Patents by Inventor Sylvestor Klutchko

Sylvestor Klutchko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-substituted amino acids as intermediates in the preparation of acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
    Patent number: 4532342
    Abstract: N-substituted amino acids are described which when coupled with 1,2,3,4-tetrahydroisoquinolines result in substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids as anti-hypertensive agents. The novel intermediates are in turn prepared by reacting an amino acid such as alanine with 2-bromo-4-phenyl butanoic acid or an ester thereof.
    Type: Grant
    Filed: June 8, 1982
    Date of Patent: July 30, 1985
    Assignee: Warner-Lambert Company
    Inventors: Milton L. Hoefle, Sylvestor Klutchko