Patents by Inventor Sylvie Sim

Sylvie Sim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lacrimal implants and related methods
    Patent number: 11951038
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: April 9, 2024
    Assignee: Mati Therapeutics Inc.
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • LACRIMAL IMPLANTS AND RELATED METHODS
    Publication number: 20200030144
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Application
    Filed: October 7, 2019
    Publication date: January 30, 2020
    Applicant: Mati Therapeutics Inc.
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • Lacrimal implants and related methods
    Patent number: 10434009
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: October 8, 2019
    Assignee: Mati Therapeutics Inc.
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • Composite Lacrimal Insert and Related Methods
    Publication number: 20180008751
    Abstract: Lacrimal implants, methods of making lacrimal implants, and methods of treating ocular, respiration or other diseases or disorders using lacrimal implants are disclosed.
    Type: Application
    Filed: September 18, 2017
    Publication date: January 11, 2018
    Applicant: Mati Therapeutics Inc.
    Inventors: Sylvie Sim, Rachna Jain, Kathleen Farinas
  • LACRIMAL IMPLANTS AND RELATED METHODS
    Publication number: 20180000642
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Application
    Filed: September 18, 2017
    Publication date: January 4, 2018
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • Lacrimal implants and related methods
    Patent number: 9763824
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: September 19, 2017
    Assignee: Mati Therapeutics Inc.
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • Composite lacrimal insert and related methods
    Patent number: 9764066
    Abstract: Lacrimal implants, methods of making lacrimal implants, and methods of treating ocular, respiration or other diseases or disorders using lacrimal implants are disclosed.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: September 19, 2017
    Assignee: Mati Therapeutics Inc.
    Inventors: Sylvie Sim, Rachna Jain, Kathleen Farinas
  • LACRIMAL IMPLANTS AND RELATED METHODS
    Publication number: 20160361199
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Application
    Filed: August 25, 2016
    Publication date: December 15, 2016
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • Lacrimal implants and related methods
    Patent number: 9445944
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: September 20, 2016
    Assignee: Mati Therapeutics Inc.
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • Composite Lacrimal Insert and Related Methods
    Publication number: 20150367037
    Abstract: Lacrimal implants, methods of making lacrimal implants, and methods of treating ocular, respiration or other diseases or disorders using lacrimal implants are disclosed.
    Type: Application
    Filed: August 21, 2015
    Publication date: December 24, 2015
    Applicant: Mati Therapeutics Inc.
    Inventors: Sylvie Sim, Rachna Jain, Kathleen Farinas
  • Composite lacrimal insert and related methods
    Patent number: 9132088
    Abstract: Lacrimal implants, methods of making lacrimal implants, and methods of treating ocular, respiration or other diseases or disorders using lacrimal implants are disclosed.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: September 15, 2015
    Assignee: Mati Therapeutics Inc.
    Inventors: Sylvie Sim, Rachna Jain, Kathleen Farinas
  • LACRIMAL IMPLANTS AND RELATED METHODS
    Publication number: 20140180253
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Application
    Filed: February 28, 2014
    Publication date: June 26, 2014
    Applicant: Mati Therapeutics Inc.
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • Lacrimal implants and related methods
    Patent number: 8702643
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: April 22, 2014
    Assignee: Mati Therapeutics, Inc.
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • LACRIMAL IMPLANTS AND RELATED METHODS
    Publication number: 20120318281
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Application
    Filed: August 29, 2012
    Publication date: December 20, 2012
    Applicant: QLT INC
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • Lacrimal implants and related methods
    Patent number: 8333726
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: December 18, 2012
    Assignee: QLT Inc.
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • LACRIMAL IMPLANT BODY INCLUDING COMFORTING AGENT
    Publication number: 20100274224
    Abstract: Lacrimal implants for treating ocular diseases are disclosed. More particularly, lacrimal punctal plugs, methods of making such plugs, and methods of treating ocular diseases using such plugs are disclosed.
    Type: Application
    Filed: July 8, 2009
    Publication date: October 28, 2010
    Applicant: QLT Plug Delivery, Inc.
    Inventors: Rachna Jain, Robert W. Shimizu, Alan R. Rapacki, Sylvie Sim
  • SUSTAINED RELEASE DELIVERY OF ONE OR MORE AGENTS
    Publication number: 20100209477
    Abstract: The lacrimal implant delivery systems and methods described herein provide for controlled release of a therapeutic agent for the treatment of disease, including the treatment of glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agents. Treatment of disease, including glaucoma, ocular hypertension, or elevated intraocular pressure with latanoprost or other anti-glaucoma agent in conjunction with penetration enhancer, such as benzalkonium chloride, and/or artificial tears is also provided.
    Type: Application
    Filed: January 22, 2010
    Publication date: August 19, 2010
    Applicant: QLT PLUG DELIVERY INC.
    Inventors: ZUHAL BUTUNER, Deepank Utkhede, Sylvie Sim, David J. Wiseman
  • COMPOSITE LACRIMAL INSERT AND RELATED METHODS
    Publication number: 20100034870
    Abstract: Lacrimal implants, methods of making lacrimal implants, and methods of treating ocular, respiration or other diseases or disorders using lacrimal implants are disclosed.
    Type: Application
    Filed: April 29, 2009
    Publication date: February 11, 2010
    Applicant: QLT. Plug Delivery, Inc.
    Inventors: Sylvie Sim, Rachna Jain, Kathleen Farinas
  • Lacrimal implants and related methods
    Publication number: 20090104248
    Abstract: Lacrimal implants for treating diseases or disorders are disclosed. More particularly, lacrimal implants, methods of making such implants, and methods of treating ocular, respiration, inner ear or other diseases or disorders using such implants are disclosed.
    Type: Application
    Filed: September 8, 2008
    Publication date: April 23, 2009
    Applicant: QLT Plug Delivery, Inc. -QPDI
    Inventors: Alan R. Rapacki, Valery Rubinchik, John B. Holds, Sylvie Sim, Danny Shen
  • GENERATION OF NITRIC OXIDE IN SITU AT SUBSTRATE/BLOOD INTERFACES AND REPRODUCIBLE NITRIC OXIDE SENSOR FOR DETECTING NITROSOTHIOLS
    Publication number: 20080226686
    Abstract: A material includes a surface and a reactive agent that is located at the surface of the material, covalently attached to a backbone of the material, and/or located within the material. The reactive agent has nitrite reductase activity, nitrate reductase activity, and/or nitrosothiol reductase activity. The reactive agent also converts at least one of nitrites, nitrates and nitrosothiols to nitric oxide when in contact with blood. A reproducible nitrosothiol sensor is also disclosed.
    Type: Application
    Filed: November 21, 2007
    Publication date: September 18, 2008
    Inventors: Mark E. Meyerhoff, Melissa M. Reynolds, Bong K. Oh, Wansik Cha, Megan Frost, Sangyeul Hwang, Sylvie Sim, Yiduo Wu