Patents by Inventor Syed M. Noorwez

Syed M. Noorwez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized mutant opsin proteins
    Patent number: 9907762
    Abstract: Methods and compositions for stabilizing opsin protein, such as a Pro23His mutant opsin protein, in a vertebrate visual system, by administration of opsin-binding synthetic retinoids, are provided. The mutant opsin protein binds to the synthetic retinoid, which stabilizes the mutant opsin protein and/or ameliorates the effects of the mutant opsin protein on the vertebrate visual system.
    Type: Grant
    Filed: September 4, 2015
    Date of Patent: March 6, 2018
    Assignees: UNIVERSITY OF WASHINGTON, REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Krzysztof Palczewski, Shalesh Kaushal, Vladimir Kuksa, Syed M. Noorwez
  • STABILIZED MUTANT OPSIN PROTEINS
    Publication number: 20160045453
    Abstract: Methods and compositions for stabilizing opsin protein, such as a Pro23His mutant opsin protein, in a vertebrate visual system, by administration of opsin-binding synthetic retinoids, are provided. The mutant opsin protein binds to the synthetic retinoid, which stabilizes the mutant opsin protein and/or ameliorates the effects of the mutant opsin protein on the vertebrate visual system.
    Type: Application
    Filed: September 4, 2015
    Publication date: February 18, 2016
    Inventors: Krzysztof Palczewski, Shalesh Kaushal, Vladimir Kuksa, Syed M. Noorwez
  • Stabilized mutant opsin proteins
    Patent number: 9149446
    Abstract: Methods and compositions for stabilizing opsin protein, such as a Pro23His mutant opsin protein, in a vertebrate visual system, by administration of opsin-binding synthetic retinoids, are provided. The mutant opsin protein binds to the synthetic retinoid, which stabilizes the mutant opsin protein and/or ameliorates the effects of the mutant opsin protein on the vertebrate visual system.
    Type: Grant
    Filed: August 24, 2011
    Date of Patent: October 6, 2015
    Assignees: UNIVERSITY OF WASHINGTON, REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Krzysztof Palczewski, Shalesh Kaushal, Vladimir Kuksa, Syed M. Noorwez
  • STABILIZED MUTANT OPSIN PROTEINS
    Publication number: 20130072443
    Abstract: Methods and compositions for stabilizing opsin protein in a vertebrate visual system are provided by administration of opsin-binding synthetic retinoids.
    Type: Application
    Filed: September 14, 2012
    Publication date: March 21, 2013
    Applicants: Regents of the University of Minnesota, University of Washington
    Inventors: Krzysztof Palczewski, Shalesh Kaushal, Vladimir Kuksa, Syed M. Noorwez
  • STABILIZED MUTANT OPSIN PROTEINS
    Publication number: 20120041073
    Abstract: Methods and compositions for stabilizing opsin protein in a vertebrate visual system are provided by administration of opsin-binding synthetic retinoids.
    Type: Application
    Filed: August 24, 2011
    Publication date: February 16, 2012
    Applicants: REGENTS OF THE UNIVERSITY OF MINNESOTA, UNIVERSITY OF WASHINGTON
    Inventors: KRZYSZTOF PALCZEWSKI, SHALESH KAUSHAL, VLADIMIR KUKSA, SYED M. NOORWEZ
  • Compositions and Methods for Treating or Preventing Ophthalmic Light Toxicity
    Publication number: 20090291919
    Abstract: Methods are disclosed for treating ophthalmic conditions related to the production of toxic visual cycle products that accumulate in the eye, and are associated with reactions of the visual cycle during medical procedures that expose the eye to light, most commonly the various forms of ophthalmic surgery. Compounds and compositions useful in the these methods, either alone or in combination with other therapeutic agents, are also described, along with methods of screening for new agents useful in said treatments.
    Type: Application
    Filed: January 21, 2009
    Publication date: November 26, 2009
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Shalesh Kaushal, Syed M. Noorwez
  • Opsin Stabilizing Compounds and Methods of Use
    Publication number: 20090286808
    Abstract: The present invention provides compositions and methods useful in the treatment and/or prevention of ophthalmic conditions and diseases, such as retinitis pigmentosa, that are dependent upon or related to misfolded opsin proteins in vivo. In addition, screening assays for agents useful in such treatment methods are described.
    Type: Application
    Filed: January 21, 2009
    Publication date: November 19, 2009
    Applicant: University of Florida Research Foundation, Inc.
    Inventors: Shalesh Kaushal, Syed M. Noorwez, David A. Ostrov
  • Stabilized mutant opsin proteins
    Publication number: 20040242704
    Abstract: Methods and compositions for stabilizing opsin protein in a vertebrate visual system are provided by administration of opsin-binding synthetic retinoids.
    Type: Application
    Filed: March 15, 2004
    Publication date: December 2, 2004
    Applicants: University of Washington, TechTransfer - Invention Licensing, Regents of the University of Minnesota
    Inventors: Krzysztof Palczewski, Shalesh Kaushal, Vladimir Kuksa, Syed M. Noorwez