Patents by Inventor Sven Jacobsson

Sven Jacobsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240080073
    Abstract: According to certain embodiments, a method (1100) by a wireless (110) is provided for receiving (1102), from a network node (160), an indication of a particular one of a plurality of sounding reference signal, SRS, configurations for an antenna switching configuration, ASC. At least one SRS is transmitted (1104) to the network node based on the particular one of the plurality of SRS configurations for the ASC.
    Type: Application
    Filed: December 22, 2021
    Publication date: March 7, 2024
    Inventors: Mattias Frenne, Sven Jacobsson, Eleftherios Karipidis, Andreas Nilsson
  • Publication number: 20240080160
    Abstract: According to some embodiments, a method performed by a wireless device comprises receiving a sounding reference signal (SRS) configuration for a SRS resource set. The SRS resource set comprises a plurality of SRS resources. The SRS configuration comprises a first periodicity for a first subset of the plurality of SRS resources and a second periodicity for a second subset of the plurality of SRS resources. The method further comprises transmitting the first subset of SRS resources according to the first periodicity and transmitting the second subset of SRS resources according to the second periodicity.
    Type: Application
    Filed: January 18, 2022
    Publication date: March 7, 2024
    Inventors: Robert Mark Harrison, Andreas Nilsson, Sven Jacobsson
  • Publication number: 20240080086
    Abstract: According to some embodiments, a wireless device comprises up to eight transmit and receive chains. A method performed by the wireless device comprises: obtaining a sounding reference signal (SRS) antenna switching capability of the wireless device, the antenna switching capability including one or more antenna switching configurations (ASCs); transmitting the SRS antenna switching capability to a network node; and receiving, from the network node, a SRS configuration for one or more SRS resource sets based on at least one of the ASCs.
    Type: Application
    Filed: January 18, 2022
    Publication date: March 7, 2024
    Inventors: Andreas Nilsson, Mattias Frenne, Sven Jacobsson
  • Publication number: 20240080145
    Abstract: According to some embodiments, a method is performed by a wireless device comprises: receiving a sounding reference signal (SRS) configuration comprising a frequency hopping pattern over a plurality of slots wherein a frequency domain starting position varies per slot; and transmitting SRS according to the received SRS configuration.
    Type: Application
    Filed: January 18, 2022
    Publication date: March 7, 2024
    Inventors: Andreas Nilsson, Eleftherios Karipidis, Robert Mark Harrison, Sven Jacobsson, Sven Petersson
  • Publication number: 20240080161
    Abstract: According to certain embodiments, a method performed by a wireless device comprises receiving sounding reference signal (SRS) configuration information from a network node. The SRS configuration information indicates a configuration associated with one or more SRS resources. At least a portion of the SRS configuration information is received in one or more Medium Access Control-Control Element (MAC-CE) messages. The method further comprises configuring the one or more SRS resources based at least in part on the SRS configuration information.
    Type: Application
    Filed: January 18, 2022
    Publication date: March 7, 2024
    Inventors: Andreas Nilsson, Helka-Liina Määttänen, Mattias Frenne, Sven Jacobsson
  • Publication number: 20240072965
    Abstract: There is provided a method in a wireless device for uplink transmissions associated with a plurality of reference signal (RS) resources that belong to a plurality of resource sets. The method comprises: receiving downlink control information (DCI) indicating an uplink transmission, the DCI further comprising an indication of one or more RS resources from the plurality of RS resources, the one or more RS resources belonging to the plurality of resource sets; and performing the uplink transmission based on the indication of the one or RS resources in the DCI.
    Type: Application
    Filed: January 18, 2022
    Publication date: February 29, 2024
    Inventors: Mattias FRENNE, Sven JACOBSSON, Eleftherios KARIPIDIS, Andreas NILSSON
  • Publication number: 20230396387
    Abstract: According to certain embodiments, a method performed by a wireless device comprises determining a configuration for sounding reference signal (SRS) transmission. The configuration is determined at least in part based on information received from a network node. The method further comprises performing the SRS transmission according to the configuration.
