Patents by Inventor Sydney David Finkelstein

Sydney David Finkelstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11143657
    Abstract: The application relates to a method of a predicting the presence of invasive pancreatic cancer or high grade dysplasia, pre-cancerous pancreatic states and non-neoplastic conditions comprising detailed molecular analysis incorporating DNA quality and quantity, K-ras mutational analysis and a broad spectrum of tumor suppressor gene linked microsatellite LOH. Methods of diagnosing, determining prognosis of and determining a course of treatment for pancreatic cancer or high grade dysplasia, pre-cancerous pancreatic states and non-neoplastic conditions are also provided.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: October 12, 2021
    Assignee: Interpace Diagnostics Corporation
    Inventors: Sydney David Finkelstein, Patricia Swalsky
  • Publication number: 20200249236
    Abstract: Disclosed herein are methods of accurately measuring carcinoembryonic antigen in a biological sample and methods of identifying and treating a mucinous cyst in a subject.
    Type: Application
    Filed: September 3, 2019
    Publication date: August 6, 2020
    Inventors: Sydney David Finkelstein, Sara Ann Jackson, Jamie Michelle Bleicher, Eric Matthew Gayle Ellsworth, Dennis Morgan Smith, JR.
  • Publication number: 20200035324
    Abstract: Disclosed herein are methods for treating Barrett's metaplasia and esophageal adenocarcinoma and methods for determining mutational load as a predictor of the risk of disease progression from Barrett's metaplasia to esophageal adenocarcinoma.
    Type: Application
    Filed: February 26, 2019
    Publication date: January 30, 2020
    Inventors: Eric Matthew Gayle Ellsworth, Sydney David Finkelstein, Sara Ann Jackson, Brendan Corcoran, Dennis Morgan Smith
  • Patent number: 10444239
    Abstract: Disclosed herein are methods of accurately measuring carcinoembryonic antigen in a biological sample and methods of identifying and treating a mucinous cyst in a subject.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: October 15, 2019
    Assignee: INTERPACE DIAGNOSTICS CORPORATION
    Inventors: Sydney David Finkelstein, Sara Ann Jackson, Jamie Michelle Bleicher, Eric Matthew Gayle Ellsworth, Dennis Morgan Smith, Jr.
  • Publication number: 20190292588
    Abstract: Disclosed herein are methods for treating Barrett's metaplasia and esophageal adenocarcinoma and methods for determining mutational load as a predictor of the risk of disease progression from Barrett's metaplasia to esophageal adenocarcinoma.
    Type: Application
    Filed: October 22, 2018
    Publication date: September 26, 2019
    Inventors: Eric Matthew Gayle Ellsworth, Sydney David Finkelstein, Sara Ann Jackson, Brendan Corcoran, Dennis Morgan Smith
  • Patent number: 10255410
    Abstract: Disclosed herein are methods for treating Barrett's metaplasia and esophageal adenocarcinoma and methods for determining mutational load as a predictor of the risk of disease progression from Barrett's metaplasia to esophageal adenocarcinoma.
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: April 9, 2019
    Assignee: INTERPACE DIAGNOSTICS CORPORATION
    Inventors: Eric Matthew Gayle Ellsworth, Sydney David Finkelstein, Sara Ann Jackson, Brendan Corcoran, Dennis Morgan Smith, Jr.
  • Publication number: 20190049452
    Abstract: The application relates to a method of a predicting the presence of invasive pancreatic cancer or high grade dysplasia, pre-cancerous pancreatic states and non-neoplastic conditions comprising detailed molecular analysis incorporating DNA quality and quantity, K-ras mutational analysis and a broad spectrum of tumor suppressor gene linked microsatellite LOH. Methods of diagnosing, determining prognosis of and determining a course of treatment for pancreatic cancer or high grade dysplasia, pre-cancerous pancreatic states and non-neoplastic conditions are also provided.
    Type: Application
    Filed: March 6, 2018
    Publication date: February 14, 2019
    Inventors: Sydney David Finkelstein, Patricia Swalsky
  • Patent number: 10131942
    Abstract: Disclosed herein are methods for treating Barrett's metaplasia and esophageal adenocarcinoma and methods for determining mutational load as a predictor of the risk of disease progression from Barrett's metaplasia to esophageal adenocarcinoma.
    Type: Grant
    Filed: July 30, 2013
    Date of Patent: November 20, 2018
    Assignee: INTERPACE DIAGNOSTICS CORPORATION
    Inventors: Eric Matthew Gayle Ellsworth, Sydney David Finkelstein, Sara Ann Jackson, Brendan Corcoran, Dennis Morgan Smith, Jr.
  • Publication number: 20170089907
    Abstract: Disclosed herein are methods of accurately measuring carcinoembryonic antigen in a biological sample and methods of identifying and treating a mucinous cyst in a subject.
    Type: Application
    Filed: May 6, 2016
    Publication date: March 30, 2017
    Inventors: Sydney David Finkelstein, Sara Ann Jackson, Jamie Michelle Bleicher, Eric Matthew Gayle Ellsworth, Dennis Morgan Smith, JR.
