Abstract: An orbital drilling device includes, on the same frame: a motor rotating a cutting tool on itself; a first, interior, eccentric, receiving the motor, mounted so as to be able to rotate; a second, exterior, eccentric, receiving the first eccentric, mounted so as to be able to rotate; a reference body, secured to the frame, receiving the second eccentric, mounted so as to be able to rotate; a first unit for driving the first eccentric; a second unit for driving the second eccentric, simultaneously with the rotation of the first eccentric; and a controller configured to reproduce any path of the cutting tool in the zone by continuous control of the angular offset between the first eccentric and the second eccentric.

Abstract: Disclosed is a drilling tool intended to cooperate with a tooling including at least one guide orifice, including: a hollow nose part, through which a drilling member is intended to pass; and a gripping clamp, slidingly mounted on the hollow nose part, the sliding of the gripping clamp rearward along the hollow nose part leading to its radial expansion towards the outside. The distal end of the gripping clamp includes a bead protruding radially towards the outside, configured to ensure the stopping in translation of the drilling tool with respect to the tooling, by bearing against a wall of the tooling surrounding the guide orifice, when the gripping clamp is expanded radially towards the outside.

Abstract: A method for pushing, with a force a tool at the end of an articulated arm against a surface with a normal, including the steps of: positioning the tool against the surface; applying an increasing force to the tool until reaching a value, corresponding to a fraction of the force, the value of the applied force being monitored; measuring the orientation of the tool with respect to the normal, after having reached the force value; and redirecting the tool so as to recover its initial orientation with respect to the normal. Iteration is carried out to proceed, by repetition of steps to, while progressively increasing the force at each iteration, and until reaching the force value, the increase increment between two successive steps being smaller than a determined value.

Abstract: An orbital drilling device includes, on the same frame: a motor rotating a cutting tool on itself; a first, interior, eccentric, receiving the motor, mounted so as to be able to rotate; a second, exterior, eccentric, receiving the first eccentric, mounted so as to be able to rotate; a reference body, secured to the frame, receiving the second eccentric, mounted so as to be able to rotate; a first unit for driving the first eccentric; a second unit for driving the second eccentric, simultaneously with the rotation of the first eccentric; and a controller configured to reproduce any path of the cutting tool in the zone by continuous control of the angular offset between the first eccentric and the second eccentric.

Abstract: Disclosed are methods of favouring epithelial wound healing in a subject. Wounds suitable for this method include wounds located on the skin or in a cornea The methods comprise contacting a wound with an activator of an AKT pathway and/or an inhibitor of the MAPK pathway such as CREB inhibitors. Preferred compounds include SC-79, C646, curcumin, platelet-derived growth factor, 4?chloro-3-hydroxy-2-naphthanilide and fumonisin B. A model for wound healing is also disclosed. The model can be used to identify test compounds that are AKT activators or inhibitors of MAPK pathway, which are suitable to favoring epithelial wound healing.

Abstract: A handheld machining device (1), particularly for drilling, having a mechanism includes: a first mounting (20), on which a tool holder (2), and a motor (3, 4) arranged to rotate the tool holder (2), are mounted; a second mounting (30); and an element (40) for translatably guiding, between the first mounting (20) and the second mounting (30), a linear actuator (5) enabling the first mounting (20) to be spaced apart from the second mounting (30), and the first mounting (20) to be brought toward the second mounting (30). The motor (3, 4) is electric, and the rotor (4) of the first motor (3, 4) is directly mounted onto the tool holder (2) and is rigidly connected thereto.

Abstract: Disclosed are methods of favouring epithelial wound healing in a subject. Wounds suitable for this method include wounds located on the skin or in a cornea The methods comprise contacting a wound with an activator of an AKT pathway and/or an inhibitor of the MAPK pathway such as CREB inhibitors. Preferred compounds include SC-79, C646, curcumin, platelet-derived growth factor, 4?chloro-3-hydroxy-2-naphthanilide and fumonisin B. A model for wound healing is also disclosed. The model can be used to identify test compounds that are AKT activators or inhibitors of MAPK pathway, which are suitable to favoring epithelial wound healing.

