Patents by Inventor Swaroop Kumar Venkata Satya Vakkalanka

Swaroop Kumar Venkata Satya Vakkalanka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS
    Publication number: 20230234938
    Abstract: The present invention provides novel poly(ADP-ribose) polymerase (PARP) inhibitors, methods of preparing them, pharmaceutical compositions containing them and methods for the treatment, prevention and/or amelioration of PARP mediated diseases or disorders using them. In particular, the compounds described herein are useful for the treatment of carcinoma of the breast, ovarian cancer, carcinoma of the liver, carcinoma of the lung, small cell lung cancer, esophageal cancer, gall bladder cancer, pancreatic cancer and stomach cancer.
    Type: Application
    Filed: April 23, 2021
    Publication date: July 27, 2023
    Inventors: Debnath BHUNIYA, Srikant VISWANADHA, Gayatri Swaroop MERIKAPUDI, Swaroop Kumar Venkata Satya VAKKALANKA
  • PURINE DERIVATIVES AS SIK-3 INHIBITORS
    Publication number: 20230167116
    Abstract: The present invention relates to novel inhibitors of salt-inducible kinase-3 (SIK3), methods of preparing them, pharmaceutical compositions containing them and methods for the treatment and/or prevention of kinase mediated diseases or disorders using them.
    Type: Application
    Filed: May 11, 2021
    Publication date: June 1, 2023
    Inventors: Prashant K. BHAVAR, Srikant VISWANADHA, SRIDHAR VEERARAGHAVAN, Babu GOVINDARAJULU, Swaroop Kumar Venkata Satya VAKKALANKA
  • COMPOSITIONS COMPRISING A DHODH INHIBITOR FOR THE TREATMENT OF ACUTE MYELOID LEUKEMIA
    Publication number: 20220387362
    Abstract: The present invention relates to a method of treatment of acute myeloid leukemia (AML). In one embodiment, the present invention relates to a method of treating acute myeloid leukemia (AML) comprising administering to a subject in need thereof a dihydroorotate dehydrogenase (DHODH) inhibitor, alone in combination with at least one/ms-like tyrosine kinase 3 (FLT-3) inhibitor and/or a DNA polymerase inhibitor.
    Type: Application
    Filed: October 20, 2020
    Publication date: December 8, 2022
    Inventors: Srikant VISWANADHA, Swaroop Kumar Venkata Satya VAKKALANKA
  • PI3K protein kinase inhibitors
    Patent number: 11352359
    Abstract: The present disclosure provides novel compounds useful as PI3K protein kinase modulators, in particular as PI3K delta (?) and/or gamma (?) protein kinase modulators. The present disclosure also provides methods for preparing PI3K protein kinase modulators, pharmaceutical compositions containing them, and methods of treatment, prevention and/or amelioration of PI3K kinase mediated diseases or disorders with them.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: June 7, 2022
    Assignee: RHIZEN PHARMACEUTICALS AG
    Inventors: Prashant Kashinath Bhavar, Swaroop Kumar Venkata Satya Vakkalanka, Govindarajulu Babu
  • COMPOSITION AND METHOD FOR TREATING PERIPHERAL T-CELL LYMPHOMA AND CUTANEOUS T-CELL LYMPHOMA
    Publication number: 20200289520
    Abstract: The present invention relates to the use of a dual selective PI3K delta and gamma protein kinase inhibitor, such as (S)-2-(1-((9H-purin-6-yl)amino)propyl)-3-(3-fluorophenyl)-4H-chromen-4-one (Compound (A), also known as tenalisib) or a pharmaceutically acceptable salt thereof or a pharmaceutical composition containing such an inhibitor for the treatment of peripheral T-cell lymphoma (PTCL) and cutaneous T-cell lymphoma (CTCL). 34 139095.00100/115268675v.
    Type: Application
    Filed: December 5, 2018
    Publication date: September 17, 2020
    Inventor: Swaroop Kumar Venkata Satya Vakkalanka
  • NOVEL INHIBITORS OF GLUTAMINASE
    Publication number: 20160297761
    Abstract: The present disclosure provides compounds of formula (I) to (III) as glutaminase inhibitors, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of diseases or disorders involving glutamine
    Type: Application
    Filed: January 5, 2015
    Publication date: October 13, 2016
    Inventors: Prashant Kashinath BHAVAR, Swaroop Kumar Venkata Satya VAKKALANKA, Srikant VISWANADHA, Merikapudi Gayatri SWAROOP, Govindarajulu BABU
  • PI3K PROTEIN KINASE INHIBITORS, PARTICULARLY DELTA AND/OR GAMMA INHIBITORS
    Publication number: 20160207929
    Abstract: The present disclosure provides novel compounds useful as PI3K protein kinase modulators, in particular as PI3K delta (?) and/or gamma (?) protein kinase modulators. The present disclosure also provides methods for preparing PI3K protein kinase modulators, pharmaceutical compositions containing them, and methods of treatment, prevention and/or amelioration of PI3K kinase mediated diseases or disorders with them.
    Type: Application
    Filed: July 1, 2014
    Publication date: July 21, 2016
    Applicant: RHIZEN PHARMACEUTICALS SA
    Inventors: Prashant Kashinath Bhavar, Swaroop Kumar Venkata Satya Vakkalanka, Govindarajulu Babu