactosamine to protect peptides and proteins and enhance their stability in solution.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: May 15, 2018
    Assignee: Calor ehf.
    Inventors: Sveinbjorn Gizurarson, Stefan Jon Sigurdsson
  • Publication number: 20180000834
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Application
    Filed: May 25, 2017
    Publication date: January 4, 2018
    Inventor: Sveinbjorn Gizurarson
  • Patent number: 9687495
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: June 27, 2017
    Assignees: HANANJA EHF, UNIVERSITY OF ICELAND
    Inventor: Sveinbjorn Gizurarson
  • Publication number: 20170157201
    Abstract: The invention relates to the use of a mixture of tetraethyleneglycol and aminosugars such as glucosamine or galactosamine to protect peptides and proteins and enhance their stabilityin solution.
    Type: Application
    Filed: May 15, 2015
    Publication date: June 8, 2017
    Inventors: Sveinbjorn GIZURARSON, Stefan SIGURDSSON
  • Publication number: 20160158248
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Application
    Filed: February 10, 2016
    Publication date: June 9, 2016
    Inventor: Sveinbjorn Gizurarson
  • Patent number: 9289432
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Grant
    Filed: July 14, 2014
    Date of Patent: March 22, 2016
    Assignee: HANANJA EHF and UNIVERSITY OF ICELAND
    Inventor: Sveinbjorn Gizurarson
  • Patent number: 9168284
    Abstract: The present invention relates to the biological and pharmacological effects of placental protein 13 (PP-13), an effect that may be used as a treatment and/or prevention of preeclampsia and placental insufficiencies, in pregnant female mammals, especially pregnant women. The invention relates to a method to treat female mammals with the purpose to precondition the uterine arteries and prevent and/or reverse the pathological conditions associated with placental insufficiency such as preeclampsia, HELLP and/or eclampsia.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: October 27, 2015
    Inventors: Sveinbjorn Gizurarson, Hamutal Meiri
  • Publication number: 20140323472
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Application
    Filed: July 14, 2014
    Publication date: October 30, 2014
    Inventor: Sveinbjorn Gizurarson
  • Patent number: 8809322
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: August 19, 2014
    Assignees: Hananja EHF, University of Iceland
    Inventor: Sveinbjorn Gizurarson
  • Publication number: 20140031274
    Abstract: The present invention relates to the biological and pharmacological effects of placental protein 13 (PP-13), an effect that may be used as a treatment and/or prevention of preeclampsia and placental insufficiencies, in pregnant female mammals, especially pregnant women. The invention relates to a method to treat female mammals with the purpose to precondition the uterine arteries and prevent and/or reverse the pathological conditions associated with placental insufficiency such as preeclampsia, HELLP and/or eclampsia.
    Type: Application
    Filed: December 14, 2011
    Publication date: January 30, 2014
    Applicants: UNIVERSITY OF ICELAND, HANANJA EHF
    Inventors: Sveinbjorn Gizurarson, Hamutal Meiri
  • Publication number: 20120264745
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Application
    Filed: April 13, 2012
    Publication date: October 18, 2012
    Applicants: University of Iceland, Hananja ehf
    Inventors: Sveinbjorn Gizurarson, James Arp, Raouf Ghaderi, Michael E. Lusty, Gregory G. Plucinski, Mehdi Yazdi
  • Patent number: 8217033
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Grant
    Filed: May 20, 2009
    Date of Patent: July 10, 2012
    Assignees: Hananja EHF, University of Iceland
    Inventor: Sveinbjorn Gizurarson
  • Publication number: 20090227568
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Application
    Filed: May 20, 2009
    Publication date: September 10, 2009
    Inventor: Sveinbjorn Gizurarson
  • Publication number: 20080275030
    Abstract: The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration. The invention also provides methods of administering such compositions to a mammal.
    Type: Application
    Filed: January 18, 2008
    Publication date: November 6, 2008
    Inventors: Sveinbjorn Gizurarson, James Arp, Raouf Ghaderi, Michael E. Lusty, Gregory G. Plucinski, Mehdi Yazdi
  • Publication number: 20050163787
    Abstract: A pharmaceutical composition to be administered to mammals via the mucosal route consisting of a vehicle system comprising mono-/dietherglycerides conjugated with a water soluble polymer groups selected from PEG's containing 2-30 polyoxyethylene units, an antigen and optionally a bacterial toxin for the augmentation of immune responses for vaccination, immunisation, treatment of allergy, treatment of cancer, treatment of infectious disease, treatment of an autoimmune disease, Alzheimer's, substance addiction or the treatment of a disease which is fully or partially controlled by the body immune system.
    Type: Application
    Filed: February 10, 2003
    Publication date: July 28, 2005
    Applicant: LYFJATHROUN HF, BIOPHARMACEUTICAL
    Inventors: Sveinbjorn Gizurarson, Sigriour Olafsdottir