Patents by Inventor Sylvie Rival

Sylvie Rival has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Position-independent and tissue specific expression of a transgene in milk of transgenic animals
    Patent number: 7511126
    Abstract: The present invention relates to an isolated insulator DNA molecule consisting of the 5? and 3? regions of the porcine wrap gene locus and a method for insulating the expression of an introduced heterologous gene from silencing and variegation effect in chromatin into which the gene has integrated. The invention is also directed to mammalian cells comprising said insulator DNA molecule and non human animals obtained therefrom, which are preferably able to express a polypeptide of interest in milk.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: March 31, 2009
    Assignee: Institut National de la Recherche Agronomique
    Inventors: Sylvie Rival, Celine Viglietta, Joe Attal, Louis-Marie Houdebine
  • Position-independent and tissue specific expression of a transgene in milk of transgenic animals
    Publication number: 20040265806
    Abstract: The present invention relates to an isolated insulator DNA molecule consisting of the 5′ and 3′ regions of the porcine wrap gene locus and a method for insulating the expression of an introduced heterologous gene from silencing and variegation effect in chromatin into which the gene has integrated. The invention is also directed to mammalian cells comprising said insulator DNA molecule and non human animals obtained therefrom, which are preferably able to express a polypeptide of interest in milk.
    Type: Application
    Filed: June 23, 2003
    Publication date: December 30, 2004
    Inventors: Sylvie Rival, Celine Viglietta, Joe Attal, Louis-Marie Houdebine