    Type: Application
    Filed: October 22, 2021
    Publication date: December 7, 2023
    Inventors: Robert Mark Harrison, Mattias Frenne, Andreas Nilsson, Xinlin Zhang, Fredrik Athley, Sven Jacobsson, Eleftherios Karipidis
  • Publication number: 20230224124
    Abstract: Systems and methods are disclosed herein that relate to an enhanced guard period between Sounding Reference Signal (SRS) resources. In one embodiment, a method performed by a wireless communication device comprises receiving a SRS configuration from a radio access node, wherein the SRS configuration defines SRS resources in compliance with a predefined or preconfigured minimum guard period between adjacent SRS resources in different slots. The method further comprises transmitting SRSs in accordance with the SRS configuration. In this manner, improved SRS guard period specification is provided, which leads to a better trade-off between SRS signal quality and SRS resource utilization.
    Type: Application
    Filed: August 31, 2021
    Publication date: July 13, 2023
    Inventors: Andreas Nilsson, Sven Jacobsson, Robert Mark Harrison, Eleftherios Karipidis
  • Publication number: 20230224059
    Abstract: Methods and apparatus in a fifth-generation wireless communications, including an example method, in a wireless device, that includes receiving a downlink signal comprising an uplink access configuration index, using the uplink access configuration index to identify an uplink access configuration from among a predetermined plurality of uplink access configurations, and transmitting to the wireless communications network according to the identified uplink access configuration. The example method further includes, in the same wireless device, receiving, in a first subframe, a first Orthogonal Frequency-Division Multiplexing (OFDM) transmission formatted according to a first numerology and receiving, in a second subframe, a second OFDM transmission formatted according to a second numerology, the second numerology differing from the first numerology. Variants of this method, corresponding apparatuses, and corresponding network-side methods and apparatuses are also disclosed.
    Type: Application
    Filed: January 5, 2023
    Publication date: July 13, 2023
    Inventors: Stefan Parkvall, Janne Peisa, Gunnar Mildh, Robert Baldemair, Stefan Wager, Jonas Kronander, Karl Werner, Richard Abrahamsson, Ismet Aktas, Peter Alriksson, Junaid Ansari, Shehzad Ali Ashraf, Henrik Asplund, Fredrik Athley, Håkan Axelsson, Joakim Axmon, Johan Axnäs, Kumar Balachandran, Gunnar Bark, Jan-Erik Berg, Andreas Bergström, Håkan Björkegren, Nadia Brahmi, Cagatay Capar, Anders Carlsson, Andreas Cedergren, Mikael Coldrey, Icaro L. J. da Silva, Erik Dahlman, Ali El Essaili, Ulrika Engström, Mårten Ericson, Erik Eriksson, Mikael Fallgren, Rui Fan, Gabor Fodor, Pål Frenger, Jonas Fridén, Jonas Fröberg Olsson, Anders Furuskär, Johan Furuskog, Virgile Garcia, Ather Gattami, Fredrik Gunnarsson, Ulf Gustavsson, Bo Hagerman, Fredrik Harrysson, Ning He, Martin Hessler, Kimmo Hiltunen, Songnam Hong, Dennis Hui, Jörg Huschke, Tim Irnich, Sven Jacobsson, Niklas Jaldén, Simon Järmyr, Zhiyuan Jiang, Martin Johansson, Niklas Johansson, Du Ho Kang, Eleftherios Karipidis, Patrik Karlsson, Ali S. Khayrallah, Caner Kilinc, Göran N. Klang, Sara Landström, Christina Larsson, Gen Li, Lars Lindbom, Robert Lindgren, Bengt Lindoff, Fredrik Lindqvist, Jinhua Liu, Thorsten Lohmar, Qianxi Lu, Lars Manholm, Ivana Maric, Jonas Medbo, Qingyu Miao, Reza Moosavi, Walter Müller, Elena Myhre, Karl