Patents by Inventor Svend K. Petersen-Mahrt

Svend K. Petersen-Mahrt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130059931
    Abstract: The invention is directed to a cell comprising a nucleic acid encoding an Activation Induced Deaminase (AID) polypeptide, a fusion protein comprising an AID polypeptide, and methods of using a nucleic acid encoding an AID polypeptide.
    Type: Application
    Filed: September 7, 2012
    Publication date: March 7, 2013
    Applicant: MEDICAL RESEARCH COUNCIL
    Inventors: Svend K. Petersen-Mahrt, Reuben Harris, Michael S. Neuberger, Rupert Christopher Landsdowne Beale
  • Patent number: 8288160
    Abstract: The invention is directed to a cell comprising a nucleic acid encoding an Activation Induced Deaminase (AID) polypeptide, a fusion protein comprising an AID polypeptide, and methods of using a nucleic acid encoding an AID polypeptide.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: October 16, 2012
    Assignee: Medical Research Council
    Inventors: Svend K. Petersen-Mahrt, Reuben Harris, Michael Samuel Neuberger, Rupert Christopher Landsdowne Beale
  • Publication number: 20110136922
    Abstract: The invention is directed to a cell comprising a nucleic acid encoding an Activation Induced Deaminase (AID) polypeptide, a fusion protein comprising an AID polypeptide, and methods of using a nucleic acid encoding an AID polypeptide.
    Type: Application
    Filed: October 25, 2010
    Publication date: June 9, 2011
    Applicant: MEDICAL RESEARCH COUNCIL
    Inventors: Svend K. Petersen-Mahrt, Reuben Harris, Michael S. Neuberger, Rupert Christopher Landsdowne Beale
  • Patent number: 7820442
    Abstract: The present invention identifies that the expression of Activation Induced Deaminase (AID) or its homologues in cells confers a mutator phenotype and thus provides a method for generating diversity in a gene or gene product as well as cell lines capable of generating diversity in defined gene products. The invention also provides methods of modulating a mutator phenotype by modulating AID expression or activity.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: October 26, 2010
    Assignee: Medical Research Council
    Inventors: Svend K. Petersen-Mahrt, Reuben Harris, Michael Samuel Neuberger, Rupert Christopher Landsdowne Beale