Abstract: A handheld machining device (1), particularly for drilling, having a mechanism includes: a first mounting (20), on which a tool holder (2), and a motor (3, 4) arranged to rotate the tool holder (2), are mounted; a second mounting (30); and an element (40) for translatably guiding, between the first mounting (20) and the second mounting (30), a linear actuator (5) enabling the first mounting (20) to be spaced apart from the second mounting (30), and the first mounting (20) to be brought toward the second mounting (30). The motor (3, 4) is electric, and the rotor (4) of the first motor (3, 4) is directly mounted onto the tool holder (2) and is rigidly connected thereto.

Abstract: A handheld machining device (1), particularly for drilling, having a mechanism includes: a first mounting (20), on which a tool holder (2), and a motor (3, 4) arranged to rotate the tool holder (2), are mounted; a second mounting (30); and an element (40) for translatably guiding, between the first mounting (20) and the second mounting (30), a linear actuator (5) enabling the first mounting (20) to be spaced apart from the second mounting (30), and the first mounting (20) to be brought toward the second mounting (30). The motor (3, 4) is electric, and the rotor (4) of the first motor (3, 4) is directly mounted onto the tool holder (2) and is rigidly connected thereto.

Abstract: A handheld machining device (1), particularly for boring, having a mechanism includes: a first mounting (20), on which a tool holder (2), and a motor (3, 4) arranged to rotate the tool holder (2), are mounted; a second mounting (30); and an element (40) for translatably guiding, between the first mounting (20) and the second mounting (30), a linear actuator (5) enabling the first mounting (20) to be spaced apart from the second mounting (30), and the first mounting (20) to be brought toward the second mounting (30). The motor (3, 4) is electric, and the rotor (4) of the first motor (3, 4) is directly mounted onto the tool holder (2) and is rigidly connected thereto.

Abstract: A device for dispensing single components, in particular rivets of different shapes and sizes, wherein the rivets are conveyed to a riveting station one by one in a given direction along a path; the rivets are moved along and within an elastic sheath (11) by a pressure source (P); the device also includes a device for storing the components and includes a holder (24) for feeding the components one by one to the elastic sheath (11); the device provides for the uniform and steady feeding of rivets to riveting machines such as are used in the aircraft industry.

Abstract: A sensor arm (1) is inserted into a hole (3). The arm is mounted on a pivot (5) perpendicular to the arm axis so that it may be urged into engagement with the wall of the hole, e.g. by an air cylinder (12). The pivot (5) is in turn rotated about an axis passing through the hole, preferably by means of a rotary body (10). A bearing piece (16) controlling the sensor arm may be moved towards or away from the hole and rigidly supports a light sensor (8) that receives a light beam (7) from the sensor arm. The geometry of the hole is determined on the basis of the position where the light beam impinges on the sensor and the position of the bearing piece relative to the hole.

Abstract: Two riveting-set assemblies (14) are each mounted on a carrier device (4, 5) which may be an effector mounted on a robot arm (A, B), on each side of the workpieces (2, 3) to be joined by riveting. Each carrier device is provided with driving means which comprise an electric motor (21), preferably a brushless motor, which drives the riveting-set assembly translationally, for example via ball screws (18, 19). Control means (25) are designed to actuate the two motors (21) in such a manner that the riveting sets (14) encounter the rivet (1) with a time delay and/or a kinetic energy difference which are chosen in order to form the rivet in the desired manner, avoiding, at the workpieces to be joined, undesirable movements or stresses.

Abstract: Detachable device for joining together objects having holes intended to come into alignment, comprising:a tubular member made of an elastically deformable material and capable of passing through the holes when it is in the expanded state and of widening in order to be locked in the holes,an expansion rod sliding inside the tubular member and having a widened head,a body fastened to the tubular member and having a bore which extends the bore of the tubular member, and a support surface substantially at right angles to said bore,a locking member which can be immobilized at any point on the rod,an elastic member capable of exerting a determined force tending to move the body away from the locking member.The tubular member, the body and the elastic member preferably form a single piece.