Patents by Inventor Sven E. H. Hernestam

Sven E. H. Hernestam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4894221
    Abstract: Novel morpholino compounds having the general formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R.sub.2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, the sum of the carbon atoms in the groups R.sub.1 and R.sub.2 being at least 10 and preferably 10 to 20; and pharmaceutically acceptable salts thereof. Compositions for the treatment of the oral cavity and especially the tooth surfaces containing the novel compound or a salt thereof, preferably from 0.1 to 5% by weight thereof. Use of the compounds to inhibit the formation of dental plaque or remove plaque already formed by application of the compound in an aqueous solution or a composition to the surfaces of the oral cavity, especially the surfaces of the teeth. Processes for the preparation of the compounds.
    Type: Grant
    Filed: March 30, 1983
    Date of Patent: January 16, 1990
    Assignee: AB Ferrosan
    Inventors: Sven E. H. Hernestam, Nils A. Nilsson, Willard Lars-Olof
  • Patent number: 4636382
    Abstract: Novel morpholino compounds having the general formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R.sub.2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, the sum of the carbon atoms in the groups R.sub.1 and R.sub.2 being at least 10 and preferably 10 to 20; and pharmaceutically acceptable salts thereof. Compositions for the treatment of the oral cavity and especially the tooth surfaces containing the novel compound or a salt thereof, preferably from 0.1 to 5% by weight thereof. Use of the compounds to inhibit the formation of dental plaque or remove plaque already formed by application of the compound in an aqueous solution or a composition to the surfaces of the oral cavity, especially the surfaces of the teeth. Processes for the preparation of the compounds.
    Type: Grant
    Filed: February 14, 1985
    Date of Patent: January 13, 1987
    Assignee: AB Ferrosan
    Inventors: Sven E. H. Hernestam, Nils A. Nilsson, Lars-Olof Willard
  • Patent number: 4344952
    Abstract: A method of treating diarrhoea and promoting weight gain in mammals by administration of an effective amount of a compound selected from the group consisting of 4-fluoro-.gamma.-(4-alkylpiperidino)-butyrophenone of the formula ##STR1## wherein R is lower alkyl having 1 to 6 carbon atoms, or pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: May 30, 1980
    Date of Patent: August 17, 1982
    Assignee: AB Ferrosan
    Inventors: Sven E. H. Hernestam, Kjell B. Martinsson, Erik G. Christensson, Nils-Goran E. Olsson
  • Patent number: 4235875
    Abstract: Novel alkyl 1-(hydroxyalkyl)piperidines and acid addition salts thereof, useful as inhibitors of dental plaque and therefore also useful against dental caries and periodontitis, are disclosed. Methods of making same, orally-acceptable compositions thereof, a method of treating therewith, and important and novel intermediates for the production thereof are also disclosed.
    Type: Grant
    Filed: April 24, 1978
    Date of Patent: November 25, 1980
    Assignee: A.B. Ferrosan
    Inventors: Sven E. H. Hernestam, Lars O. Willard, Aina L. Abramo, Hans-Bertil Johansson
  • Patent number: 4183933
    Abstract: 2,3,4,7,8,9-Substituted octahydropyrazinopyrimidinones and acid addition salts thereof. A process for the preparation of said compounds. A pharmaceutical composition comprising such a compound and a conventional carrier. A process for the preparation of said composition. Method of medical treatment of human beings and animals using such compounds.
    Type: Grant
    Filed: August 30, 1978
    Date of Patent: January 15, 1980
    Assignee: AB Ferrosan
    Inventors: Anders K. K. Bjork, Aina L. Abramo, Sven E. H. Hernestam, Bengt E. S. Kjellberg
  • Patent number: 4144320
    Abstract: Aminoalcohol compounds and acid addition salts thereof, useful in the prevention and treatment of dental caries and periodontitis, are disclosed. Methods of preparing said derivatives, orally acceptable compositions containing said compounds, and a method of treatment therewith are also disclosed.
    Type: Grant
    Filed: April 12, 1977
    Date of Patent: March 13, 1979
    Assignee: AB Ferrosan
    Inventors: Sven E. H. Hernestam, Nils A. Nilsson, Lars-Olof Willard