Patents by Inventor Sven-Erik Hedberg
Sven-Erik Hedberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9162066Abstract: A first ventricle is stimulated at a stimulation site, a point of time for arrival at the AV node for at least one depolarization wave resulting from the stimulation is estimated and a first activation time interval substantially corresponding to the time interval required for at least one depolarization wave to travel from the stimulation site in the first ventricle to the AV node is computed. A similar process is used to compute a second activation time interval for the other ventricle. Based on these activation time intervals and a difference between the intervals, a pacing therapy can be determined.Type: GrantFiled: May 31, 2011Date of Patent: October 20, 2015Assignee: ST. JUDE MEDICAL ABInventors: Sven-Erik Hedberg, Nils Holmstrom, Karin Jarverud
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Patent number: 8918165Abstract: The present invention relates generally to medical devices for electrode positioning during implantation procedures. A cardiac signal measuring device measures cardiac signals sensitive to inherent differences between cardiac tissue and blood using at least one electrode of a medical lead arranged at a distal tip of the medical lead and at least a second electrode arranged at a distance from the distal electrode and being connectable to the measuring unit. An analyzing module acquires cardiac signals measured during predetermined measurement sessions. The analyzing module determines at least one cardiac signal value based on the cardiac signals for each measurement session and analyzes changes of the cardiac signal values between different measurement sessions to determine a position of the electrode relative a tissue border. A maximum of the change of the cardiac signal values between two successive measurement sessions indicates that the electrode has reached the tissue border.Type: GrantFiled: September 28, 2012Date of Patent: December 23, 2014Assignee: St. Jude Medical ABInventors: Sven-Erik Hedberg, Nils Holmstrom, Johan Eckerdal, Torbjorn Persson, Rolf Hill, Fredrik Westman
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Publication number: 20140257423Abstract: The present invention relates generally to implantable medical devices and more particularly to systems and methods for stimulating a heart of a patient. A first ventricle is activated by delivering stimulation to at least one stimulation site, a point of time for arrival at the AV node for at least one depolarization wave resulting from the stimulation in the first ventricle is estimated and a first activation time interval substantially corresponding to the time interval required for at least one depolarization wave to travel from the stimulation site in the first ventricle to the AV node using the estimated point of time for arrival of the depolarization wave and a point of time for delivery of stimulation is computed. Thereafter, the other ventricle is stimulated by delivering stimulation to at least one stimulation site.Type: ApplicationFiled: May 31, 2011Publication date: September 11, 2014Applicant: ST. JUDE MEDICAL ABInventors: Sven-Erik Hedberg, Nils Holmstrom, Karin Jarverud
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Patent number: 8798765Abstract: CRT settings for an implantable medical device are determined by applying pacing pulses to heart chambers of a scheme of different combinations of interchamber delays. A respective width parameter value representing an R or P wave width is determined for each such delay combination based on an ECG representing signal and the width parameter values are employed to estimate a parametric model defining the width parameter as a function of interchamber delays. Candidate interchamber delays that minimize the width parameter are determined from the parametric model and employed to determine optimal CRT settings. The technique provides an efficient way of finding optimal CRT settings when multiple pacing sites are available in a heart chamber.Type: GrantFiled: May 14, 2012Date of Patent: August 5, 2014Assignee: St. Jude Medical ABInventors: Kjell Noren, Anders Bjorling, Tomas Svensson, Sven-Erik Hedberg, Allen Keel, Stuart Rosenberg, Kyungmoo Ryu
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Patent number: 8781580Abstract: An implantable medical device is connected to a multipolar LV lead and an implantable sensor. The sensor signal from the sensor is used to identify a time point of mitral valve closure for a cardiac cycle when a ventricular pulse generator generates pacing pulses that are applied to the electrodes of the multipolar LV lead according to a pacing sequence. A time interval processor determines the time interval from onset of LV activation to the time point of mitral valve closure. This procedure is repeated for multiple different pacing sequences of a sequence set. The pacing sequence that resulted in shortest time interval is then selected by a selector as the currently optimal pacing sequence for the patient.Type: GrantFiled: October 10, 2012Date of Patent: July 15, 2014Assignee: St. Jude Medical ABInventors: Sven-Erik Hedberg, Malin Hollmark, Stefan Hjelm, Michael Broome
