Patents by Inventor Sydney O. Ugwu

Sydney O. Ugwu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS OF MAKING AND USING PHARMACEUTICAL FORMULATIONS OF ANTINEOPLASTIC AGENTS
    Publication number: 20190336495
    Abstract: In its several embodiments, this invention discloses a pharmaceutical formulation comprising at least one antineoplastic agent or a pharmaceutically acceptable salt thereof, and at least one dissolution enhancing agent sufficient to substantially dissolve said at least one antineoplastic agent in at least one aqueous diluent, wherein said dissolution enhancing agent is urea, L-histidine, L-threonine, L-asparagine, L-serine, L-glutamine or mixtures thereof; a lyophilized powder comprising said pharmaceutical formulation, and articles of manufacture thereof.
    Type: Application
    Filed: July 16, 2019
    Publication date: November 7, 2019
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Sydney O. Ugwu, Vinay Radhakrishnan, Peter M. Ihnat, Leonore C. Witchey-Lakshmanan
  • PROCESS OF MAKING AND USING PHARMACEUTICAL FORMULATIONS OF ANTINEOPLASTIC AGENTS
    Publication number: 20180078546
    Abstract: In its several embodiments, this invention discloses a pharmaceutical formulation comprising at least one antineoplastic agent or a pharmaceutically acceptable salt thereof, and at least one dissolution enhancing agent sufficient to substantially dissolve said at least one antineoplastic agent in at least one aqueous diluent, wherein said dissolution enhancing agent is urea, L-histidine, L-threonine, L-asparagine, L-serine, L-glutamine or mixtures thereof; a lyophilized powder comprising said pharmaceutical formulation, and articles of manufacture thereof.
    Type: Application
    Filed: November 29, 2017
    Publication date: March 22, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Sydney O. Ugwu, Vinay Radhakrishnan, Peter M. Ihnat, Leonore C. Witchey-Lakshmanan
  • PROCESS OF MAKING AND USING PHARMACEUTICAL FORMULATIONS OF ANTINEOPLASTIC AGENTS
    Publication number: 20160082005
    Abstract: In its several embodiments, this invention discloses a pharmaceutical formulation comprising at least one antineoplastic agent or a pharmaceutically acceptable salt thereof, and at least one dissolution enhancing agent sufficient to substantially dissolve said at least one antineoplastic agent in at least one aqueous diluent, wherein said dissolution enhancing agent is urea, L-histidine, L-threonine, L-asparagine, L-serine, L-glutamine or mixtures thereof; a lyophilized powder comprising said pharmaceutical formulation, and articles of manufacture thereof.
    Type: Application
    Filed: December 3, 2015
    Publication date: March 24, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Sydney O. Ugwu, Vinay Radhakrishnan, Peter M. Ihnat, Leonore C. Witchey-Lakshmanan
  • SYN3 COMPOSITIONS AND METHODS
    Publication number: 20150313926
    Abstract: Disclosed are aqueous and nonaqueous solution formulations containing agents that are useful for treating cancer.
    Type: Application
    Filed: July 13, 2015
    Publication date: November 5, 2015
    Inventors: Peter M. Ihnat, Leonore C. Witchey-Lakshmanan, Varda Sandweiss, Sydney O. Ugwu
  • SYN3 compositions and methods
    Patent number: 9115374
    Abstract: Disclosed are aqueous and lyophilized formulations containing SYN3 and methods of their use for treating bladder cancer.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: August 25, 2015
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: Peter M. Ihnat, Leonore C. Witchey-Lakshmanan, Varda Sandweiss, Sydney O. Ugwu
  • SYN3 compositions and methods
    Publication number: 20030170216
    Abstract: Disclosed are aqueous and nonaqueous solution formulations containing agents that are useful for treating cancer.
    Type: Application
    Filed: December 20, 2002
    Publication date: September 11, 2003
    Applicant: Schering-Plough Corporation
    Inventors: Peter M. Ihnat, Leonore C. Witchey-Lakshmanan, Varda Sandweiss, Sydney O. Ugwu