Patents by Inventor Sylvie Claudette Alonso

Sylvie Claudette Alonso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Influenza vaccine, composition, and methods of use
    Publication number: 20230364217
    Abstract: The invention relates to compositions and vaccines that include a mutated Bordetella strain for treating or preventing an influenza infection in a mammal. In addition, the invention further provides methods for protecting a mammal against infection by influenza and/or eliciting an immune response against an influenza virus in a mammal using the composition or vaccine.
    Type: Application
    Filed: April 19, 2023
    Publication date: November 16, 2023
    Inventors: Sylvie Claudette Alonso, Rui Li, Vincent TK Chow, Camille Locht
  • Prevention of pertussis using adenylate cyclase deficient Bordetella strains
    Patent number: 10369207
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: August 6, 2019
    Assignees: National University of Singapore, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur de Lille
    Inventors: Sylvie Claudette Alonso, Annabelle Rui Fen Lim, Camille Locht
  • Prevention of Pertussis Using Adenylate Cyclase Deficient Bordetella Strains
    Publication number: 20180339035
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Application
    Filed: July 12, 2018
    Publication date: November 29, 2018
    Inventors: Sylvie Claudette Alonso, Rui Fen, Annabelle Lim, Camille Locht
  • Prevention of using adenylate cyclase deficient strains
    Patent number: 10046044
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: August 14, 2018
    Assignees: National University of Singapore, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur de Lille
    Inventors: Sylvie Claudette Alonso, Rui Fen Annabelle Lim, Camille Locht
  • Prevention of Pertussis Using Adenylate Cyclase Deficient Bordetella Strains
    Publication number: 20170202944
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Application
    Filed: April 3, 2017
    Publication date: July 20, 2017
    Inventors: Sylvie Claudette Alonso, Rui Fen, Annabelle Lim, Camille Locht
  • Adenylate cyclase deficient bordetella strains
    Patent number: 9655959
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: May 23, 2017
    Assignees: National University of Singapore, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur de Lille
    Inventors: Sylvie Claudette Alonso, Rui Fen Annabelle Lim, Camille Locht
  • Influenza Vaccine, Composition, and Methods of Use
    Publication number: 20170106074
    Abstract: The invention relates to compositions and vaccines that include a mutated Bordetella strain for treating or preventing an influenza infection in a mammal. In addition, the invention further provides methods for protecting a mammal against infection by influenza and/or eliciting an immune response against an influenza virus in a mammal using the composition or vaccine.
    Type: Application
    Filed: November 17, 2016
    Publication date: April 20, 2017
    Inventors: Sylvie Claudette Alonso, Rui Li, Vincent TK Chow, Camille Locht
  • Effect of an attenuated strain against allergic disease
    Patent number: 9415077
    Abstract: Described herein are compositions, vaccines, and methods that include use of a mutated Bordetella strain against allergic diseases such as asthma and skin inflammation. Also described are kits. Other compositions, vaccines, and methods are also described.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: August 16, 2016
    Assignees: Institut National de la Sante et de la Recherche Medicale, Institut Pasteur de Lille, National University of Singapore
    Inventors: Sylvie Claudette Alonso, Rui Li, Camille Locht
  • Adenylate Cyclase Deficient Bordetella Strains
    Publication number: 20160095914
    Abstract: A CyaA-deficient B. pertussis mutant was constructed and used in a vaccine. The pertussis-specific antibody profile and Th17 response induced by vaccination with the mutant was surprisingly comparable to that induced by B. pertussis strains not deficient in CyaA.
    Type: Application
    Filed: September 30, 2015
    Publication date: April 7, 2016
    Inventors: Sylvie Claudette Alonso, Rui Fen, Annabelle Lim, Camille Locht
  • EFFECT OF AN ATTENUATED BORDETELLA STRAIN AGAINST ALLERGIC DISEASE
    Publication number: 20140271563
    Abstract: Described herein are compositions, vaccines, and methods that include use of a mutated Bordetella strain against allergic diseases such as asthma and skin inflammation. Also described are kits. Other compositions, vaccines, and methods are also described.
    Type: Application
    Filed: November 2, 2012
    Publication date: September 18, 2014
    Applicants: NATIONAL UNIVERSITY OF SINGAPORE, INSTITUT PASTEUR DE LILLE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Sylvie Claudette Alonso, Rui Li, Camille Locht