Patents by Inventor Sylvia Hopper

Sylvia Hopper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel genes encoding novel proteolytic enzymes
    Publication number: 20090275079
    Abstract: The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Application
    Filed: October 25, 2007
    Publication date: November 5, 2009
    Applicant: DSM IP ASSETS B.V.
    Inventors: Luppo Edens, Alard Van Albertus Dijk, Phillip Krubasik, Kaj Albermann, Alexander Stock, Erik Kimpel, Sabrine Klaubauer, Christian Wagner, Andreas Fritz, Wilk Von Gustedt, Oliver Henrich, Dieter Maier, Fabio Spreafico, Ulrike Folkers, Sylvia Hopper, Wolfram Kemmner, Pamela Tan, Josephine Stiebler, Ricahrd Albang
  • Genes from encoding enzymes involved in vitamin Bbiosynthesis
    Patent number: 7527953
    Abstract: Four new genes, and the enzymes that they encode, are disclosed, which are present in Propionibacterium freudenreichii, and which are involved in at least five steps in the biosynthetic pathway of vitamin B12. The four enzymes are: A: cobyrinic acid a, c-diamide synthase; B: a bifunctional enzyme, which is a cobinamide kinase and a cobinamide phosphate guanyl transferase; C: a cobalamin 5-phosphate synthase; and D: an adenosyl transferase. Genes encoding the four enzymes can be placed in Propionibacteria shuttle vectors and used to transform Propionibacteria hosts, in order to improve the production of vitamin B12 or a precursor thereof on an industrial scale during fermentation.
    Type: Grant
    Filed: July 25, 2003
    Date of Patent: May 5, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Herman Jan Pel, Sylvia Hopper
  • Genes encoding novel proteolytic enzymes
    Patent number: 7323327
    Abstract: The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: January 29, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Luppo Edens, Albertus Van Dijk, Philipp Krubasik, Kaj Albermann, Alexander Stock, Erik Kimpel, Sabine Klugbauer, Christian Wagner, Andreas Fritz, Wilk Von Gustedt, Oliver Heinrich, Dieter Maier, Fabio Spreafico, Ulrike Folkers, Sylvia Hopper, Wolfram Kemmner, Pamela Tan, Josephine Stiebler, Richard Albang
  • Genes from propionibacterium freudenreichii encoding enzymes involved in vitamin b12 biosynthesis
    Publication number: 20060183188
    Abstract: Four new genes, and the enzymes that they encode, are disclosed, which are present in Propionibacterium freudenreichii, and which are involved in at least five steps in the biosynthetic pathway of vitamin B12. The four enzymes are: A: cobyrinic acid a, c-diamide synthase; B: a bifunctional enzyme, which is a cobinamide kinase and a cobinamide phosphate guanyl transferase; C: a cobalamin 5-phosphate synthase; and D: an adenosyl transferase. Genes encoding the four enzymes can be placed in Propionibacteria shuttle vectors and used to transform Propionibacteria hosts, in order to improve the production of vitamin B12 or a precursor thereof on an industrial scale during fermentation.
    Type: Application
    Filed: July 25, 2003
    Publication date: August 17, 2006
    Inventors: Herman Pel, Sylvia Hopper
  • Novel Genes Encoding Novel Proteolytic Enzymes
    Publication number: 20050064403
    Abstract: The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Application
    Filed: February 22, 2002
    Publication date: March 24, 2005
    Inventors: Luppo Edens, Dijk Alard, Philipp Krubasik, Kaj Albermann, Stock Alexander, Erik Kimpel, Sabine Klugbauer, Christian Wagner, Andreas Fritz, Gustedt Wilk, Oliver Heinrich, Dieter Maier, Fabio Spreafico, Ulrike Folkers, Sylvia Hopper, Wolfram Kemmner, Pamela Tan, Josephine Stiebler, Richard Albang