Patents by Inventor Sybille Muller

Sybille Muller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for reducing T cell-mediated cytotoxicity in HIV using anti-idiotypic antibody
    Patent number: 6146627
    Abstract: The present invention provides an anti-idiotypic antibody having specific reactivity with an idiotope common to more than one type of anti-HIV-1 antibody, and having no specific reactivity with non-HIV-1 antibodies. The present invention provides methods of diagnosis, monitoring and treatment of HIV-related diseases through the use of this antibody or related compounds.
    Type: Grant
    Filed: December 14, 1998
    Date of Patent: November 14, 2000
    Assignee: Sidney Kimmel Cancer Center
    Inventors: Sybille Muller, Haitao Wang
  • Variable heavy and light chain regions of murine monoclonal antibody 1F7
    Patent number: 6057421
    Abstract: The amino acid sequences of variable heavy and variable light domains of murine monoclonal antibody 1F7 are reported. Methods of use for products containing these sequences in the diagnosis and the treatment of HIV infection and AIDS are also described.
    Type: Grant
    Filed: December 3, 1997
    Date of Patent: May 2, 2000
    Assignee: Immpheron, Inc.
    Inventors: Sybille Muller, Heinz Kohler
  • Anti-idiotypic antibody and its use in diagnosis and therapy in HIV-related disease
    Patent number: 5849583
    Abstract: The present invention provides an anti-idiotypic antibody having specific reactivity with an idiotope common to more than one type of anti-HIV-1 antibody, and having no specific reactivity with non-HIV-1 antibodies. The present invention provides methods of diagnosis, monitoring and treatment of HIV-related diseases through the use of this antibody or related compounds.
    Type: Grant
    Filed: August 20, 1993
    Date of Patent: December 15, 1998
    Assignee: Sidney Kimmel Cancer Center
    Inventors: Sybille Muller, Haitao Wang