Patents by Inventor Sylviane Giorgi-Renault

Sylviane Giorgi-Renault has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Water soluble 4-azapodophyllotoxin analogs
    Patent number: 9783547
    Abstract: The present invention relates to 4-azapodophyllotoxin analogs of formula (I) in which X, R1, R2, R3, R4 and Ar are as defined in claim 1, preferably a pharmaceutically acceptable salt thereof, optionally in the form of a solvate, a composition comprising said analogs, their use as medicament, in particular for the treatment of cancer, and a process for their preparation.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: October 10, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS DESCARTES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), ECOLE NATIONALE SUPERIEURE DE CHIMIE DE PARIS
    Inventors: Guy Chabot, Sylviane Giorgi-Renault, Stéphanie Desbene-Finck, Philippe Helissey, Raphaël Labruere, Marlène Testud, Daniel Scherman
  • WATER SOLUBLE 4-AZAPODOPHYLLOTOXIN ANALOGS
    Publication number: 20160333022
    Abstract: The present invention relates to 4-azapodophyllotoxin analogs of formula (I) in which X, R1, R2, R3, R4 and Ar are as defined in claim 1, preferably a pharmaceutically acceptable salt thereof, optionally in the form of a solvate, a composition comprising said analogs, their use as medicament, in particular for the treatment of cancer, and a process for their preparation.
    Type: Application
    Filed: January 15, 2015
    Publication date: November 17, 2016
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS DESCARTES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M EDICALE (INSERM), ECOLE NATIONALE SUPERIEURE DE CHIMIE DE PARIS
    Inventors: Guy CHABOT, Sylviane GIORGI-RENAULT, Stéphanie DESBENE-FINCK, Philippe HELISSEY, Raphaël LABRUERE, Marléne TESTUD, Daniel SCHERMAN
  • Tricyclic dihydroquinoline derivatives,method for preparing same and pharmaceutical compositions containing same
    Publication number: 20040198981
    Abstract: Compound of formula (I): 1
    Type: Application
    Filed: November 10, 2003
    Publication date: October 7, 2004
    Inventors: Henri-Philippe Husson, Sylviane Giorgi-Renault, Stephanie Desbene, John Hickman, Alain Pierre, Laurence Kraus-Berthier, Bruno Pfeiffer, Pierre Renard
  • Dihydrofuro[3,4-b]quinolin-1-one compounds
    Patent number: 6548515
    Abstract: The invention relates to compound of formula (I): wherein: represents a single or double bond, R0 represents hydrogen or hydroxy or alkoxy, R1 and R2, which are identical or different, each represents hydrogen or halogen or alkyl, alkoxy, hydroxy, polyhaloalkyl, nitro or optionally substituted amino or  wherein m represents an integer such that 1≦m≦4, or form together with the carbon atoms carrying them an aromatic or non-aromatic, mono- or bi-cyclic group having from 5 to 12 ring members and optionally containing 1 or 2 hetero atoms selected from O, S and N, R3 represents hydrogen or aryl, heteroaryl, cycloalkyl, optionally substituted alkyl or a group of formula COR7 wherein R7 represents aryl, optionally substituted alkyl, optionally substituted amino or OR10 wherein R10 represents aryl or optionally substituted alkyl, X represents oxygen or sulphur or —CH2— or —CH2—CH2—, Ar represents aryl, heteroaryl or arylalkyl, its op
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: April 15, 2003
    Assignee: Les Laboratories Servier
    Inventors: Henri-Philippe Husson, Sylviane Giorgi-Renault, Christophe Tratrat, Ghanem Atassi, Alain Pierre, Pierre Renard, Bruno Pfeiffer