Patents by Inventor Svetlana GINGIS-VELITSKI

Svetlana GINGIS-VELITSKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
    Patent number: 10730925
    Abstract: A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: August 4, 2020
    Assignee: Protalix Ltd.
    Inventors: Yoseph Shaaltiel, Uri Hanania, Tali Kizhner, Tami Ariel, Svetlana Gingis-Velitski
  • CHIMERIC POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
    Publication number: 20180327476
    Abstract: A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
    Type: Application
    Filed: July 26, 2018
    Publication date: November 15, 2018
    Applicant: Protalix Ltd.
    Inventors: Yoseph SHAALTIEL, Uri HANANIA, Tali KIZHNER, Tami ARIEL, Svetlana GINGIS-VELITSKI
  • CHIMERIC POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
    Publication number: 20180291084
    Abstract: A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
    Type: Application
    Filed: June 13, 2018
    Publication date: October 11, 2018
    Applicant: Protalix Ltd.
    Inventors: Yoseph SHAALTIEL, Uri HANANIA, Tali KIZHNER, Tami ARIEL, Svetlana GINGIS-VELITSKI, Myriam GOLEMBO
  • Use of plant cells expressing a TNFalpha polypeptide inhibitor in therapy
    Patent number: 10087232
    Abstract: A method of treating a TNF Alpha associated medical condition selected from the group consisting of obesity, metabolic syndrome, diabetes and a liver disease or disorder is provided. The method comprising enterally administering to a subject in need thereof a therapeutically effective amount of plant cells expressing a TNF Alpha polypeptide inhibitor, thereby treating the TNF Alpha associated medical condition.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: October 2, 2018
    Assignees: Protalix Ltd., Hadasit Medical Research Services and Development Ltd.
    Inventors: Yaron Ilan, Yoseph Shaaltiel, Uri Hanania, Tali Kizhner, Tami Ariel, Svetlana Gingis-Velitski
  • Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
    Patent number: 10000551
    Abstract: A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: June 19, 2018
    Assignee: Protalix Ltd.
    Inventors: Yoseph Shaaltiel, Uri Hanania, Tali Kizhner, Tami Ariel, Svetlana Gingis-Velitski, Myriam Golembo
  • CHIMERIC POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
    Publication number: 20160075754
    Abstract: A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
    Type: Application
    Filed: September 10, 2015
    Publication date: March 17, 2016
    Inventors: Yoseph SHAALTIEL, Uri Hanania, Tali Kizhner, Tami Ariel, Svetlana Gingis-Velitski, Myriam Golembo
  • CHIMERIC POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
    Publication number: 20160017020
    Abstract: A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising: (i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and (ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.
    Type: Application
    Filed: March 6, 2014
    Publication date: January 21, 2016
    Inventors: Yoseph SHAALTIEL, Uri HANANIA, Tali KIZHNER, Tami ARIEL, Svetlana GINGIS-VELITSKI
  • TNF alpha INHIBITOR POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
    Publication number: 20160017021
    Abstract: A plant produced TNF alpha polypeptide inhibitor is provided. Also provided are methods of generating and using same.
    Type: Application
    Filed: March 6, 2014
    Publication date: January 21, 2016
    Inventors: Yoseph SHAALTIEL, Uri HANANIA, Tali KIZHNER, Tami ARIEL, Svetlana GINGIS-VELITSKI
  • USE OF PLANT CELLS EXPRESSING A TNFalpha POLYPEPTIDE INHIBITOR IN THERAPY
    Publication number: 20160017019
    Abstract: A method of treating a TNF Alpha associated medical condition selected from the group consisting of obesity, metabolic syndrome, diabetes and a liver disease or disorder is provided. The method comprising enterally administering to a subject in need thereof a therapeutically effective amount of plant cells expressing a TNF Alpha polypeptide inhibitor, thereby treating the TNF Alpha associated medical condition.
    Type: Application
    Filed: March 6, 2014
    Publication date: January 21, 2016
    Inventors: Yaron ILAN, Yoseph SHAALTIEL, Uri HANANIA, Tali KIZHNER, Tami ARIEL, Svetlana GINGIS-VELITSKI