Norrman, Bengt-Erik Olsson, Torgny Palenius, Sven Petersson, Jose Luis Pradas, Mikael Prytz, Olav Queseth, Pradeepa Ramachandra, Edgar Ramos, Andres Reial, Thomas Rimhagen, Emil Ringh, Patrik Rugeland, Johan Rune, Joachim Sachs, Henrik Sahlin, Vidit Saxena, Nima Seifi, Yngve Selén, Eliane Semaan, Sachin Sharma, Cong Shi, Johan Sköld, Magnus Stattin, Anders Stjernman, Dennis Sundman, Lars Sundström, Miurel Isabel Tercero Vargas, Claes Tidestav, Sibel Tombaz, Johan Torsner, Hugo Tullberg, Jari Vikberg, Peter von Wrycza, Thomas Walldeen, Pontus Wallentin, Hai Wang, Ke Wang Helmersson, Jianfeng Wang, Yi-Pin Eric Wang, Niclas Wiberg, Emma Wittenmark, Osman Nuri Can Yilmaz, Ali Zaidi, Zhan Zhang, Zhang Zhang, Yanli Zheng
  • Publication number: 20230179347
    Abstract: A method, system and apparatus are disclosed. According to one or more embodiments, a network node configured to communicate with a wireless device is provided. The network node includes processing circuitry configured to: trigger a first aperiodic, AP, reference signal transmission using a reference signal trigger state; and trigger a second AP reference signal transmission using the reference signal trigger state associated with the first AP reference signal transmission, the second AP reference signal transmission is configured to use at least one different frequency resource than the first AP reference signal transmission.
    Type: Application
    Filed: May 14, 2021
    Publication date: June 8, 2023
    Inventors: Andreas NILSSON, Mattias FRENNE, Sven JACOBSSON
  • Publication number: 20230179368
    Abstract: A method, system and apparatus are disclosed. According to one or more embodiments, a network node configured to communicate with a wireless device is provided. The network node includes processing circuitry configured to receive an indication of a wireless device capability to maintain phase coherence within a predefined tolerance for reference signals transmitted by the wireless device in different time slots, receive a first reference signal transmission in a first time slot and a second reference signal transmission in a second time slot where the first reference signal transmission is an aperiodic, AP, reference signal transmission, and perform channel estimation at least in part by combining the first reference signal transmission and the second reference signal transmission.
    Type: Application
    Filed: May 14, 2021
    Publication date: June 8, 2023
    Inventors: Andreas NILSSON, Mattias FRENNE, Sven JACOBSSON, Sven PETERSSON
  • Patent number: 11652562
    Abstract: Methods and apparatus in a fifth-generation wireless communications, including an example method, in a wireless device, that includes receiving a downlink signal comprising an uplink access configuration index, using the uplink access configuration index to identify an uplink access configuration from among a predetermined plurality of uplink access configurations, and transmitting to the wireless communications network according to the identified uplink access configuration. The example method further includes, in the same wireless device, receiving, in a first subframe, a first Orthogonal Frequency-Division Multiplexing (OFDM) transmission formatted according to a first numerology and receiving, in a second subframe, a second OFDM transmission formatted according to a second numerology, the second numerology differing from the first numerology. Variants of this method, corresponding apparatuses, and corresponding network-side methods and apparatuses are also disclosed.
