Patents by Inventor Sylvia Sanquer

Sylvia Sanquer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for detecting or quantifying CTP and CTP synthase activity
    Patent number: 10731197
    Abstract: The present invention relates to a method for detecting or quantifying CTP in a cell sample comprising at least two nucleotide triphosphates by cationic ion pairing chromatography coupled to mass spectrometry, to a method for detecting or quantifying CTP synthase activity based on the method for detecting or quantifying CTP, and to their use in methods for screening potential immunosuppressive or anti-cancer compounds and in methods for determining the appropriate dose of an immunosuppressive or anti-cancer compound inhibiting CTP synthase activity for a treated subject.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: August 4, 2020
    Assignees: Assitance Publique-Hopitaux de Paris, Imagine Institut Des Maladies Genetiques Necker Enfants Malades, Universite Paris Descartes, Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS)
    Inventors: Sylvia Sanquer, Anne-Claire Boschat, Sylvain Latour, Emmanuel Martin, Robert Barouki
  • Methods For Detecting Or Quantifying CTP And CTP Synthase Activity
    Publication number: 20180298420
    Abstract: The present invention relates to a method for detecting or quantifying CTP in a cell sample comprising at least two nucleotide triphosphates by cationic ion pairing chromatography coupled to mass spectrometry, to a method for detecting or quantifying CTP synthase activity based on the method for detecting or quantifying CTP, and to their use in methods for screening potential immunosuppressive or anti-cancer compounds and in methods for determining the appropriate dose of an immunosuppressive or anti-cancer compound inhibiting CTP synthase activity for a treated subject.
    Type: Application
    Filed: October 10, 2016
    Publication date: October 18, 2018
    Applicants: Assistance Publique-Hopitaux de Paris, Imagine Institut Des Maladies Genetiques Necker Enfants Malades, Universite Paris Descartes, Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (CNRS)
    Inventors: Sylvia Sanquer, Anne-Claire Boschat, Sylvain Latour, Emmanuel Martin, Robert Barouki
  • Method for measuring calcineurin activity
    Patent number: 9290792
    Abstract: The present invention relates to a method for measuring the activity of calcineurin in a biological sample wherein a kinase inhibitor is present in the assay reaction mix.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: March 22, 2016
    Assignees: UNIVERSITE PARIS DESCARTES, ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
    Inventors: Sylvia Sanquer, Robert Barouki, Laurence Herry
  • METHOD FOR MEASURING CALCINEURIN ACTIVITY
    Publication number: 20150050681
    Abstract: The present invention relates to a method for measuring the activity of calcineurin in a biological sample wherein a kinase inhibitor is present in the assay reaction mix.
    Type: Application
    Filed: February 14, 2013
    Publication date: February 19, 2015
    Applicant: UNIVERSITE PARIS DESCARTES
    Inventors: Sylvia Sanquer, Robert Barouki, Laurence Herry