Patents by Inventor Sven Grabowski
Sven Grabowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6498232Abstract: Shear forces are used for essentially salt-free coagulation of plastics dispersions or rubber dispersions. For this, method of use is made of an apparatus with at least one shearing module which has a stator and a rotor arranged within the stator, where the surfaces facing toward one another in the stator and in the rotor are in each case smooth, or at least the rotor exhibits a structure formed on its surface and facing from this in the direction of the stator, and between the stator and the rotor there is a gap of predetermined gap width. The process is carried out by passing the dispersion to be coagulated through the gap between stator and rotor and precipitating the dispersion by rotation of the rotor with predetermined shear rate and shear deformation.Type: GrantFiled: May 31, 2001Date of Patent: December 24, 2002Assignee: BASF AktiengesellschaftInventors: Norbert Güntherberg, Jürgen Hofmann, Alexander Ludwig, Hartmut Heinen, Gerd Ehrmann, Peter Barghoorn, Andreas Kleinke, Sven Grabowski, Rainer Nachtrab, Bernhard Czauderna
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Patent number: 6323279Abstract: A thermoplastic molding composition having little intrinsic color is produced from a graft copolymer and a thermoplastic polymer. The graft copolymer is produced from a soft elastomeric particulate graft base obtained by polymerization of a conjugated diene alone or with a small amount of a monoethylenically unsaturated monomer, upon which is grafted a vinylaromatic monomer and acrylonitrile and optionally another monoethylenically unsaturated monomer. The thermoplastic polymer is a copolymer of a vinylaromatic monomer and acrylonitrile and optionally an additional monoethylenically unsaturated monomer. The thermoplastic molding composition has a low level of intrinsic color coupled with good mechanical properties and can be processed by, for example, extrusion, injection molding, calendaring, blow molding, compression molding, or sintering.Type: GrantFiled: December 30, 1999Date of Patent: November 27, 2001Assignee: BASF AktiengesellschaftInventors: Norbert Güntherberg, Jürgen Koch, Peter Ittemann, Joachim Seibring, Sven Grabowski, Graham Edmund McKee, Norbert Mosbach, Bernhard Czauderna, Norbert Niessner, Hartmut Heinen
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Patent number: 6290990Abstract: Slow-release matrix pellets with a spherical or lenticular shape and uniform maximum diameters in the range from 0.5 to 4 mm, composed of a) 0.1-87% by weight of at least one biologically active compound, b) 5-50% by weight of at least one water-insoluble polymer, c) 5-45% by weight of at least one lipophilic component as plasticizer for polymer b), d) 3-40% by weight of a natural or semisynthetic gel former, e) 0-50% by weight of one or more conventional formulation aids.Type: GrantFiled: October 17, 1996Date of Patent: September 18, 2001Assignee: BASF AktiengesellschaftInventors: Sven Grabowski, Joerg Rosenberg, Axel Sanner
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Patent number: 6165399Abstract: A process for preparing thermoplastics or polymer blends comprising (A) from 5 to 95% of a water-moist elastomer component containing up to 60% of residual water, (B) from 5 to 95% of a thermoplastic polymer, (C) from 0 to 95% of a further polymer, and (D) from 0 to 70% of additives, said process comprising mixing the components A to D in an extruder with mechanical dewatering of component A, wherein the extruder has at least two rotating screws and, in the conveying direction, is essentially composed of a metering section into which component A is fed, a squeeze section which serves for dewatering component A and contains a retarding element and an associated dewatering orifice which is present upstream of the retarding element by a distance corresponding to at least one screw diameter, a feed section in which the thermoplastic polymer B is introduced as a melt into the extruder, a plastication section with mixing or kneading elements, a devolatilization section with an orifice and in which the remaining watType: GrantFiled: March 25, 1999Date of Patent: December 26, 2000Assignee: BASF AktiengesellschaftInventors: Norbert Guntherberg, Jurgen Hofmann, Elmar Mailahn, Hilmar Ohlig, Bernhard Czauderna, Sven Grabowski, Klaus Bus
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Patent number: 6111012Abstract: Graft copolymers (P1) contain, in any desired sequence, at least (P1.1) a hard segment having a glass transition temperature of at least 11.degree. C., which contains at least one vinylaromatic monomer as the monomer or as one of two or more monomers copolymerizable with one another and a crosslinker component comprising at least dihydrodicyclopentadienyl acrylate as a crosslinking agent having two or more functional groups of different reactivity and at least one crosslinking agent having two or more functional groups of the same reactivity, and (P1.2) a soft segment having a glass transition temperature of not more than 10.degree. C., which contains at least one acrylate as the monomer or as one of two or more monomers copolymerizable with one another, and blends and thermoplastic materials contain said graft copolymers.Type: GrantFiled: December 22, 1997Date of Patent: August 29, 2000Assignee: BASF AktiengesellschaftInventors: Michael Fischer, Jurgen Koch, Bernhard Rosenau, Graham Edmund Mc Kee, Sven Grabowski, Norbert Mosbach, Wolfgang Fischer, Walter Heckmann
