Patents by Inventor Sylvie Victorine Lucienne Fournel

Sylvie Victorine Lucienne Fournel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8357654
    Abstract: A compound of formula (I) is described, wherein Y represents a macrocycle, the ring of which has 9 to 36 atoms, and is functionalized by three amine or COOH functions; Rc represents a group of formula H—Xa—Xb—Xc—Xd—Xe—(Xf)i—, i represents 0 or 1, Xa is in particular lysine, arginine, or ornithine residues, Xb is in particular glycine, asparagine, L-proline or D-proline residues, Xc and Xd are in particular tyrosine, phenylalanine or 3-nitrotyrosine residues, Xe and Xf are in particular amino acid residues: NH2—(CH2)n—COOH, n ranging from 1 to 10, or NH2—(CH2—CH2—O)m—CH2CH2COOH, m ranging from 3 to 6, provided that at least one of the amino acid residues Xa, Xb, Xc and Xd is different from the corresponding amino acid in the sequence of the natural CD40 143Lys-Gly-Tyr-Tyr146 fragment(SEQ ID NO: 1).
    Type: Grant
    Filed: December 15, 2005
    Date of Patent: January 22, 2013
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Gilles Guichard, Sylvie Victorine Lucienne Fournel, Olivier Chaloin, Nathalie Trouche, Sêbastien Wieckowski, Johan Hoebeke
  • Publication number: 20100183642
    Abstract: The invention concerns a compound of formula (I), wherein Y represents a macrocycle whereof the cycle comprises 9 to 36 atoms, and is functionalized by three amine or COOH functions; Rc represents a group of formula H—Xa—Xb—Xc—Xd—Xe—(Xf)i—, wherein i represents 0 or 1, Xn is in particular selected among lysine, arginine, ornithine residues, Xb is in particular selected among glycine, asparagine, L-proline or D-proline residues, Xc et Xd are in particular selected among tyrosine, phenylalanine or 3-nitrotyrosine residues, Xe et Xf are in particular selected among the following amino acid residues: NH2—(CH2)n—COOH, n ranging from 1 to 10 or NH2—(CH2—CH2—O)m—CH2CH2COOH, m ranging from 3 to 6, provided that one at least of the amino acid residues Xa, Xb, Xc and Xd is different from the corresponding amino acid in the sequence of the natural CD40 143Lys-Gly-Tyr-Tyr146 fragment
    Type: Application
    Filed: December 15, 2005
    Publication date: July 22, 2010
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Gilles Guichard, Sylvie Victorine Lucienne Fournel, Olivier Chaloin, Nathalie Trouche, Sebastien Wieckowski, Johan Hoebeke
  • Patent number: 7741280
    Abstract: The invention relates to a multimeric molecule which can imitate a natural multimeric proteinaceous ligand. The invention also relates to a multimeric molecule as defined above which is characterised in that it has the following general formula: A-Xn, wherein: n is equal to 3, 4, 5 or 6; A denotes a chemical group which is functionalised by at least three amine functions or COOH functions; and X denotes a D, B-D or B(D)-D? group, in which B is a spacer and D and D? are peptides or pseudopeptides corresponding to a sequence which is derived from the ligand and selected from residual matter forming the interface with the receptor and which can interact with the receptor.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: June 22, 2010
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Gilles François Roger Guichard, Sylvie Victorine Lucienne Fournel, Alberto Bianco, Johan Félicien Heobeke, Sylviane Muller
  • Publication number: 20060035839
    Abstract: The invention relates to a multimeric molecule which can imitate a natural multimeric proteinaceous ligand. The invention also relates to a multimeric molecule as defined above which is characterised in that it has the following general formula: A-Xn, wherein: n is equal to 3, 4, 5 or 6; A denotes a chemical group which is functionalised by at least three amine functions or COOH functions; and X denotes a D, B-D or B(D)-D? group, in which B is a spacer and D and D? are peptides or pseudopeptides corresponding to a sequence which is derived from the ligand and selected from residual matter forming the interface with the receptor and which can interact with the receptor.
    Type: Application
    Filed: May 28, 2003
    Publication date: February 16, 2006
    Inventors: Gilles Francois Guichard, Sylvie Victorine Lucienne Fournel, Alberto Bianco, Johan Heobeke, Sylviane Muller