Patents by Inventor Sylvia Unger

Sylvia Unger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Liver disease-related methods and systems
    Patent number: 7668661
    Abstract: The invention provides diagnostic methods, kits, and systems, and related computer-readable media, which use multiple blood marker values, including serum and plasma marker values, to aid in the diagnosis of the status or progress of a liver disease in a patient. The invention also provides methods and systems, and related computer-readable media, that use blood marker values, including serum and plasma marker values: (1) to screen for active ingredients useful in the treatment of a liver disease; (2) to aid in the selection of treatment regimens for patients that are predisposed to, or suffer from, liver disease; and (3) to aid in the design of clinical programs useful in monitoring the status or progress of liver disease in one or more patients.
    Type: Grant
    Filed: June 15, 2004
    Date of Patent: February 23, 2010
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Michael Volker, Michael Becka, Werner Kroll, Andreas Knorr, Sylvia Unger, Mathias Gehrmann, Guido Hennig, Elmar-Reinhold Burchardt, Michael J. Arthur, Alastair D. Burt, Massimo Pinzani, Detlef Schuppan, Robert P. Thiel, Christoph Petry, William Rosenberg
  • Liver disease-related methods and systems
    Publication number: 20070172907
    Abstract: The invention provides diagnostic methods, kits, and systems, and related computer-readable media, which use multiple blood marker values, including serum and plasma marker values, to aid in the diagnosis of the status or progress of a liver disease in a patient. The invention also provides methods and systems, and related computer-readable media, that use blood marker values, including serum and plasma marker values: (1) to screen for active ingredients useful in the treatment of a liver disease; (2) to aid in the selection of treatment regimens for patients that are predisposed to, or suffer from, liver disease; and (3) to aid in the design of clinical programs useful in monitoring the status or progress of liver disease in one or more patients.
    Type: Application
    Filed: June 15, 2004
    Publication date: July 26, 2007
    Inventors: Michael Volker, Michael Becka, Werner Kroll, Andreas Knorr, Sylvia Unger, Mathias Gehrmann, Guido Hennig, Elmar-Reinhold Burchardt, Michael Arthur, Alastair Burt, Massimo Pinzani, Detlef Schuppan, Robert Thiel, Christoph Petry, William Rosenberg
  • Assessment of liver fibrosis scoring with serum marker algorithms
    Patent number: 7141380
    Abstract: The present invention concerns a method for diagnosing liver fibrosis wherein two or more diagnostic markers are measured and the measurements are correlated by a mathematic algorithm characterized in that the diagnostic markers are selected from the group N-terminal procollagen III propeptide (PIIINP), Collagen IV, Collagen VI, Tenascin, Laminin, Hyaluronan, MMP-2, TIMP-1 and MMP-9/TIMP-1 complex. The algorithm can be used to predict the histological score of a liver biopsy.
    Type: Grant
    Filed: April 26, 2001
    Date of Patent: November 28, 2006
    Inventors: Michael Volker, Michael Becka, Werner Kroll, Andreas Knorr, Mathias Gehrmann, Guido Hennig, Sylvia Unger, Elmar-Reinhold Burchardt, Michael J. Arthur, Alastair D. Burt, Massimo Pinzani, Detlef Schuppan
  • Assessment of liver fibrosis scoring with serum marker algorithms
    Publication number: 20040053242
    Abstract: The present invention concerns a method for diagnosing liver fibrosis wherein two or more diagnostic markers are measured and the measurements are correlated by a mathematic algorithm characterized in that the diagnostic markers are selected from the group N-terminal procollagen III propeptide (PIIINP), Collagen IV/, Collagen VI, Tenascin, Laminin, Hyaluronan, MMP-2, TIMP-1 and MMP-9/TIMP complex. The algorithm can be used to predict the histological score of a liver biopsy.
    Type: Application
    Filed: October 7, 2003
    Publication date: March 18, 2004
    Inventors: Michael Volker, Michael Becka, Werner Kroll, Andreas Knorr, Mathias Gehrmann, Guido Hennig, Sylvia Unger, Elmar-Reinhold Burchardt, Michael J. Arthur, Alastair D. Burt, Massimo Pinzani, Detlef Schuppan
  • Method for specifically detecting tumor cells and their precursors in uterine cervical smears by simultaneously measuring at least 2 different molecular markers
    Publication number: 20020106685
    Abstract: The present invention relates to an automatable method for obtaining an improved diagnosis of cancer, and its precancerous stages in uterine cervical smears by simultaneously staining and detecting at least two different molecular markers, which exhibit a disease-associated change in gene expression, in a cell by means of using antibodies or nucleic acid probes.
    Type: Application
    Filed: December 17, 2001
    Publication date: August 8, 2002
    Inventors: Guido Henning, Ralph Wirtz, Margit Doth, Kerstin Bohmann, Sylvia Unger