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Patent number: 5958316Abstract: Toughened thermoplastics are prepared by mechanically dewatering a water-moist elastomer component A containing up to 50% by weight of residual water and mixing the resulting dewatered elastomer component A' with a thermoplastic polymer B in a mixing unit, by a process in which the elastomer component A is fed to a twin-screw extruder which has corotating screws and essentially includes, in the transport direction,one unheated metering section in which the elastomer component A is fed to the extruder by a metering means,at least one unheated squeeze section which serves for dewatering and contains at least one retarding element and in each case at least one associated dewatering orifice,at least one section in which the thermoplastic polymer B is introduced as a melt into the extruder,at least one section provided with mixing, kneading or other plasticating elements or combinations of these elements,at least one devolatilization section which is provided with at least one devolatilization orifice and in whichType: GrantFiled: March 22, 1996Date of Patent: September 28, 1999Assignee: BASF AktiengesellschaftInventors: Norbert Guntherberg, Jurgen Hofmann, Hilmar Ohlig, Elmar Mailahn, Klaus Bus, Bernhard Czauderna, Sven Grabowski
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Patent number: 5939099Abstract: Solid preparations are obtainable by melt extrusion ofA) at least one active compound,B) a mixture ofB1) from 10 to 90% by weight of a water-soluble, thermoplastic polymer, andB2) from 10 to 90% by weight of a low-substituted hydroxypropylcellulose, andC) from 0 to 50% by weight, based on the total amount of the preparation, of customary pharmaceutical auxiliaries.Type: GrantFiled: July 30, 1997Date of Patent: August 17, 1999Assignee: BASF AktiengesellschaftInventors: Sven Grabowski, Jorg Breitenbach, Joerg Rosenberg, Axel Sanner
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Patent number: 5910276Abstract: Toughened thermoplastics are prepared by mechanically dewatering a water-moist elastomer component A containing up to 60% by weight of residual water and mixing the resulting dewatered elastomer component A' with a thermoplastic polymer B in an extruder, by a process in which the elastomer component A is fed to a twin-screw extruder which has corotating, in each case double-flight, screws and essentially includes, in the transport direction,a metering section in which the elastomer component A is fed to the extruder by a metering means,at least one squeeze section which serves for dewatering and contains at least one retarding element and in each case at least one associated dewatering orifice,at least one section provided with a conveying screw or at least one section provided with mixing, kneading or other plasticating elements or combinations of these elements,at least one section in which the thermoplastic polymer B is introduced as a melt into the extruder,at least one section provided with mixing, kneadType: GrantFiled: March 22, 1996Date of Patent: June 8, 1999Assignee: BASF AktiengesellschaftInventors: Norbert Guntherberg, Jurgen Hofmann, Hilmar Ohlig, Elmar Mailahn, Klaus Bus, Bernhard Czauderna, Sven Grabowski
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Patent number: 5897910Abstract: The present invention is a process for the production of covered tablets by melt calendering in which the melt containing active ingredient is introduced between two sheets of the covering material into the molding rolls.Type: GrantFiled: June 20, 1997Date of Patent: April 27, 1999Assignee: BASF AktiengesellschaftInventors: Joerg Rosenberg, Werner Maier, Sven Grabowski, Jorg Breitenbach
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Patent number: 5852113Abstract: Toughened thermoplastics are prepared by mixing a water-moist elastomer component A containing up to 60% by weight of residual water with a thermoplastic polymer B and further polymers C and additives D in an extruder with mechanical dewatering of the elastomer component A, by a process in which the components A, B, C and D are fed to a twin-screw extruder which has corotating screws and essentially comprises, in the transport direction,at least one metering section in which the elastomer component A is fed to the extruder by a metering means,at least one squeeze section which serves for dewatering the component A and contains at least one retarding element and in each case at least one associated dewatering orifice,at least one section in which the thermoplastic polymer B is introduced as a melt into the extruder,at least one section provided with mixing, kneading or other plasticating elements or combinations of these elements,at least one devolatilization section which is provided with at least one devolatType: GrantFiled: March 22, 1996Date of Patent: December 22, 1998Assignee: BASF AktiengesellschaftInventors: Norbert Guntherberg, Jurgen Hofmann, Elmar Mailahn, Hilmar Ohlig, Sven Grabowski, Bernhard Czauderna, Klaus Bus
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Patent number: 5753770Abstract: A fluidized-bed process for preparing hydrogen peroxide, C.sub.1 -C.sub.4 -monopercarboxylic acids and C.sub.4 -C.sub.18 -dipercarboxylic acid complexes in which a solution of hydrogen peroxide, a C.sub.1 -C.sub.4 -monopercarboxylic acid, a C.sub.4 -C.sub.18 -dipercarboxylic acid or a mixture thereof in water or carboxylic acids is applied to a pulverulent or pregranulated matrix and fluidized-bed drying takes place.Type: GrantFiled: June 21, 1996Date of Patent: May 19, 1998Assignee: BASF AktiengesellschaftInventors: Jorg Breitenbach, Sven Grabowski, Axel Sanner
