Patents by Inventor Svetlana A. Dubley

Svetlana A. Dubley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Miniaturized reaction vessel system, method for performing site-specific biochemical reactions and affinity fractionation for use in DNA sequencing
    Patent number: 6143499
    Abstract: A method for fractionating and sequencing DNA via affinity interaction is provided comprising contacting cleaved DNA to a first array of oligonucleotide molecules to facilitate hybridization between said cleaved DNA and the molecules; extracting the hybridized DNA from the molecules; contacting said extracted hybridized DNA with a second array of oligonucleotide molecules, wherein the oligonucleotide molecules in the second array have specified base sequences that are complementary to said extracted hybridized DNA; and attaching labeled DNA to the second array of oligonucleotide molecules, wherein the labeled re-hybridized DNA have sequences that are complementary to the oligomers.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: November 7, 2000
    Assignee: University of Chicago
    Inventors: Andrei Darievich Mirzabekov, Yuri Petrovich Lysov, Svetlana A. Dubley
  • Method for performing site-specific affinity fractionation for use in DNA sequencing
    Patent number: 5905024
    Abstract: A method for fractionating and sequencing DNA via affinity interaction is provided comprising contacting cleaved DNA to a first array of oligonucleotide molecules to facilitate hybridization between said cleaved DNA and the molecules; extracting the hybridized DNA from the molecules; contacting said extracted hybridized DNA with a second array of oligonucleotide molecules, wherein the oligonucleotide molecules in the second array have specified base sequences that are complementary to said extracted hybridized DNA; and attaching labeled DNA to the second array of oligonucleotide molecules, wherein the labeled re-hybridized DNA have sequences that are complementary to the oligomers.
    Type: Grant
    Filed: December 17, 1996
    Date of Patent: May 18, 1999
    Assignee: University of Chicago
    Inventors: Andrei Darievich Mirzabekov, Yuri Petrovich Lysov, Svetlana A. Dubley