    Type: Grant
    Filed: December 31, 2020
    Date of Patent: May 16, 2023
    Assignee: Telefonaktiebolaget LM Ericsson (publ)
    Inventors: Stefan Parkvall, Janne Peisa, Gunnar Mildh, Robert Baldemair, Stefan Wager, Jonas Kronander, Karl Werner, Richard Abrahamsson, Ismet Aktas, Peter Alriksson, Junaid Ansari, Shehzad Ali Ashraf, Henrik Asplund, Fredrik Athley, Håkan Axelsson, Joakim Axmon, Johan Axnäs, Kumar Balachandran, Gunnar Bark, Jan-Erik Berg, Andreas Bergström, Häkan Björkegren, Nadia Brahmi, Cagatay Capar, Anders Carlsson, Andreas Cedergren, Mikael Coldrey, Icaro L. J. da Silva, Erik Dahlman, Ali el Essaili, Ulrika Engström, Mårten Ericson, Erik Eriksson, Mikael Fallgren, Rui Fan, Gabor Fodor, Pål Frenger, Jonas Fridén, Jonas Fröberg Olsson, Anders Furuskär, Johan Furuskog, Virgile Garcia, Ather Gattami, Fredrik Gunnarsson, Ulf Gustavsson, Bo Hagerman, Fredrik Harrysson, Ning He, Martin Hessler, Kimmo Hiltunen, Songnam Hong, Dennis Hui, Jörg Huschke, Tim Irnich, Sven Jacobsson, Niklas Jaldén, Simon Järmyr, Zhiyuan Jiang, Niklas Johansson, Martin Johansson, Du Ho Kang, Eleftherios Karipidis, Patrik Karlsson, Ali S. Khayrallah, Caner Kilinc, Göran N. Klang, Sara Landström, Christina Larsson, Gen Li, Lars Lindbom, Robert Lindgren, Bengt Lindoff, Fredrik Lindqvist, Jinhua Liu, Thorsten Lohmar, Qianxi Lu, Lars Manholm, Ivana Maric, Jonas Medbo, Qingyu Miao, Reza Moosavi, Walter Muller, Elena Myhre, Karl Norrman, Bengt-Erik Olsson, Torgny Palenius, Sven Petersson, Jose Luis Pradas, Mikael Prytz, Olav Queseth, Pradeepa Ramachandra, Edgar Ramos, Andres Reial, Thomas Rimhagen, Emil Ringh, Patrik Rugeland, Johan Rune, Joachim Sachs, Henrik Sahlin, Vidit Saxena, Nima Seifi, Yngve Selén, Eliane Semaan, Sachin Sharma, Cong Shi, Johan Sköld, Magnus Stattin, Anders Stjernman, Dennis Sundman, Lars Sundström, Miurel Isabel Tercero Vargas, Claes Tidestav, Sibel Tombaz, Johan Torsner, Hugo Tullberg, Jari Vikberg, Peter von Wrycza, Thomas Walldeen, Pontus Wallentin, Hai Wang, Ke Wang Helmersson, Jianfeng Wang, Yi-Pin Eric Wang, Niclas Wiberg, Emma Wittenmark, Osman Nuri Can Yilmaz, Ali Zaidi, Zhan Zhang, Zhang Zhang, Yanli Zheng
  • Patent number: 11632151
    Abstract: Disclosed is a method of a first wireless communication device configured for massive multi-user multiple-input multiple output (MU-MEMO) communication with two or more second wireless communication devices. The first wireless communication device comprises a plurality of antenna ports, each antenna port associated with at least one of a digital-to-analog converter (DAC) and an analog-to-digital converter (ADC). The method comprises acquiring an estimation of a communication channel between the first wireless communication device and the second wireless communication devices and acquiring an estimation of a quantization distortion caused by either DACs or ADCs. The method also comprises jointly determining (for the two or more second wireless communication devices) a transmission power and a transmission resource for each of the second wireless communication devices, wherein the joint determination is based on the estimation of the communication channel and on the estimation of the quantization distortion.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: April 18, 2023
    Assignee: TELEFONAKTIEBOLAGET LM ERICSSON (PUBL)
    Inventors: Sven Jacobsson, Mikael Coldrey, Andreas Nilsson, Giuseppe Durisi
  • Publication number: 20230109947
    Abstract: Methods and apparatus in a fifth-generation wireless communications network, including an example method, in a wireless device, that includes determining a reporting quality threshold for a parameter related to channel state information (CSI); performing a measurement for each of a plurality of beams from a first predetermined set of beams for evaluation; evaluating the measurement for each of the plurality of beams against the reporting quality threshold; discontinuing the performing and evaluating of measurements in response to determining that the reporting quality threshold is met for one of the beams, such that one or more beams in the first predetermined set of beams are not measured and evaluated; and reporting, to the wireless communications network, CSI for the one of the beams.
