Patents by Inventor Syed R. Husain

Syed R. Husain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synergistic combination of IL-4, interferon gamma, and interferon alpha in treating ovarian cancer
    Patent number: 10849960
    Abstract: Methods and compositions are disclosed for treating a subject with a cancer. The compositions can include a chimeric molecule comprising an agent that specifically binds the interleukin 4 receptor (IL-4R) and a toxic moiety, an interferon alpha (IFN?), and an interferon gamma (IFN?). In some non-liming embodiments, the compositions can also include monocytes. The methods disclosed herein include administering a therapeutically effective amount of the compositions taught herein to a subject with cancer, thereby treating the cancer in the subject, wherein cells in the cancer express IL-4R. In some non-liming embodiments, the methods can also include administering monocytes.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: December 1, 2020
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Raj K. Puri, Kathryn C. Zoon, Syed R. Husain, Daniel S. Green
  • SYNERGISTIC COMBINATION OF IL4 RECEPTOR TARGETED AGENTS, INTERFERON GAMMA, AND INTERFERON ALPHA FOR USE IN TREATING OVARIAN CANCER
    Publication number: 20200282020
    Abstract: Methods and compositions are disclosed for treating a subject with a cancer. The compositions can include a chimeric molecule comprising an agent that specifically binds the interleukin 4 receptor (IL-4R) and a toxic moiety, an interferon alpha (IFN?), and an interferon gamma (IFN?). In some non-liming embodiments, the compositions can also include monocytes. The methods disclosed herein include administering a therapeutically effective amount of the compositions taught herein to a subject with cancer, thereby treating the cancer in the subject, wherein cells in the cancer express IL-4R. In some non-liming embodiments, the methods can also include administering monocytes.
    Type: Application
    Filed: September 7, 2018
    Publication date: September 10, 2020
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Servic
    Inventors: Raj K. Puri, Kathryn C. Zoon, Syed R. Husain, Daniel S. Green
  • Liposome encapsulated taxol and a method of using the same
    Patent number: 5424073
    Abstract: Liposomal-encapsulated taxol or an antineoplastic derivative thereof or a mixture thereof is provided which is used to effect a therapeutically enhanced method of treating cancer, and which may be used advantageously in combination with hyperthermia. The liposomes confer enhanced stability and solubility to taxol or derivatives thereof.
    Type: Grant
    Filed: October 14, 1993
    Date of Patent: June 13, 1995
    Assignee: Georgetown University
    Inventors: Aquilur Rahman, Rafael Rafaeloff, Syed R. Husain