Patents by Inventor Syed K. Raza

Syed K. Raza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligonucleotide phosphate esters
    Patent number: 6015886
    Abstract: This invention relates to synthetic oligonucleotides that are useful for antisense based therapeutic applications. The synthetic oligonucleotides of this invention have modifications in the sugar phosphate backbone for improved antisense properties.
    Type: Grant
    Filed: February 5, 1997
    Date of Patent: January 18, 2000
    Assignees: ChemGenes Corporation, Oligos Etc., Inc.
    Inventors: Roderic M. K. Dale, Amy Arrow, Suresh C. Srivastava, Syed K. Raza
  • N-protected-2'-O-methyl-and N-protected-3'-O-methyl-ribonucleosides and their phosphoramidite derivatives
    Patent number: 5525719
    Abstract: This invention is directed to processes for producing high purity N-protected-2'-O-methyl-5'-dimethoxytrityl-3' ribonucleoside methoxy, N,N-diisopropyl phosphoramidites (group 1), and N-protected-2'-O-methyl-5'-dimethoxytrityl-3'-ribonucleoside ethoxy, N,N-diisopropyl phosphoramidites (group 2). This invention is further directed to the process for producing high purity 2'-O-methyl-5'-dimethoxytrityl-inosine (structure IX; group 3), and 2'-O-methyl-5'-dimethoxytrityl-inosine-3'-cyanoethyl, N,N-diisopropyl phosphoramidite (structure Xa; group 3). This invention is also directed to the process for producing high purity N-protected-3'-O-methyl-5'-dimethoxytrityl ribonucleosides (group 6), and N-protected-3'-O-methyl-5'-dimethoxytrityl-2'-ribonucleoside cyanoethyl, N,N-diisopropyl phosporamidites (group 7).
    Type: Grant
    Filed: May 24, 1993
    Date of Patent: June 11, 1996
    Assignee: Chemgenes Corporation
    Inventors: Saresh C. Srivastava, Syed K. Raza