    Type: Application
    Filed: June 8, 2022
    Publication date: April 13, 2023
    Inventors: Stefan Parkvall, Janne Peisa, Gunnar Mildh, Robert Baldemair, Stefan Wager, Jonas Kronander, Karl Werner, Richard Abrahamsson, Ismet Aktas, Peter Alriksson, Junaid Ansari, Shehzad Ali Ashraf, Henrik Asplund, Fredrik Athley, Håkan Axelsson, Joakim Axmon, Johan Axnäs, Kumar Balachandran, Gunnar Bark, Jan-Erik Berg, Andreas Bergström, Håkan Björkegren, Nadia Brahmi, Cagatay Capar, Anders Carlsson, Andreas Cedergren, Mikael Coldrey, Icaro L. J. da Silva, Erik Dahlman, Ali El Essaili, Ulrika Engström, Mårten Ericson, Erik Eriksson, Mikael Fallgren, Rui Fan, Gabor Fodor, Pål Frenger, Jonas Fridén, Jonas Fröberg Olsson, Anders Furuskär, Johan Furuskog, Virgile Garcia, Ather Gattami, Fredrik Gunnarsson, Ulf Gustavsson, Bo Hagerman, Fredrik Harrysson, Ning He, Martin Hessler, Kimmo Hiltunen, Songnam Hong, Dennis Hui, Jörg Huschke, Tim Irnich, Sven Jacobsson, Niklas Jaldén, Simon Järmyr, Zhiyuan Jiang, Martin Johansson, Niklas Johansson, Du Ho Kang, Eleftherios Karipidis, Patrik Karlsson, Ali S. Khayrallah, Caner Kilinc, Göran N. Klang, Sara Landström, Christina Larsson, Gen Li, Bo Lincoln, Lars Lindbom, Robert Lindgren, Bengt Lindoff, Fredrik Lindqvist, Jinhua Liu, Thorsten Lohmar, Qianxi Lu, Lars Manholm, Ivana Maric, Jonas Medbo, Qingyu Miao, Reza Moosavi, Walter Müller, Elena Myhre, Johan Nilsson, Karl Norrman, Bengt-Erik Olsson, Torgny Palenius, Sven Petersson, Jose Luis Pradas, Mikael Prytz, Olav Queseth, Pradeepa Ramachandra, Edgar Ramos, Andres Reial, Thomas Rimhagen, Emil Ringh, Patrik Rugeland, Johan Rune, Joachim Sachs, Henrik Sahlin, Vidit Saxena, Nima Seifi, Yngve Selén, Eliane Semaan, Sachin Sharma, Cong Shi, Johan Sköld, Magnus Stattin, Anders Stjernman, Dennis Sundman, Lars Sundström, Miurel Isabel Tercero Vargas, Claes Tidestav, Sibel Tombaz, Johan Torsner, Hugo Tullberg, Jari Vikberg, Peter von Wrycza, Thomas Walldeen, Anders Wallén, Pontus Wallentin, Hai Wang, Ke Wang Helmersson, Jianfeng Wang, Yi-Pin Eric Wang, Niclas Wiberg, Emma Wittenmark, Osman Nuri Can Yilmaz, Ali Zaidi, Zhan Zhang, Zhang Zhang, Yanli Zheng
  • Publication number: 20220271786
    Abstract: There is provided a radio transceiver device. The radio transceiver device comprises an antenna. The radio transceiver device further comprises a signal processing module. The radio transceiver device further comprises a receiver chain configured to receive a first signal. The receiver chain extends from the antenna to the signal processing module and at least comprises an analog-to-digital converter (ADC), and is thereby configured to receive a first signal from the antenna and provide the first signal to the signal processing module after application of analog-to-digital conversion in the ADC to the first signal. The radio transceiver device further comprises a transmitter chain. The transmitter chain extends from the signal processing module to the antenna and at least comprises a digital-to-analog converter (DAC), and is thereby configured to receive a second signal from the signal processing module and provide the second signal to the antenna after application of digital-to-analog conversion in the DAC.
