Patents by Inventor Sylvia van Drunen Littel-van den Hurk

Sylvia van Drunen Littel-van den Hurk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination adjuvant formulation
    Patent number: 9061001
    Abstract: Methods and compositions for enhancing an immune response to a selected antigen are described. The methods are useful for the treatment and prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites. The methods and compositions include host defense peptides, polyphosphazenes and immunostimulatory sequences to enhance the immune response to a coadministered antigen.
    Type: Grant
    Filed: October 15, 2009
    Date of Patent: June 23, 2015
    Assignees: University of Saskatchewan, Dalhousie University, International Vaccines Institute, University of British Columbia
    Inventors: Sylvia van Drunen Littel-van den Hurk, Volker Gerdts, Andrew Potter, Lorne Babiuk, Robert Hancock, Scott Halperin, Jennifer Kovacs-Nolan, George Mutwiri, Song Lee, Mi-Na Kweon, Jason Kindrachuk, Melissa Elliott
  • Combination adjuvant formulation
    Publication number: 20100239611
    Abstract: Methods and compositions for enhancing an immune response to a selected antigen are described. The methods are useful for the treatment and prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites. The methods and compositions include host defense peptides, polyphosphazenes and immunostimulatory sequences to enhance the immune response to a coadministered antigen.
    Type: Application
    Filed: October 15, 2009
    Publication date: September 23, 2010
    Inventors: Sylvia van Drunen Littel-van den Hurk, Volker Gerdts, Andrew Potter, Lorne Babiuk, Robert Hancock, Scott Halperin, Jennifer Kovacs-Nolan, George Mutwiri, Song Lee, Mi-Na Kweon, Jason Kindrachuk, Melissa Elliot
  • In utero oral nucleic acid immunization
    Patent number: 6946448
    Abstract: Methods of nucleic acid immunization comprising the in utero delivery of nucleic acid molecules that encode one or more selected antigens to a vertebrate fetus are disclosed.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: September 20, 2005
    Assignee: University of Saskatchewan
    Inventors: Volker Gerdts, Lorne Babiuk, Sylvia van Drunen Littel-van den Hurk, Philip J. Griebel
  • In utero oral nucleic acid immunization
    Publication number: 20030086905
    Abstract: Methods of nucleic acid immunization comprising the in utero delivery of nucleic acid molecules that encode one or more selected antigens to a vertebrate fetus are disclosed.
    Type: Application
    Filed: May 23, 2002
    Publication date: May 8, 2003
    Inventors: Volker Gerdts, Lorne Babiuk, Sylvia van Drunen Littel-van den Hurk, Philip J. Griebel
  • In utero oral nucleic acid immunization
    Publication number: 20020110567
    Abstract: Methods of nucleic acid immunization comprising the in utero delivery of nucleic acid molecules that encode one or more selected antigens to a vertebrate fetus are disclosed.
    Type: Application
    Filed: August 10, 2001
    Publication date: August 15, 2002
    Inventors: Volker Gerdts, Lorne Babiuk, Sylvia van Drunen Littel-van den Hurk, Philip J. Griebel
  • Adjuvant formulation with enhanced immunogenic activity, and related compositions and methods
    Patent number: 5951988
    Abstract: Adjuvant formulations are provided containing quaternary ammonium salts in conjunction with an oil component which may be a mineral oil, an animal oil, a vegetable oil, a mixture thereof, or an oil-in-water emulsion of one or more of such oils. These formulations are useful in conjunction with known immunological substances, e.g., viral or bacterial antigens in a vaccine composition, in order to enhance the immunogenic response. The compositions are also useful without an incorporated antigen as nonspecific immunostimulatory formulations.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 14, 1999
    Assignee: University of Saskatchewan
    Inventors: Sylvia van Drunen Littel-van den Hurk, Timothy Zamb, Mark J. Redmond