Patents by Inventor Sven Moller-Tank

Sven Moller-Tank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR EXPRESSING FACTOR IX FOR HEMOPHILIA B THERAPY
    Publication number: 20230149563
    Abstract: Nucleic acid constructs and compositions that allow insertion of a FIX coding sequence into a target genomic locus such as an endogenous ALB locus and/or expression of the FIX coding sequence are provided. The nucleic acid constructs and compositions can be used in methods of introducing a F9 nucleic acid into a cell, methods of integration of a F9 nucleic acid into a target genomic locus, methods of expression of FIX in a cell, and in methods of treating hemophilia B or FIX deficiency in a subject.
    Type: Application
    Filed: October 27, 2022
    Publication date: May 18, 2023
    Inventors: Leah Sabin, Christos Kyratsous, Evangelos Pefanis, Sven Moller-Tank, Joseph Katakowski, Andrew Baik, Katherine Cygnar, Poulami Samai, Philip Calafati
  • MODIFIED VIRAL PARTICLES AND USES THEREOF
    Publication number: 20220241430
    Abstract: Provided herein are compositions and methods for adapting adeno-associated virus (AAV) particles comprising capsids of non-primate animal AAV, remote AAV, or a combination thereof. AAV adapted accordingly may be a viable gene therapy platform for the treatment of a patient in need thereof, and may be particularly useful in patients excluded from current treatment modalities involving current therapeutic AAV particles due to their high titer of antibodies against the current therapeutic AAV particles.
    Type: Application
    Filed: May 22, 2020
    Publication date: August 4, 2022
    Inventors: Leah Sabin, Christos Kyratsous, Sven Moller-Tank
  • METHODS AND COMPOSITIONS FOR ENGINEERED ASSEMBLY ACTIVATING PROTEINS (EAAPS)
    Publication number: 20210147487
    Abstract: The present invention relates to compositions and methods comprising an engineered assembly activating protein (EAAP).
    Type: Application
    Filed: April 4, 2019
    Publication date: May 20, 2021
    Inventors: Aravind Asokan, Sven Moller-Tank, Long Ping Victor Tse