Abstract: An assembly for transmitting airborne acoustic waves, configured to be combined with a musical wind instrument having side holes, which instrument comprises a tubular body defining an air column and extending locally substantially along a first axis, the transmission assembly comprising: a device for emission of airborne acoustic waves in the air column, comprising an actuator which is separate from the tubular body and able to transform an electrical signal into airborne acoustic waves; a device for reception of airborne acoustic waves, comprising: a microphone suitable for receiving, after their propagation in the air column, the waves transformed by the actuator, the microphone being positioned off-centre with respect to the first axis; a transformation device suitable for transforming the waves received by the microphone into an electrical signal that is characteristic of a configuration of blocking of the side holes of the instrument.

Abstract: The present disclosure relates to peptide compounds and conjugate compounds, processes, methods and uses thereof for treating inflammation. For example, the compounds can comprise compounds; IKLSGGVQAKAGVINMDKSESM, formula (V) as set forth in SEQ ID NO: 5, GVRAKAGVRN(Nle)FKSESY, formula (X) as set forth in SEQ ID NO: 10 and YKSLRRK.APRWDAPLRDPALRQLL, formula (XI) as set forth in SEQ ID NO: 11 wherein at least one protecting group and/or at least one labelling agent is connected to said peptide compound at an N- and/or C-terminal end, for use in inhibiting or decreasing TNF-alpha-induced COX-2 expression in cells expression sortilin.

Abstract: A locating device equipping a mobile body, comprises an inertial platform, a 3D gyrometer and accelerometer, a calculation unit receiving measurements of the gyrometer and accelerometer a sampling frequency, and means to locate the mobile body, the calculation unit performing: a preliminary step where the mobile body travels a known trajectory, calculation of a coefficient of proportionality between distance actually traveled and raw distance obtained by integrating the time derivative of the acceleration along the trajectory; a following step of free displacement, location of the mobile body by dead-reckoning navigation procedure, being performed by using distance traveled the raw distance corrected by the proportionality coefficient.

Abstract: The present invention relates to a device for assisting in the navigation of a person, both inside and outside a building. The device, being fitted to the person, comprises at least: a computer (41) comprising in memory a digitized map of the place (1) in which the path of the person is planned between a departure point and an arrival point, and a location software; a human-machine interface linked to the computer; a set of sensors (42) worn by the person and linked to the computer, the sensors delivering information about the movements of the person; the location software performing a processing of the signals originating from the sensors (42) and from the interface, and performing the fusion of the data provided by the digitized map and the information arising from the sensors and from the interface, and then calculating on the basis of these data the absolute location of the person on the map and correcting the position estimation errors.

Abstract: An inertial navigation device for fitting to an article that bears intermittently against a surface. The device comprises an inertial unit having at least one inertial sensor, and a mechanical connector structure for connecting the inertial unit to the article. In the device, the connector structure is arranged (1) to provide mechanical coupling between the inertial unit and the article when the article is not bearing against the surface and (2) to provide mechanical decoupling therebetween when the article is bearing against the surface, in such a manner that the inertial unit is substantially stationary relative to the surface when the article is bearing against the surface. A shoe and equipment is provided with such a device.

Abstract: An inertial navigation device for fitting to an article that bears intermittently against a surface, the device comprising an inertial unit having at least one inertial sensor, and mechanical connection means connecting the inertial unit to the article, wherein the connection means are arranged to provide mechanical coupling between the inertial unit and the article when the article is not bearing against the surface and to provide mechanical decoupling therebetween when the article is bearing against the surface, in such a manner that the inertial unit is substantially stationary relative to the surface when the article is bearing against the surface. A shoe and equipment provided with such a device.

Abstract: The present invention relates to a device for assisting in the navigation of a person, both inside and outside a building. The device, being fitted to the person, comprises at least: a computer (41) comprising in memory a digitized map of the place (1) in which the path of the person is planned between a departure point and an arrival point, and a location software; a human-machine interface linked to the computer; a set of sensors (42) worn by the person and linked to the computer, the sensors delivering information about the movements of the person; the location software performing a processing of the signals originating from the sensors (42) and from the interface, and performing the fusion of the data provided by the digitized map and the information arising from the sensors and from the interface, and then calculating on the basis of these data the absolute location of the person on the map and correcting the position estimation errors.

Abstract: Angiogenesis, the formation of new blood vessels, is an integral part of normal physiological and developmental processes as well as several pathologies, ranging from tumor growth and metastasis to inflammation and ocular disease. Methods and compositions are provided for controlling normal angiogenesis and for treating angiogenesis associated or mediated diseases as well as for preventing cancer progression and metastasis through the use of a prostrate secretory protein (PSP) family member.

Abstract: Matrix metalloproteinases (MMPs) play an important role in morphogenesis, angiogenesis, wound healing, and in certain disorders such as rheumatoid arthritis, tumor invasion and metastasis. MMPs are thought to be regulated by a variety of cytokines, growth factors, hormones and phorbol esters. This regulation occurs on three levels; alteration of gene expression, activation of the latent zymogen and inhibition by the tissue inhibitors of metalloproteinases (TIMP). We report here a new agent that regulates the level of MMPs.

Abstract: Matrix metalloproteinases (MMPs) play an important role in morphogenesis, angiogenesis, wound healing, and in certain disorders such as rheumatoid arthritis, tumor invasion and metastasis. MMPs are thought to be regulated by a variety of cytokines, growth factors, hormones and phorbol esters. This regulation occurs on three levels; alteration of gene expression, activation of the latent zymogen and inhibition by the tissue inhibitors of metalloproteinases (TIMP). We report here a new agent that regulates the level of MMPs.

Abstract: Angiogenesis, the formation of new blood vessels, is an integral part of normal physiological and developmental processes as well as several pathologies, ranging from tumor growth and metastasis to inflammation and ocular disease. Methods and compositions are provided for controlling normal angiogenesis and for treating angiogenesis associated or mediated diseases.