Patents by Inventor Sydney A. BARNES

Sydney A. BARNES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • B7H3 SINGLE DOMAIN ANTIBODIES AND THERAPEUTIC COMPOSITIONS THEREOF
    Publication number: 20230124851
    Abstract: Provided herein are binding polypeptides that specifically bind B7H3. More specifically, provided herein are fusion proteins, including multivalent and/or multispecific constructs and chimeric antigen receptors, that bind B7H3. Also provided are pharmaceutical compositions containing the polypeptides, nucleic acid molecules encoding the polypeptides and vectors and cells thereof, and methods of use and uses of the provided B7H3 binding polypeptides for treating diseases and conditions, such as cancer.
    Type: Application
    Filed: October 9, 2019
    Publication date: April 20, 2023
    Applicant: Inhibrx, lnc.
    Inventors: Brendan P. ECKELMAN, Michael D. KAPLAN, Katelyn M. WILLIS, Kyle S. JONES, Angelica N. SANABRIA, Sydney A. BARNES, Margaret E. HAERR, John C. TIMMER
  • DLL3 SINGLE DOMAIN ANTIBODIES AND THERAPEUTIC COMPOSITIONS THEREOF
    Publication number: 20210380679
    Abstract: Provided herein are binding polypeptides that specifically bind DLL3. More specifically, provided herein are fusion proteins, including multivalent and/or multispecific contracts and chimeric antigen receptors, that bind DLL3. Also provided are pharmaceutical compositions containing the polypeptides, nucleic acid molecules encoding the polypeptides and vectors and cells thereof, and methods of use and uses of the provided DLL3 binding polypeptides for treating diseases and conditions, such as cancer.
    Type: Application
    Filed: October 9, 2019
    Publication date: December 9, 2021
    Applicant: Inhibrx, Inc.
    Inventors: Brendan P. ECKELMAN, Michael D. KAPLAN, Kateiyn M. WILLIS, Raiay A. PANDIT, Angelica N. SANABRIA, Sydney A. BARNES, Margaret E. HAERR, John C. TIMMER
  • 5T4 SINGLE DOMAIN ANTIBODIES AND THERAPEUTIC COMPOSITIONS THEREOF
    Publication number: 20210340273
    Abstract: Provided herein arm binding polypeptides that specifically bind 5T4. More specifically, provided herein are fusion proteins, including multivalent and/or multispecific constructs and chimeric antigen receptors, that bind 5T4. Also provided are pharmaceutical compositions containing the polypeptides, nucleic acid molecules encoding the polypeptides and vectors and cells thereof, and methods of use and uses of the provided 5T4 binding polypeptides for treating diseases and conditions, such as cancer.
    Type: Application
    Filed: October 9, 2019
    Publication date: November 4, 2021
    Applicant: Inhlbrx, inc.
    Inventors: John C. TIMMER, Michael D. KAPLAN, Katelyn M. WILLIS, Raiay A. PANDIT, Angelica N. SANABRIA, Sydney A. BARNES, Margaret E. HAERR, Brendan P. ECKELMAN, Rutger H. JACKSON