Patents by Inventor Sven T. Pleger

Sven T. Pleger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tissue specific gene therapy treatment
    Patent number: 8383601
    Abstract: The invention provides nucleic acid segments, compositions and methods for the treatment of heart failure, vascular dysfunction, endothelial dysfunction, diabetes, [Ca2+]i regulation and NO synthase dysfunction. Adeno-associated and adenovirus are used as gene delivery vectors for the nucleic acid segments to product long term over-expression of S100A1, a small calcium sensing protein associated with the disclosed ailments and dysfunctions.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: February 26, 2013
    Assignee: Thomas Jefferson University
    Inventors: Walter J. Koch, Patrick Most, Sven T. Pleger, Joseph E. Rabinowitz
  • TISSUE SPECIFIC GENE THERAPY TREATMENT
    Publication number: 20100190840
    Abstract: The invention provides nucleic acid segments, compositions and methods for the treatment of heart failure, vascular dysfunction, endothelial dysfunction, diabetes, [Ca2+]i regulation and NO synthase dysfunction. Adeno-associated and adenovirus are used as gene delivery vectors for the nucleic acid segments to product long term over-expression of S100A1, a small calcium sensing protein associated with the disclosed ailments and dysfunctions.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 29, 2010
    Applicant: THOMAS JEFFERSON UNIVERSITY
    Inventors: Walter J. Koch, Patrick Most, Sven T. Pleger, Joseph E. Rabinowitz