  • Patent number: 9341628
    Abstract: Disclosed herein are methods of accurately measuring carcinoembryonic antigen in a biological sample and methods of identifying and treating a mucinous cyst in a subject.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: May 17, 2016
    Assignee: INTERPACE DIAGNOSTICS CORPORATION
    Inventors: Sydney David Finkelstein, Sara Ann Jackson, Jamie Michelle Bleicher, Eric Matthew Gayle Ellsworth, Dennis Morgan Smith, Jr.
  • Publication number: 20140296103
    Abstract: The application relates to a method of a predicting the presence of invasive pancreatic cancer or high grade dysplasia, pre-cancerous pancreatic states and non-neoplastic conditions comprising detailed molecular analysis incorporating DNA quality and quantity, K-ras mutational analysis and a broad spectrum of tumor suppressor gene linked microsatellite LOH. Methods of diagnosing, determining prognosis of and determining a course of treatment for pancreatic cancer or high grade dysplasia, pre-cancerous pancreatic states and non-neoplastic conditions are also provided.
    Type: Application
    Filed: June 16, 2014
    Publication date: October 2, 2014
    Inventors: Sydney David Finkelstein, Patricia Swalsky
  • Publication number: 20140154698
    Abstract: Disclosed herein are methods of accurately measuring carcinoembryonic antigen in a biological sample and methods of identifying and treating a mucinous cyst in a subject.
    Type: Application
    Filed: November 27, 2013
    Publication date: June 5, 2014
    Applicant: RedPath Integrated Pathology, Inc
    Inventors: Sydney David Finkelstein, Sara Ann Jackson, Jamie Michelle Bleicher, Eric Matthew Gayle Ellsworth, Dennis Morgan Smith, JR.
  • Publication number: 20130317317
    Abstract: Disclosed herein are methods for treating Barrett's metaplasia and esophageal adenocarcinoma and methods for determining mutational load as a predictor of the risk of disease progression from Barrett's metaplasia to esophageal adenocarcinoma.
    Type: Application
    Filed: July 30, 2013
    Publication date: November 28, 2013
    Inventors: Eric Matthew Gayle Ellsworth, Sydney David Finkelstein, Sara Ann Jackson, Brendan Corcoran, Dennis Morgan Smith, JR.
  • Patent number: 7014999
    Abstract: The present invention pertains to a method for topographic genotyping. The method comprises the steps of placing a biological specimen having DNA of a patient under a microscope. Then there is the step of inspecting the biological specimen microscopically with the microscope. Next there is the step of choosing a microscope size target on the biological specimen based on its histopathologic characteristics. Next there is the step of separating the target from the specimen. Then there is the step of obtaining DNA sequences from the target so the DNA sequences can be amplified. Next there is the step of amplifying the DNA sequences. Then there is the step of detecting mutations in the DNA sequences. The present invention pertains to a method for topographic genotyping. The method comprises the steps of separating a section from a specimen of fixative treated tissue. Then there is the step of obtaining DNA sequences from the section.
    Type: Grant
    Filed: November 5, 2001
    Date of Patent: March 21, 2006
    Assignee: RedPath Integrated Pathology, Inc.
    Inventors: Sydney David Finkelstein, Patricia Anne Finkelstein
  • Publication number: 20020076724
    Abstract: The present invention pertains to a method for topographic genotyping. The method comprises the steps of placing a biological specimen having DNA of a patient under a microscope. Then there is the step of inspecting the biological specimen microscopically with the microscope. Next there is the step of choosing a microscope size target on the biological specimen based on its histopathologic characteristics. Next there is the step of separating the target from the specimen. Then there is the step of obtaining DNA sequences from the target so the DNA sequences can be amplified. Next there is the step of amplifying the DNA sequences. Then there is the step of detecting mutations in the DNA sequences. The present invention pertains to a method for topographic genotyping. The method comprises the steps of separating a section from a specimen of fixative treated tissue. Then there is the step of obtaining DNA sequences from the section.
    Type: Application
    Filed: November 5, 2001
    Publication date: June 20, 2002
    Inventors: Sydney David Finkelstein, Patricia Anne Finkelstein
  • Patent number: 6340563
    Abstract: A method for topographic genotyping is described. The method comprises the steps of placing a biological specimen having DNA of a patient under a microscope. Then there is the step of inspecting the biological specimen microscopically with the microscope. Next there is the step of choosing a microscope size target on the biological specimen based on its histopathologic characteristics. Next there is the step of separating the target from the specimen. Then there is the step of obtaining DNA sequences from the target so the DNA sequences can be amplified. Next there is the step of amplifying the DNA sequences. Then there is the step of detecting mutations in the DNA sequences. More specifically, the method comprises the steps of separating a section from a specimen of fixative treated tissue. Then there is the step of obtaining DNA sequences from the section.
    Type: Grant
    Filed: June 24, 1996
    Date of Patent: January 22, 2002
    Inventors: Sydney David Finkelstein, Patricia Anne Finkelstein