    Type: Application
    Filed: June 28, 2019
    Publication date: August 25, 2022
    Applicant: Telefonaktiebolaget LM Ericsson (publ)
    Inventors: Sven JACOBSSON, Lise AABEL, Ibrahim Can SEZGIN, Christian FAGER, Mikael COLDREY
  • Publication number: 20220239350
    Abstract: There is provided mechanisms for beamformed transmission using a precoder. A method is performed by a radio transceiver device. The radio transceiver device comprises hardware. The hardware impacts transmission of signals from the radio transceiver device. The method comprises acquiring channel conditions of a radio propagation channel between the radio transceiver device and at least one other radio transceiver device. The method comprises determining a precoder, in form of a linear precoding matrix, for beamformed transmission towards the at least one other radio transceiver device. The precoder is determined according to the channel conditions and a model of how the hardware impacts the transmission of signals from the radio transceiver device. The method comprises transmitting, using the precoder, a signal towards the at least one other radio transceiver device.
    Type: Application
    Filed: May 17, 2019
    Publication date: July 28, 2022
    Applicant: Telefonaktiebolaget LM Ericsson (publ)
    Inventors: Sven JACOBSSON, Sina REZAEI AGHDAM, Thomas ERIKSSON, Hamed FARHADI, Ulf GUSTAVSSON
  • Publication number: 20220231750
    Abstract: A link adaptation method is disclosed for a transmitter node configured for spatial multiplexing of signals into streams and for transmission of spatially multiplexed streams over a forward channel, wherein each stream is intended for a receiver node. The method comprises selecting a transmission pre-coding setting for at least one of the spatially multiplexed streams based on an acquired channel estimate of the forward channel, estimating a forward channel disturbance component, wherein the forward channel disturbance component includes signal distortion for the forward channel caused by at least one hardware component of the transmitter node and/or the receiver node, and performing link adaptation for at least one of the spatially multiplexed streams based on the selected transmission pre-coding setting and the estimated forward channel disturbance component. Corresponding apparatus, transmitter node and computer program product are also disclosed.
    Type: Application
    Filed: June 12, 2019
    Publication date: July 21, 2022
    Applicant: Telefonaktiebolaget LM Ericsson (publ)
    Inventors: Hamed FARHADI, Ulf GUSTAVSSON, Sven JACOBSSON
  • Patent number: 11381445
    Abstract: Methods and apparatus in a fifth-generation wireless communications network, including an example method, in a wireless device, that includes determining a reporting quality threshold for a parameter related to channel state information (CSI); performing a measurement for each of a plurality of beams from a first predetermined set of beams for evaluation; evaluating the measurement for each of the plurality of beams against the reporting quality threshold; discontinuing the performing and evaluating of measurements in response to determining that the reporting quality threshold is met for one of the beams, such that one or more beams in the first predetermined set of beams are not measured and evaluated; and reporting, to the wireless communications network, CSI for the one of the beams.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: July 5, 2022
    Assignee: TELEFONAKTIEBOLAGET LM ERICSSON (PUBL)
