Patents by Inventor Sylvia G. Kachalsky

Sylvia G. Kachalsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STR50 and uses thereof
    Publication number: 20090029456
    Abstract: The present invention relates to use of a novel gene, STR50 and to STR50 modulators in diagnostic, therapeutic and screening aspects related to neurotoxic events. More particularly, the present invention concerns diagnosing and treating neurodegenerative diseases, and screening for species which can be useful in treating the same.
    Type: Application
    Filed: May 8, 2008
    Publication date: January 29, 2009
    Inventors: Sylvia G. Kachalsky, Alexander Faerman, Yehuda Per-Or
  • Methods of preventing or treating brain ischemia or brain injury
    Patent number: 7202211
    Abstract: The present invention relates to use of Narp inhibitor in order to promote or enhance recovery from ischemic events, particularly focal ischemia of the central nervous system, as well as for preventing or diminishing chronic degenerative changes.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: April 10, 2007
    Assignees: Astellas Pharma Inc., Quark Biotech, Inc.
    Inventors: Alexander Faerman, Sylvia G. Kachalsky, Gregory Hirsch Idelson
  • Genes involved in stroke response and/or regulated by FK506, proteins encoded thereby, and methods of use
    Patent number: 6833237
    Abstract: Genes and the proteins encoded thereby that are involved in stroke response and/or are regulated by FK506 are disclosed. These genes were discovered using in vivo or in vitro stroke models by determining which genes were differentially upregulated or downregulated upon treatment of the model with FK506. They were also found by a functional assay of genes specifically selected for conferring to cells resistance to hypoxia, dopamine or glutamate treatment. The disclosure includes such genes and proteins as well as analogs, salts and functional derivatives of such proteins, and DNA encoding such analogs, and methods of use. Methods for treating the effects of stroke, hypoxia and/or ischemia by regulating such genes or proteins are disclosed. Methods for screening for compounds capable of regulating the genes and proteins of the invention are also disclosed.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: December 21, 2004
    Assignees: Quark Biotech, Inc., Fujitsawa Pharmaceutical Co., Ltd.
    Inventors: Elena Feinstein, Igor Mett, Sylvia G. Kachalsky, Svetlana Gorodin
  • STR50 and uses thereof
    Publication number: 20040068098
    Abstract: The present invention relates to use of a novel gene, STR50 and to STR50 modulators in diagnostic, therapeutic and screening aspects related to neurotoxic events. More particularly, the present invention concerns diagnosing and treating neurodegenerative diseases, and screening for species which can be useful in treating the same.
    Type: Application
    Filed: July 1, 2003
    Publication date: April 8, 2004
    Inventors: Sylvia G. Kachalsky, Alexander Faerman, Yehuda Pel-Or
  • Methods of preventing or treating brain ischemia or brain injury
    Publication number: 20030219430
    Abstract: The present invention relates to use of Narp inhibitor in order to promote or enhance recovery from ischemic events, particularly focal ischemia of the central nervous system, as well as for preventing or diminishing chronic degenerative changes.
    Type: Application
    Filed: February 20, 2003
    Publication date: November 27, 2003
    Inventors: Alexander Faerman, Sylvia G. Kachalsky, Gregory Hirsch Idelson