Patents by Inventor Syed Adnan Ali Shah

Syed Adnan Ali Shah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of producing tibolone metabolites by fermentation with
    Patent number: 8198041
    Abstract: A method of producing ?1,4-Tibolone (C21H26O2), 10?-Hydroxy-?4-tibolone (C21H28O3). 11?,15?-Dihydroxytibolone (C21H28O4) and 11?,15?-Dihydroxy-?5-tibolone (C21H28O4) by contacting tibolone and 3?,6?-Dihydroxytibolone (C21H32O3) by contacting 3?-hydroxytibolone with Cunninghamella elegans (ATCC 10028b) is reported.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: June 12, 2012
    Inventors: Attaur Rahman, Muhammed Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan
  • Method of producing tibolone metabolites by fermentation with
    Patent number: 8148558
    Abstract: Method of producing ?4-Tibolone by contacting tibolone with Fusarium lini (ATCC 9593) is reported.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: April 3, 2012
    Inventors: Attaur Rahman, Muhammed Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan
  • Method of producing tibolone metabolites by fermentation with
    Patent number: 8148557
    Abstract: Method of producing ?5-Tibolone (C21H28O2), 6?-Hydroxy-?4-tibolone (C21H28O3), 6?-Hydroxy-?4-tibolone (C21H28O3), 15?-Hydroxy-?4-tibolone (C21H28O3), 6?-Hydroxy-?1,4-tibolone (C21H28O3) and 6?-Methoxy-?4-tibolone (C22H30O3) contacting tibolone with Gibberella fujikuroi (ATCC 10704) is reported.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: April 3, 2012
    Inventors: Attaur Rahman, Muhammed Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan
  • Method of producing tibolone metabolites by fermentation with
    Patent number: 8148556
    Abstract: A new method of producing metabolites of tibolone comprising fermenting tibolone with Rhizopus stolonifer (ATCC 12938) resulting in the formation of ?4-Tibolone (C21H28O2), 6?-Hydroxytibolone, and 15?-Hydroxytibolone (C21H28O3) is reported.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: April 3, 2012
    Inventors: Attaur Rahman, Muhammed Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan
  • Method of producing tibolone metabolites by fermentation with Fusarium lini
    Publication number: 20110124042
    Abstract: Method of producing ?4-Tibolone by contacting tibolone with Fusarium lini (ATCC 9593) is reported.
    Type: Application
    Filed: January 27, 2011
    Publication date: May 26, 2011
    Applicant: INTERNATIONAL CENTER FOR CHEMICAL SCIENCES
    Inventors: Attaur Rahman, Mohammed Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan
  • Method of producing tibolone metabolites by fermentation with Cunninghamella elegans
    Publication number: 20110124044
    Abstract: A method of producing ?1,4-Tibolone (C21H26O2), 10?-Hydroxy-?4-tibolone (C21H28O3). 11?,15?-Dihydroxytibolone (C21H28O4) and 11?,15?-Dihydroxy-?5-tibolone (C21H28O4) by contacting tibolone and 3?,6?-Dihydroxytibolone (C21H32O3) by contacting 3?-hydroxytibolone with Cunninghamella elegans (ATCC 10028b) is reported.
    Type: Application
    Filed: January 27, 2011
    Publication date: May 26, 2011
    Applicant: INTERNATIONAL CENTER FOR CHEMICAL SCIENCES
    Inventors: Attaur Rahman, Mohammed Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan
  • Method of producing tibolone metabolites by fermentation with Gibberella fujikuroi
    Publication number: 20110124043
    Abstract: Method of producing ?5-Tibolone (C21H28O2), 6?-Hydroxy-?4-tibolone (C21H28O3), 6?-Hydroxy-?4-tibolone (C21H28O3), 15?-Hydroxy-?4-tibolone (C21H28O3), 6?-Hydroxy-?1,4-tibolone (C21H28O3) and 6?-Methoxy-?4-tibolone (C22H30O3) contacting tibolone with Gibberella fujikuroi (ATCC 10704) is reported.
    Type: Application
    Filed: January 27, 2011
    Publication date: May 26, 2011
    Applicant: INTERNATIONAL CENTER FOR CHEMICAL SCIENCES
    Inventors: Attaur Rahman, Mohammad Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan
  • Method of producing tibolone metabolites by fermentation with Rhizopus stolonifer
    Publication number: 20110124041
    Abstract: A new method of producing metabolites of tibolone comprising fermenting tibolone with Rhizopus stolonifer (ATCC 12938) resulting in the formation of ?4-Tibolone (C21H28O2), 6?-Hydroxytibolone, and 15?-Hydroxytibolone (C21H28O3) is reported.
    Type: Application
    Filed: January 27, 2011
    Publication date: May 26, 2011
    Applicant: INTERNATIONAL CENTER FOR CHEMICAL SCIENCES
    Inventors: Attaur Rahman, Mohammed Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan
  • Tyrosinase enzyme inhibitors from fungal hydroxylation of tibolone
    Publication number: 20090136434
    Abstract: Seven new and one known metabolites of tibolone were obtained by incubation of tibolone with various fungi. Their structures were elucidated by means of a homo and heteronuclear 2D NMR and by HREI-MS techniques. The relative stereochemistry was deduced by 2D NOESY experiment. These metabolites of tibolone were strong inhibitors of tyrosine enzyme and thus useful in producing skin lightning and preserving fruits and vegetables.
    Type: Application
    Filed: November 23, 2007
    Publication date: May 28, 2009
    Applicant: HEJ Research Institute
    Inventors: Attaur Rahman, Muhammad Iqbal Choudhary, Syed Adnan Ali Shah, Mahmud Tareq Hassan Khan
  • Alpha-glucosidase inhibitors from fungal hydroxylation of tibolone and hydroxytibolones
    Publication number: 20090137542
    Abstract: Sixteen new and one known metabolites were obtained by incubation of tibolone and hydroxytibolones with various fungi. Their structures were elucidated by means of a homo and heteronuclear 2D NMR and by HREI-MS techniques. The relative stereochemistry was deduced by 2D NOESY experiment. These metabolites have shown promising inhibitory activities against ?-glucosidase enzyme. Seven metabolites exhibited potent inhibitory activity against the ?-glucosidase enzyme and were thus found useful in the treatment of diabetes mellitus and other diseases related to the activity of ?-glucosidase enzyme.
    Type: Application
    Filed: November 23, 2007
    Publication date: May 28, 2009
    Applicant: International Center for Chemical Sciences
    Inventors: Attaur Rahman, Muhammed Iqbal Choudhary, Syed Adnan Ali Shah, Shamsun Nahar Khan