    Inventors: Stefan Parkvall, Janne Peisa, Gunnar Mildh, Robert Baldemair, Stefan Wager, Jonas Kronander, Karl Werner, Richard Abrahamsson, Ismet Aktas, Peter Alriksson, Junaid Ansari, Shehzad Ali Ashraf, Henrik Asplund, Fredrik Athley, Håkan Axelsson, Joakim Axmon, Johan Axnäs, Kumar Balachandran, Gunnar Bark, Jan-Erik Berg, Andreas Bergström, Håkan Björkegren, Nadia Brahmi, Cagatay Capar, Anders Carlsson, Andreas Cedergren, Mikael Coldrey, Icaro L. J. da Silva, Erik Dahlman, Ali El Essaili, Ulrika Engström, Mårten Ericson, Erik Eriksson, Mikael Fallgren, Rui Fan, Gabor Fodor, Pål Frenger, Jonas Fridén, Jonas Fröberg Olsson, Anders Furuskär, Johan Furuskog, Virgile Garcia, Ather Gattami, Fredrik Gunnarsson, Ulf Gustavsson, Bo Hagerman, Fredrik Harrysson, Ning He, Martin Hessler, Kimmo Hiltunen, Songnam Hong, Dennis Hui, Jörg Huschke, Tim Irnich, Sven Jacobsson, Niklas Jaldén, Simon Järmyr, Zhiyuan Jiang, Martin Johansson, Niklas Johansson, Du Ho Kang, Eleftherios Karipidis, Patrik Karlsson, Ali S. Khayrallah, Caner Kilinc, Göran N. Klang, Sara Landström, Christina Larsson, Gen Li, Bo Lincoln, Lars Lindbom, Robert Lindgren, Bengt Lindoff, Fredrik Lindqvist, Jinhua Liu, Thorsten Lohmar, Qianxi Lu, Lars Manholm, Ivana Maric, Jonas Medbo, Qingyu Miao, Reza Moosavi, Walter Müller, Elena Myhre, Johan Nilsson, Karl Norrman, Bengt-Erik Olsson, Torgny Palenius, Sven Petersson, Jose Luis Pradas, Mikael Prytz, Olav Queseth, Pradeepa Ramachandra, Edgar Ramos, Andres Reial, Thomas Rimhagen, Emil Ringh, Patrik Rugeland, Johan Rune, Joachim Sachs, Henrik Sahlin, Vidit Saxena, Nima Seifi, Yngve Selén, Eliane Semaan, Sachin Sharma, Cong Shi, Johan Sköld, Magnus Stattin, Anders Stjernman, Dennis Sundman, Lars Sundström, Miurel Isabel Tercero Vargas, Claes Tidestav, Sibel Tombaz, Johan Torsner, Hugo Tullberg, Jari Vikberg, Peter Von Wrycza, Thomas Walldeen, Anders Wallén, Pontus Wallentin, Hai Wang, Ke Wang Helmersson, Jianfeng Wang, Yi-Pin Eric Wang, Niclas Wiberg, Emma Wittenmark, Osman Nuri Can Yilmaz, Ali Zaidi, Zhan Zhang, Zhang Zhang, Yanli Zheng
  • Publication number: 20220133739
    Abstract: Methods for treating and/or protecting against acute liver failure and other hepatotoxicities in an individual employ a combination of a first active agent comprising N-acetylcysteine and a second active agent comprising a manganese complex selected from the group consisting of (i) a calcium manganese mixed metal complex of N,N?-bis-(pyridoxal-5-phosphate)-ethylenediamine-N,N?-diacetic acid (DPDP) having a molar ratio of calcium to manganese in a range of from 1 to 10, or a pharmaceutically acceptable salt thereof, (ii) a mixture of manganese DPDP (MnDPDP), or a pharmaceutically acceptable salt thereof, and a non-manganese-containing DPDP compound, or (iii) a mixture of manganese pyridoxyl ethylenediamine (MnPLED), or a pharmaceutically acceptable salt thereof, and a non-manganese-containing pyridoxyl ethylenediamine (PLED) compound.
    Type: Application
    Filed: January 14, 2022
    Publication date: May 5, 2022
    Inventors: Jacques NÄSSTRÖM, Sven JACOBSSON, Dennis HENRIKSEN, James VAN ALSTINE
  • Patent number: 11260060
    Abstract: Methods, formulations and kits for treating and/or protecting against acute liver failure and other hepatotoxicities in an individual employ a combination of a first active agent which replenishes, or decreases a loss of, functional glutathione in the individual, and a second active agent comprising a manganese complex selected from the group consisting of (i) a calcium manganese mixed metal complex of N,N?-bis-(pyridoxal-5-phosphate)-ethylenediamine-N,N?-diacetic acid (DPDP) having a molar ratio of calcium to manganese in a range of from 1 to 10, or a pharmaceutically acceptable salt thereof, (ii) a mixture of manganese DPDP (MnDPDP), or a pharmaceutically acceptable salt thereof, and a non-manganese-containing DPDP compound, or (iii) a mixture of manganese pyridoxyl ethylenediamine (MnPLED), or a pharmaceutically acceptable salt thereof, and a non-manganese-containing pyridoxyl ethylenediamine (PLED) compound.
    Type: Grant
    Filed: January 10, 2017
    Date of Patent: March 1, 2022
    Assignee: EGETIS THERAPEUTICS AB
    Inventors: Jacques Näsström, Sven Jacobsson, Dennis Henriksen, James Van Alstine