Abstract: Treatment methods for inhibiting tumor growth and angiogenesis are described. The methods involve treatment with an inhibitor of delta protein kinase C (?PKC) or an inhibitor of beta-II protein kinase C (?IIPKC), in an amount effective to decrease the rate of growth of a solid tumor and/or to inhibit tumor angiogenesis.

Abstract: This invention relates to a method for separating long-term label retaining cells or stem cells. In particular, this invention relates to a method for separating long-term label retaining cells and/or stem cells from tissues or individuals and for measuring proliferation rates of long-term label retaining cells and stem cells, as well as determining clonal expansion (proliferative history) of cell lineages from the tissues of the individual. The cells may be double-labeled with a cell-lineage marking label and isotopically labeled DNA synthesis precursor prior to physical separation.