Abstract: The present invention relates to an improved process for the preparation of 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate (1/1) compound of formula-1a and its novel crystalline forms.

Abstract: The present invention relates to an improved process for the preparation of 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate (1/1) compound of formula-1a and its novel crystalline forms.

Abstract: Humidifier and related method embodiments and disclosed herein. A humidifier includes a base, a fluid column, a liquid tank, a lid, and a sealing assembly. The base has a liquid reservoir and is configured to generate mist. The fluid column is in fluid communication with the liquid reservoir and selectively in fluid communication with an ambient atmosphere to deliver mist to the ambient atmosphere. The liquid tank is coupled to the base and defines an interior volume. The liquid tank is configured to provide liquid to the liquid reservoir. The lid is selectively sealed to the fluid column and covers the liquid tank. The sealing assembly is coupled to the fluid column. The sealing assembly is configured, upon actuation, to both seal the fluid column from the ambient atmosphere to prevent delivery of mist to the ambient atmosphere and unseal the lid from the fluid column.

Abstract: Humidifier and related method embodiments are disclosed herein. A humidifier includes a liquid tank, a reservoir, a liquid atomizer, a valve, and a controller. The liquid tank defines a first interior volume, the reservoir is in liquid communication with the first interior volume, and the liquid atomizer is located in the reservoir. The valve is configured to actuate between a closed position and an opened position. The closed position prevents liquid communication between the first interior volume and the reservoir. The opened position allows liquid communication between the first interior volume and the reservoir. The controller is coupled to the valve and configured to selectively actuate the valve between the closed position and the opened position.