Patents by Inventor Sylvan Frank

Sylvan Frank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing solid dispersions
    Publication number: 20030104065
    Abstract: The present invention is directed to improved methods for producing solid dispersions, especially pharmaceutical dispersions. These methods involve the dissolution of one or more insoluble or relatively insoluble substances, preferably pharmaceutically active substances, and/or one or more water-soluble substances, preferably carriers, in supercritical fluids and the subsequent removal of solvent by rapid expansion. These methods offer a number of advantages over traditional preparation methods and form formulations with highly desirable dissolution properties, especially for pharmaceuticals.
    Type: Application
    Filed: October 1, 2002
    Publication date: June 5, 2003
    Inventors: Arne Brodin, Sylvan Frank, Chao Ye
  • Small particle formation
    Patent number: 5780062
    Abstract: The present invention is concerned with the formation of small particles of organic compounds by precipitating said organic compounds in an aqueous medium containing polymer/amphiphile complexes. The process is preferably used to prepare a readily soluble pharmaceutically active compound.
    Type: Grant
    Filed: November 27, 1995
    Date of Patent: July 14, 1998
    Assignee: The Ohio State University Research Foundation
    Inventors: Sylvan Frank, Jan-Erik Lofroth, Levon Bostanian