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Publication number: 20140094706Abstract: The present invention relates generally to medical devices for electrode positioning during implantation procedures. A cardiac signal measuring device measures cardiac signals sensitive to inherent differences between cardiac tissue and blood using at least one electrode of a medical lead arranged at a distal tip of the medical lead and at least a second electrode arranged at a distance from the distal electrode and being connectable to the measuring unit. An analyzing module acquires cardiac signals measured during predetermined measurement sessions. The analyzing module determines at least one cardiac signal value based on the cardiac signals for each measurement session and analyzes changes of the cardiac signal values between different measurement sessions to determine a position of the electrode relative a tissue border. A maximum of the change of the cardiac signal values between two successive measurement sessions indicates that the electrode has reached the tissue border.Type: ApplicationFiled: September 28, 2012Publication date: April 3, 2014Applicant: ST. JUDE MEDICAL ABInventors: Sven-Erik Hedberg, Nils Holmstrom, Johan Eckerdal, Torbjorn Persson, Rolf Hill, Fredrik Westman
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Patent number: 8630700Abstract: In an implantable heart monitoring device and a monitoring method, an impedance is measured across at least part of an atrium, such that variation of the impedance is related to the volume change of the atrium. Values are stored at different occasions that indicate the rate of change of the measured impedance. The stored values are determined such that, when the device is used in a living being, the variation of the stored values will be related to the variation of the speed with which the atrium is filled with blood during the atrial diastole.Type: GrantFiled: December 19, 2007Date of Patent: January 14, 2014Assignee: St. Jude Medical, ABInventors: Andreas Blomqvist, Nils Holmstöm, Sven-Erik Hedberg, Malin Öhlander
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Patent number: 8626313Abstract: In a piezoelectric sensor, a method for the manufacture thereof, and an implantable lead embodying such a piezoelectric sensor, a layer of piezoelectric material, having aligned, polarized dipoles, is applied to a tubular supporting substrate, the layer of piezoelectric material having at least one electrode at an outer surface thereof and at least one electrode at an inner surface thereof. The piezoelectric material is applied on the inner circumference of the tubular supporting substrate.Type: GrantFiled: April 25, 2006Date of Patent: January 7, 2014Assignee: St. Jude Medical, ABInventors: Tom Eriksson, Kenth Nilsson, Sven-Erik Hedberg
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Patent number: 8620432Abstract: An implantable medical device applies an electric signal over two electrodes and measures the resulting electric signal over a candidate pair of neighboring electrodes on a lead for a first heart ventricle or over a candidate electrode of the lead and a case electrode. An impedance signal is determined for each candidate pair or electrode based on the applied signal and the measured resulting signal. A time difference between start of contraction in a second ventricle and the timing of local myocardial contraction as identified from the impedance signal at the site of the candidate pair or electrode is determined for each candidate pair or electrode. An optimal pacing electrode is selected to correspond to one of the electrodes of the candidate pair having the largest time difference or the candidate electrode having largest time difference.Type: GrantFiled: June 29, 2011Date of Patent: December 31, 2013Assignee: St. Jude Medical ABInventors: Sven-Erik Hedberg, Nils Holmström, John Gustafsson, Andreas Blomqvist, Andreas Karlsson
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Publication number: 20130289642Abstract: An implantable medical device is connected to a multipolar LV lead and an implantable sensor. The sensor signal from the sensor is used to identify a time point of mitral valve closure for a cardiac cycle when a ventricular pulse generator generates pacing pulses that are applied to the electrodes of the multipolar LV lead according to a pacing sequence. A time interval processor determines the time interval from onset of LV activation to the time point of mitral valve closure. This procedure is repeated for multiple different pacing sequences of a sequence set. The pacing sequence that resulted in shortest time interval is then selected by a selector as the currently optimal pacing sequence for the patient.Type: ApplicationFiled: October 10, 2012Publication date: October 31, 2013Inventors: Sven-Erik Hedberg, Malin Hollmark, Stefan Hjelm, Michael Broome