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Patent number: 5684040Abstract: Compositions in the form of solid solutions containinga) 1-90% by weight of a coumarin derivative A from the group of alkoxycoumarins with a heterocyclic substituent or of hydroxycoumarins esterified with a sulfonic acid as active substance andb) 10-99% by weight of at least one water-soluble polymer B as carrier substance.Type: GrantFiled: November 7, 1995Date of Patent: November 4, 1997Assignee: BASF AktiengesellschaftInventors: Sven Grabowski, Winfried Mueller, Joerg Rosenberg, Rudolf Binder, Axel Sanner
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Patent number: 5641516Abstract: Compositions which contain active substances and are in the form of solid particles can be obtained by intimately mixing the active substance with a water-soluble melt composed ofa) 10-90% by weight of a water-soluble polymer A with a viscosity V.sub.a of 1,000-120,000 cps andb) 10-90% by weight of a water-soluble polymer B with a viscosity V.sub.b of 1-500 cpsas carrier substance, where the viscosities V.sub.a and V.sub.b are those of a 2% by weight aqueous solution at 20.degree. C., measured by the ASTM D 2363-72 capillary method (European Pharmacopoeia, Vol. III, p. 37), and processing the melt with shaping to give the particles.Type: GrantFiled: August 7, 1995Date of Patent: June 24, 1997Assignee: BASF AktiengesellschaftInventors: Sven Grabowski, Axel Sanner, Joerg Rosenberg
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Patent number: 5552159Abstract: A solid depot drug form produced by melt extrusion at from 50.degree. to 200.degree. C. and continuous shaping of a mixture of from 0.1 to 70% by weight, based on the finished depot form, of a pharmaceutical active ingredient with a polymer melt of the following composition:a) at least 6% by weight, based on the complete depot form, of at least one water-insoluble poly(meth) acrylate with a glass transition temperature Tg in the range from -60.degree. to 180.degree. C.,b) a water-soluble hydroxyalkylcellulose or hydroxy-alkylmethylcellulose with 2 or 3 carbons in the hydroxyalkyl, or an N-vinylpyrrolidone polymer with from 0 to 50% by weight of vinyl acetate or a mixture of the two in the ratio a):b) =5:95 to 95:5, andc) 0-30% by weight, based on the finished depot form, of one or more conventional pharmaceutical auxiliaries.Type: GrantFiled: September 23, 1993Date of Patent: September 3, 1996Assignee: BASF AktiengesellschaftInventors: Winfried Mueller, Reinhard Spengler, Sven Grabowski, Axel Sanner
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Patent number: 5490990Abstract: A process for the production of solid pharmaceutical depot forms by application of a reconstituted aqueous dispersion of a pharmaceutically acceptable binder to a core which contains active substance or by wet granulation of the pharmaceutical active substance with such a binder dispersion or by direct tableting of an active substance with the redispersible binder powder, wherein the binder has been obtained by emulsion polymerization and subsequent spray drying of the resulting aqueous dispersion with a water-soluble pharmaceutically acceptable spraying aid with a glass transition temperature of at least 60.degree. C. and with or without a pharmaceutically acceptable antiblocking agent.Type: GrantFiled: June 21, 1993Date of Patent: February 13, 1996Assignee: BASF AktiengesellschaftInventors: Sven Grabowski, Astrid Kah-Helbig, Axel Sanner, Kurt Wendel
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Patent number: 5426163Abstract: A process for preparing a free-flowing redispersible powder composed of a vinyl-pyrrolidone/vinyl acetate copolymer containing 15-40% by weight of vinylpyrrolidone units wherein the mixture of the monomers is copolymerized in organic solution, the resulting solution is, after addition of a surfactant, subjected to replacement of the solvent by water, and the resulting dispersion is spray- or freeze-dried, and the use of the redispersible powder for producing paints and coating compositions, glues and adhesives and, in particular, the matrix and/or coating of solid slow-release pharma-ceutical forms and of hair-spray formulations are described.Type: GrantFiled: September 19, 1994Date of Patent: June 20, 1995Assignee: BASF AktiengesellschaftInventors: Volker Buehler, Sven Grabowski, Axel Sanner
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Patent number: 5326586Abstract: A process for coating drug forms by application of an aqueous dispersion which contains as binder a redispersed latex of an emulsion polymer onto the drug form and evaporating the water at a temperature at which the latex particles form a film, comprises employing a polymer dispersion which has been prepared by emulsion polymerization of one part by weight of at least one ethylenically unsaturated polymerizable monomer, by means of initiators which provide free radicals, in the presence of from 0.1 to 2 parts by weight of saccharified starch, and from 0 to 5% by weight, based on the monomer or monomers, of a surfactant, with or without further conventional additives, drying to a powder and redispersing in water.Type: GrantFiled: October 7, 1992Date of Patent: July 5, 1994Assignee: BASF AktiengesellschaftInventors: Sven Grabowski, Kurt Wendel, Astrid Kah-Helbig