Patents by Inventor Sven O. / gren

Sven O. / gren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5240957
    Abstract: Novel therapeutically active compounds of the formula ##STR1## wherein Z.sup.i, being Z.sup.1, Z.sup.2 or Z.sup.3, is the same or different and selected among OH, OR.sup.1, NH.sub.2, NR.sub.2.sup.4, NHR.sup.4, SH, SR.sup.4 and OR.sup.4 wherein R.sup.1 is a formyl group, an acyl group, an alkoxycarbonyl group or a mono- or dialkylcarbamoyl group and R.sup.4 is a lower alkyl group,R.sup.2 is a hydrogen, a halogen, a lower alkyl or a lower trifluoroalkyl group,R.sup.3 is a hydrogen atom, a lower alkyl group, an alkenyl group, an alkynyl group or a phenyl group, which phenyl group could optionally be substituted by one or more of fluoro, chloro, bromo, trifluoromethyl, methyl, ethyl, methoxy or ethoxy in the ortho, meta or para positions, or optionally substituted by methylenedioxy, provided that at least one of Z.sup.1, Z.sup.2 and Z.sup.3 is a group OR.sup.4 and further provided that when Z.sup.2 is OH or NH.sub.2, Z.sup.1 is NR.sub.2.sup.4, NHR.sup.4, SH, SR.sup.4 or OR.sup.
    Type: Grant
    Filed: October 29, 1990
    Date of Patent: August 31, 1993
    Assignee: Astra Lakemedel Akteibolag
    Inventors: Karl S. Bengtsson, Thomas Hogberg, Lars G. Johansson, Tomas DePaulis, Hans E. P. Strom, Marianne E. Widman, Sven O. gren
  • Patent number: 4937260
    Abstract: Novel therapeutically active compounds of the formula ##STR1## wherein R is a straight or branched alkyl group with 6-18 carbon atoms, R.sup.1 is hydrogen, chlorine, bromine or an alkyl group with 1-3 carbon atoms and R.sup.2 is chlorine, bromine or an alkyl group with 1-3 carbon atoms; or a physiologically acceptable salt or an optical isomer thereof, methods and intermediates for their preparation, pharmaceutical preparations containing them and methods for their therapeutical use.
    Type: Grant
    Filed: January 27, 1988
    Date of Patent: June 26, 1990
    Assignee: Astra Lakemedal Aktiebolag
    Inventors: Tomas De Paulis, Sten I. Ramsby, Sven O. gren
  • Patent number: 4789683
    Abstract: Novel therapeutically active compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and each represents a hydrogen atom, a halogen atom, a cyano group, a lower alkyl group or an acyl group, R.sup.3 is a lower alkyl group; an alkenyl group; or a benzyl group optionally substituted with fluorine, chlorine, bromine, trifluoromethyl, lower alkyl or lower alkoxy, A.sup.1 and A.sup.2 are the same or different and each represents a hydrogen atom, a lower alkyl group, an acyl group, an alkoxycarbonyl group or a dialkylcarbamyl group, provided that when A.sup.1 and A.sup.2 are the same lower alkyl group and R.sup.3 is ethyl, R.sup.1 or R.sup.2 or both are selected among cyano, lower alkyl and acyl; or a physiologically acceptable salt or optical isomers thereof, methods for their preparation, pharmaceutical preparations containing the compounds and methods for their therapeutical use.
    Type: Grant
    Filed: January 8, 1985
    Date of Patent: December 6, 1988
    Assignee: Astra Lakemedel Aktiebolag
    Inventors: Gosta L. Florvall, Jan O. G. Lundstrom, Sten I. Ramsby, Sven O. gren
  • Patent number: 4331684
    Abstract: A compound of the general formula ##STR1## and pharmaceutically acceptable salts thereof, in which formula the groups R.sup.0 are the same or different and are selected from the group consisting of hydrogen, halogen, alkyl having 1, 2 or 3 carbon atoms, and alkoxy having 1, 2 or 3 carbon atoms; R.sup.1 and R.sup.2 are methyl; R.sup.3 and R.sup.4 are the same or different and are hydrogen or an alkyl group having 1, 2 or 3 carbon atoms; and n is 0. Pharmaceutical preparations containing these compounds are useful for treatment of depressive disorders.
    Type: Grant
    Filed: May 28, 1980
    Date of Patent: May 25, 1982
    Assignee: Astra Lakemedel Aktiebolag
    Inventors: Ulf H. A. Lindberg, Svante B. Ross, Seth-Olov Thorberg, Sven O. gren
  • Patent number: 4237311
    Abstract: A compound of the general formula ##STR1## and pharmaceutically acceptable salts thereof, in which formula the groups R.sup.o are the same or different and are selected from the group consisting of hydrogen, halogen, alkyl having 1, 2 or 3 carbon atoms, and alkoxy having 1, 2 or 3 carbon atoms; R.sup.1 is hydrogen, methyl or ethyl; R.sup.2 is methyl or ethyl; R.sup.3 and R.sup.4 are the same or different and are hydrogen or an alkyl group having 1, 2 or 3 carbon atoms; and n is 0, 1 or 2. Pharmaceutical preparations containing these compounds are useful for treatment of depressive disorders.
    Type: Grant
    Filed: August 10, 1978
    Date of Patent: December 2, 1980
    Assignee: Astra Lakemedel Aktiebolag
    Inventors: Ulf M. A. Lindberg, Svante B. Ross, Seth-Olov Thorberg, Sven O. / gren