Patents by Inventor Sylvia Koivunen

Sylvia Koivunen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticle suitable for delivery of a biomolecule into or out of a membrane enclosed cell or cell organelle
    Patent number: 8557289
    Abstract: A nano sized particle for in vitro or ex vivo biomolecule delivery to cell cultures through heat induced endosomal release comprising a superparamagnetic core coated in a heat sensitive coating, comprising membrane disruptive components and binding sites for attachment of biomolecules and markers to be delivered is provided. A method is provided for introducing the release effect of a plurality of said biomolecule and endosomal disrupture molecules by applying an alternating field to a cell culture harboring the particle described by the invention.
    Type: Grant
    Filed: August 21, 2006
    Date of Patent: October 15, 2013
    Assignee: Genovis AB
    Inventors: Sarah Fredriksson, Sylvia Koivunen, Fredrik Olsson, Hanna-Karin Toftevall
  • Nanoparticle suitable for delivery of a biomolecule into or out of a membrane enclosed cell or cell organelle
    Publication number: 20090304796
    Abstract: A nano sized particle for in vitro or ex vivo biomolecule delivery to cell cultures through heat induced endosomal release comprising a superparamagnetic core coated in a heat sensitive coating, comprising membrane disruptive components and binding sites for attachment of biomolecules and markers to be delivered is provided. A method is provided for introducing the release effect of a plurality of said biomolecule and endosomal disrupture molecules by applying an alternating field to a cell culture harbouring the particle described by the invention.
    Type: Application
    Filed: August 21, 2006
    Publication date: December 10, 2009
    Inventors: Sarah Fredriksson, Sylvia Koivunen, Hanna-Karin Toftevall