Patents by Inventor Swee Chuang Lim

Swee Chuang Lim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF STEVIOL GLYCOSIDE IN RECOMBINANT HOSTS
    Publication number: 20240026409
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Application
    Filed: August 16, 2023
    Publication date: January 25, 2024
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Production of steviol glycosides in recombinant hosts
    Patent number: 11821015
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: November 21, 2023
    Assignee: Evolva SA
    Inventors: Veronique Douchin, Swee Chuang Lim Hallwyl, Kim Olsson
  • Production of steviol glycoside in recombinant hosts
    Patent number: 11807888
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: November 7, 2023
    Assignee: EVOLVA SA
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • GENETICALLY MODIFIED HOST CELLS PRODUCING BENZYLISOQUINOLINE ALKALOIDS
    Publication number: 20230332195
    Abstract: The invention relate to genetically modified hosts cell comprising a pathway having enhanced production of one or more benzylisoquinoline alkaloids wherein the cell expresses heterologous insect genes encoding insect demethylases converting thebaine into northebaine, thebaine into oripavine, thebaine into nororipavine and/or oripavine into nororipavine.
    Type: Application
    Filed: October 9, 2020
    Publication date: October 19, 2023
    Applicant: RIVER STONE BIOTECH APS
    Inventors: Angela De CARVALHO, Swee Chuang Lim HALLWYL, Esben Halkjaer HANSEN, Jens HOUGHTON-LARSEN
  • Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20230212630
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: August 30, 2022
    Publication date: July 6, 2023
    Inventors: Helene Lunde Robertson, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicoline Rasmussen, Esben Halkjaer Hansen
  • PRODUCTION OF STEVIOL GLYCOSIDE IN RECOMBINANT HOSTS
    Publication number: 20230033436
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Application
    Filed: April 29, 2021
    Publication date: February 2, 2023
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • DELIVERY VEHICLE FOR IN SITU DELIVERING OF PHARMACEUTICAL AGENTS
    Publication number: 20220331377
    Abstract: The present invention relates to delivery vehicles comprising a system producing one or more active pharmaceutical ingredient (API) capable of preventing, treating and/or relieving one or more diseases in a mammal, wherein the vehicle comprises genetically modified microbial host cells suitable for administering to the mammal and wherein the vehicle is capable of delivering the produced API in situ of the location in the mammal body in need of preventing, treating and/or relieving the disease.
    Type: Application
    Filed: September 9, 2020
    Publication date: October 20, 2022
    Applicant: RIVER STONE BIOTECH ISG APS
    Inventors: Susanne Manuela GERMANN, Swee Chuang Lim HALLWYL, Jørgen HANSEN, Javier Porcayo LOZA
  • Production of steviol glycosides in recombinant hosts
    Patent number: 11466302
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: October 11, 2022
    Assignee: EVOLVA SA
    Inventors: Helene Lunde Robertsen, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicoline Rasmussen, Esben Halkjaer Hansen
  • Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20210403970
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: March 12, 2021
    Publication date: December 30, 2021
    Inventors: Veronique Douchin, Swee Chuang Lim Hallwyl, Kim Olsson
  • MICROBIAL CELL WITH IMPROVED IN VIVO CONVERSION OF THEBAINE/ORIPAVINE
    Publication number: 20210380995
    Abstract: A recombinant microbial host cell having improved in vivo conversion of reticuline and derivatives thereof (such as thebaine and/or oripavine) to relevant downstream opioids (such as neopinone, oripavine, northebaine, nororipavine or morphinone) and related compounds (such as heroin, morphine, codeine, thebaine, oripavine, oxycodone, hydrocodone, hydromorphone, oxymorphone, buprenorphine, naltrexone, naloxone or nalbuphine), wherein the microbial (such as fungal) host cell is heterologously expressing at least one functional transporter protein capable of transporting reticuline or a derivative thereof (such as thebaine and/or oripavine) and a heterologously expressed enzyme capable of acting upon reticuline or a derivative thereof. The invention also relates to uses of the microbial host cells and methods of making an opioid compound and/or opioid precursor compound and/or opioid derivative of interest.
    Type: Application
    Filed: October 10, 2019
    Publication date: December 9, 2021
    Inventors: Esben Halkjaer HANSEN, Swee Chuang Lim HALLWYL, Hussam Hassan NOUR-ELDIN, Zeinu Mussa BELEW
  • Production of steviol glycoside in recombinant hosts
    Patent number: 11041183
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: June 22, 2021
    Assignee: EVOLVA SA
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Production of steviol glycosides in recombinant hosts
    Patent number: 10982249
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: April 20, 2021
    Assignee: Evolva SA
    Inventors: Veronique Douchin, Swee Chuang Lim Hallwyl, Kim Olsson
  • Production of Steviol Glycosides in Recombinant Hosts
    Publication number: 20200392552
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: February 26, 2020
    Publication date: December 17, 2020
    Inventors: Helene Lunde Robertsen, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicoline Rasmussen, Esben Halkjaer Hansen
  • PRODUCTION OF STEVIOL GLYCOSIDES IN RECOMBINANT HOSTS
    Publication number: 20200291442
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: December 5, 2018
    Publication date: September 17, 2020
    Inventors: Veronique Douchin, Swee Chuang Lim Hallwyl
  • Production of steviol glycosides in recombinant hosts
    Patent number: 10612064
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: April 7, 2020
    Assignee: Evolva SA
    Inventors: Helene Lunde Robertson, Iben Nordmark Andersen, Adam Matthew Takos, Swee Chuang Lim Hallwyl, Francesca Ambri, Manuel Quiros Asensio, Michael Dalgaard Mikkelsen, Jens Houghton-Larsen, Veronique Douchin, Jane Dannow Dyekjaer, Simon Carlsen, Nina Nicoline Rasmussen, Esben Halkjaer Hansen
  • PRODUCTION OF STEVIOL GLYCOSIDE IN RECOMBINANT HOSTS
    Publication number: 20200017896
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Application
    Filed: June 7, 2019
    Publication date: January 16, 2020
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • Production of steviol glycoside in recombinant hosts
    Patent number: 10364450
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: July 30, 2019
    Assignee: EVOLVA SA
    Inventors: Kim Olsson, Ernesto Simon, Michael Dalgaard Mikkelsen, Simon Carlsen, Veronique Douchin, Swee Chuang Lim, Louis During
  • THE PRODUCTION OF STEVIOL GLYCOSIDES IN RECOMBINANT HOSTS
    Publication number: 20190203245
    Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.
    Type: Application
    Filed: April 13, 2017
    Publication date: July 4, 2019
    Inventors: Veronique Douchin, Swee Chuang Lim Hallwyl, Kim Olsson
  • COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF VANILLIN OR VANILLIN BETA-D-GLUCOSIDE
    Publication number: 20180251804
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductase thereby increasing the production of vanillin or vanillin beta-D-glucoside.
    Type: Application
    Filed: May 15, 2018
    Publication date: September 6, 2018
    Applicant: International flavors & Frangrances Inc.
    Inventors: Esben Halkjaer Hansen, Swee Chuang Lim Hallwyl, Klavs Riishede Hansen
  • Compositions and methods for the biosynthesis of vanillin or vanillin beta-D glucoside
    Patent number: 10066252
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductase thereby increasing the production of vanillin or vanillin beta-D-glucoside.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: September 4, 2018
    Assignee: INTERNATIONAL FLAVORS & FRAGRANCES INC.
    Inventors: Esben Halkjaer Hansen, Swee Chuang Lim Hallwyl, Klavs Riishede Hansen