Patents by Inventor Sylvine Deprele

Sylvine Deprele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bis-H-phosphinic acid derivatives as precursors to therapeutic bisphosphonates and uses thereof
    Patent number: 6781011
    Abstract: A novel class of compounds, i.e., 1,1-bis-H-phosphinates (or 1,1-bis-H-phosphinic acid derivatives) are provided. Also provided are novel methods for producing 1,1-bis-H-phosphinates and 1,1-bis-H-phosphinate conjugates. These compounds and conjugates are used are precursors of bisphosphonates and bisphosphonate conjugates, respectively, or as prodrugs directly for treating bone-related and various other diseases.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: August 24, 2004
    Assignee: Texas Christian University
    Inventors: Jean-Luc Montchamp, Sylvine Deprele
  • BIS-H-PHOSPHINIC ACID DERIVATIVES AS PRECURSORS TO THERAPEUTIC BISPHOSPHONATES AND USES THEREOF
    Publication number: 20040116673
    Abstract: A novel class of compounds, i.e., 1,1-bis-H-phosphinates (or 1,1-bis-H-phosphinic acid derivatives) are provided. Also provided are novel methods for producing 1,1-bis-H-phosphinates and 1,1-bis-H-phosphinate conjugates. These compounds and conjugates are used as precursors of bisphosphonates and bisphosphonate conjugates, respectively, or as prodrugs directly for treating bone-related and various other diseases.
    Type: Application
    Filed: December 13, 2002
    Publication date: June 17, 2004
    Applicant: Texas Christian University
    Inventors: Jean-Luc Montchamp, Sylvine Deprele