Patents by Inventor Sven Krugener

Sven Krugener has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF A BIRNAVIRUS ALONE OR IN COMBINATION THERAPY FOR THE TREATMENT OF CANCER
    Publication number: 20240299476
    Abstract: The present invention relates to a birnavirus for use in the treatment or prevention of cancer. Further, the present invention relates to a combination comprising at least one birnavirus and at least one further active agent for use in the treatment or prevention of cancer. Furthermore, the present invention relates to a pharmaceutical composition comprising the birnavirus or the combination for use in the treatment or prevention of cancer.
    Type: Application
    Filed: December 15, 2021
    Publication date: September 12, 2024
    Inventors: Tibor Bakacs, Volker Sandig, Shimon Slavin, Sven Krugener, Wolfgang W. Renz, Imre Kovesdi, Alexander Karlas, Deborah Horn
  • Method for purifying an enveloped virus
    Patent number: 11999975
    Abstract: The present invention relates to a method for purifying an enveloped virus. The present invention further relates to an enveloped virus or a plurality of enveloped viruses obtainable by said method.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: June 4, 2024
    Assignee: ProBioGen AG
    Inventors: Volker Sandig, Michael Mühle, Sven Krügener
  • USE OF A BIRNAVIRUS ALONE OR IN COMBIMATION THERAPY FOR THE TREATMENT OF A DISEASE CAUSED BY A NIDOVIRUS
    Publication number: 20240024390
    Abstract: The present invention relates to a birnavirus for use in the treatment of a disease caused by a nidovirus. Further, the present invention relates to a combination comprising at least one birnavirus and at least one further active agent for use in the treatment of a disease caused by a nidovirus. Furthermore, the present invention relates to a pharmaceutical composition comprising the birnavirus or the combination for use in the treatment of a disease caused by a nidovirus.
    Type: Application
    Filed: December 21, 2020
    Publication date: January 25, 2024
    Inventors: Imre Kovesdi, Tibor Bakacs, Volker Sandig, Shimon Slavin, Deborah Horn, Alexander Karlas, Sven Krugener
  • HYPERACTIVE TRANSPOSONS AND TRANSPOSASES
    Publication number: 20230257778
    Abstract: The present invention relates to a polypeptide comprising a piggyBac transposase or a fragment or a derivative thereof having transposase function comprising at least one amino acid substitution. Further, the present invention relates to a transposable element comprising a piggyBac or piggyBac-like left repeat sequence and left internal repeat sequence, wherein the left internal repeat sequence comprises at least one nucleotide modification. Furthermore, the present invention relates to a kit comprising the above transposase and/or transposable element. In addition, the present invention relates to a targeting system comprising the above transposase and/or transposable element.
    Type: Application
    Filed: July 17, 2020
    Publication date: August 17, 2023
    Inventors: VOLKER SANDIG, Sven Krügener, Thomas Rose
  • Method For Purifying An Enveloped Virus
    Publication number: 20220267738
    Abstract: The present invention relates to a method for purifying an enveloped virus. The present invention further relates to an enveloped virus or a plurality of enveloped viruses obtainable by said method.
    Type: Application
    Filed: June 27, 2019
    Publication date: August 25, 2022
    Applicant: ProBioGen AG
    Inventors: Volker SANDIG, Michael MÜHLE, Sven KRÜGENER
  • TRANSPOSASE WITH ENHANCED INSERTION SITE SELECTION PROPERTIES
    Publication number: 20220090142
    Abstract: The present invention relates to a polypeptide comprising a transposase and at least one heterologous chromatin reader element (CRE). Further, the present invention relates to a polynucleotide encoding the polypeptide. Furthermore, the present invention relates to a vector comprising the polynucleotide. In addition, the present invention relates to a kit comprising a transposase and at least one heterologous chromatin reader element (CRE).
    Type: Application
    Filed: February 13, 2019
    Publication date: March 24, 2022
    Inventors: Sven Krügener, Thomas Rose, Volker Sandig, Karsten Winkler