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Patent number: 8565866Abstract: An implantable medical device has an impedance determiner for determining a cardiogenic impedance signal based on electric signals sensed by connected electrodes. A parameter calculator processes the impedance signal to calculate an impedance parameter representative of the cardiogenic impedance in connection with the diastolic phase of a heart cycle. This parameter is then employed by the device for monitoring acute decompensated heart failure status of a subject.Type: GrantFiled: December 21, 2007Date of Patent: October 22, 2013Assignee: St. Jude Medical ABInventors: Andreas Blomqvist, Nils Holmström, Sven-Erik Hedberg, Malin Öhlander
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Patent number: 8532774Abstract: The present invention provides methods for detecting phrenic nerve stimulation. A pacing module is instructed to deliver pacing pulses having a predetermined pulse amplitude and/or width within the refractory period of the left ventricle. The pacing pulses are repeatedly delivered during a number of cardiac cycles and wherein the pacing pulses are delivered at different delays relative to an onset of the refractory period of the left ventricle in different cardiac cycles. Impedance signals are measured in time windows synchronized with the delivery of pacing pulses in the refractory period of the left ventricle using at least one electrode configuration. At least one impedance signal is gathered from each time window, aggregated impedance signals are created using the impedance signals from the different time windows, and the aggregated impedance signals are analyzed to detect PNS.Type: GrantFiled: July 10, 2012Date of Patent: September 10, 2013Assignee: St. Jude Medical ABInventors: Sven-Erik Hedberg, Tomas Svensson, Kjell Noren, Stuart Rosenberg, Kyungmoo Ryu, Edward Karst
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Patent number: 8527051Abstract: The present invention provides implantable medical devices for detecting phrenic nerve stimulation. A pacing module is configured to deliver pacing pulses having a predetermined pulse amplitude and/or width within the refractory period of the left ventricle. The pacing pulses are repeatedly delivered during a number of cardiac cycles, and the pacing pulses are delivered at different delays relative to an onset of the refractory period of the left ventricle in different cardiac cycles. An impedance measurement module is configured to measure impedance signals in time windows synchronized with the delivery of pacing pulses in the refractory period of the left ventricle. A phrenic nerve stimulation, PNS, detection module is configured to gather at least one impedance signal from each time window, create aggregated impedance signals using the impedance signals from the different time windows, and analyze the aggregated impedance signals to detect PNS.Type: GrantFiled: July 10, 2012Date of Patent: September 3, 2013Assignee: St. Jude Medical ABInventors: Sven-Erik Hedberg, Tomas Svensson, Kjell Noren, Stuart Rosenberg, Kyungmoo Ryu, Edward Karst
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Patent number: 8359095Abstract: In a medical system and a method for operating such a system, the system includes an implantable medical device of a patient, a programmer device, and an extracorporeal stress equipment adapted to exert a physiological stress on the patient, for automatically determining settings of a sensor for sensing a physiological parameter of the patient or for automatically determining a pacing setting of the device over a broad range of workloads of the equipment. The ingoing units and/or devices of the medical system, i.e. the implantable medical device of the patient, the programmer device, and the extracorporeal stress equipment, communicate bi-directionally with each other and form a closed loop.Type: GrantFiled: September 25, 2006Date of Patent: January 22, 2013Assignee: Pacesetter, Inc.Inventors: Sven-Erik Hedberg, Patrik Malmberg, Leif Lychou, Jürgen Kerstna
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Patent number: 8355782Abstract: Implantable heart stimulator connectable to an electrode arrangement has a pulse generator adapted to deliver stimulation pulses to a heart of a subject; an impedance measurement unit adapted monitor at least one heart chamber of the heart of the subject to measure the impedance in the at least one monitored heart chamber for generating an impedance signal corresponding to the measured impedance. The impedance signal is applied to a processor where the signal is processed, according to specified criteria, and a fractionation index value is determined represented by the curve length of the impedance signal during a predetermined measurement period. The fractionation index value is a measure of different degrees of mechanical dyssynchrony of the heart.Type: GrantFiled: January 28, 2008Date of Patent: January 15, 2013Assignee: St. Jude Medical ABInventors: Andreas Blomqvist, Nils Holmström, Malin Öhlander, Sven-Erik Hedberg
