Patents by Inventor Sylvie CORNET

Sylvie CORNET has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF PAIN & INFLAMMATORY DISORDERS
    Publication number: 20250195626
    Abstract: The present invention is directed to a polypeptide for use in treating pain or an inflammatory disorder, wherein the polypeptide comprises a clostridial neurotoxin light-chain (L-chain), a clostridial neurotoxin translocation domain (HN domain) and/or a clostridial neurotoxin receptor binding domain (HC domain), wherein when the polypeptide comprises a clostridial neurotoxin L-chain, the L-chain is catalytically inactive. Also provided are corresponding methods of treatment and uses.
    Type: Application
    Filed: March 30, 2022
    Publication date: June 19, 2025
    Inventors: Mikhail KALINICHEV, Cindy PERIER, Christine FAVRE, Sylvie CORNET, Johannes KRUPP, Mark ELLIOTT, Jacqueline Caroline MAIGNEL, Hodan Ahmed IBRAHIM
  • CATALYTICALLY INACTIVE CLOSTRIDIAL NEUROTOXINS FOR THE TREATMENT OF PAIN & INFLAMMATORY DISORDERS
    Publication number: 20250066755
    Abstract: The present invention is directed to a polypeptide for use in treating pain or an inflammatory disorder, wherein the polypeptide comprises a clostridial neurotoxin light-chain (L-chain), a clostridial neurotoxin translocation domain (HN domain) and/or a clostridial neurotoxin receptor binding domain (Hc domain), wherein when the polypeptide comprises a clostridial neurotoxin L-chain, the L-chain is catalytically inactive. Also provided are corresponding methods of treatment and uses.
    Type: Application
    Filed: March 30, 2021
    Publication date: February 27, 2025
    Inventors: Mikhail KALINICHEV, Cindy PERIER, Christine FAVRE, Sylvie CORNET, Johannes KRUPP, Mark ELLIOTT
  • TREATMENT OF POST-OPERATIVE SURGICAL PAIN
    Publication number: 20230218728
    Abstract: The present invention relates to a clostridial neurotoxin for use in treating post-operative surgical pain in a patient, said method comprising administering to a patient a clostridial neurotoxin more than 5 days prior to surgery and wherein the clostridial neurotoxin is administered: i) intradermally; or ii) intrathecally. Also provided are corresponding methods of treatment and administration dosages of a clostridial neurotoxin.
    Type: Application
    Filed: July 16, 2021
    Publication date: July 13, 2023
    Inventors: Steve EVANS, Mikhail KALINICHEV, Laurent PONS, Sylvie CORNET, Stephane LEZMI