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Patent number: 8346353Abstract: An implantable medical system for detecting incipient edema has an implantable medical lead including an optical sensor having a light source and a light detector. The medical system further has an edema detection circuit that activates the light source to emit light, the light being directed into lung tissue of a patient and that obtains a light intensity value corresponding to an intensity of light received by the light detector, and that evaluates the light intensity value to detect a consistency with incipient edema.Type: GrantFiled: April 24, 2007Date of Patent: January 1, 2013Assignee: St. Jude Medical ABInventors: Sven-Erik Hedberg, Andreas Blomqvist, Karin Järverud, Karin Ljungström, Leif Lindqvist, Urban Lönn
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Publication number: 20120310296Abstract: CRT settings for an implantable medical device are determined by applying pacing pulses to heart chambers of a scheme of different combinations of interchamber delays. A respective width parameter value representing an R or P wave width is determined for each such delay combination based on an ECG representing signal and the width parameter values are employed to estimate a parametric model defining the width parameter as a function of interchamber delays. Candidate interchamber delays that minimize the width parameter are determined from the parametric model and employed to determine optimal CRT settings. The technique provides an efficient way of finding optimal CRT settings when multiple pacing sites are available in a heart chamber.Type: ApplicationFiled: May 14, 2012Publication date: December 6, 2012Applicant: ST. JUDE MEDICAL ABInventors: Kjell Noren, Anders Bjorling, Tomas Svensson, Sven-Erik Hedberg, Allen Keel, Stuart Rosenberg, Kyungmoo Ryu
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Patent number: 8321016Abstract: In a method and implantable medical device for ventricular tachyarrhythmia detection and classification, upon detection of a ventricular tachyarrhythmia based on an electrocardiogram signal, cardiogenic impedance data representative of ventricular volume dynamics are collected and used for classifying the detected tachyarrhythmia as stable or unstable. In the latter case but typically not in the former case, defibrillation shocks or other forms of therapy are applied to combat the unstable ventricular tachyarrhythmia.Type: GrantFiled: June 13, 2007Date of Patent: November 27, 2012Assignee: St. Jude Medical ABInventors: Nils Holmström, Andreas Blomqvist, Sven-Erik Hedberg, Malin Öhlander
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Patent number: 8219194Abstract: In a system and method for monitoring cardiac synchrony in a human heart, a first sensor is positioned at a first cardiac wall location that is subject to movements related to longitudinal valve plane movements along the longitudinal axis of the heart, and measures the cardiac wall movements at the first cardiac wall location and a second sensor is positioned at a second cardiac wall location that is subject to movements related to longitudinal valve plane movements along the longitudinal axis of the heart, and measures the cardiac wall movements at the second cardiac wall location. A lead arrangement conducts respective output signals from the first and second sensors to processing circuitry that processes the first and second sensor output signals to produce a synchronization signal therefrom indicative of synchrony in the respective valve plane movements at the first and second cardiac wall locations.Type: GrantFiled: October 12, 2011Date of Patent: July 10, 2012Assignee: St. Jude Medical ABInventors: Karin Järverud, Kenth Nilsson, Sven-Erik Hedberg
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Publication number: 20120089035Abstract: In a system and method for monitoring cardiac synchrony in a human heart, a first sensor is positioned at a first cardiac wall location that is subject to movements related to longitudinal valve plane movements along the longitudinal axis of the heart, and measures the cardiac wall movements at the first cardiac wall location and a second sensor is positioned at a second cardiac wall location that is subject to movements related to longitudinal valve plane movements along the longitudinal axis of the heart, and measures the cardiac wall movements at the second cardiac wall location. A lead arrangement conducts respective output signals from the first and second sensors to processing circuitry that processes the first and second sensor output signals to produce a synchronization signal therefrom indicative of synchrony in the respective valve plane movements at the first and second cardiac wall locations.Type: ApplicationFiled: October 12, 2011Publication date: April 12, 2012Inventors: KARIN JÄRVERUD, Kenth Nilsson, Sven-Erik Hedberg