Patents by Inventor Synne LARSEN
Synne LARSEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11851514Abstract: This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.Type: GrantFiled: August 27, 2021Date of Patent: December 26, 2023Assignee: Life Technologies ASInventors: Geir Fonnum, Nils Pontus Lundberg, Muhammed Talha Gokmen, Synne Larsen, Wilhelm Glomm, Heidi Johnsen, Ruth Schmid, Lars Kilaas
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Publication number: 20220056184Abstract: This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.Type: ApplicationFiled: August 27, 2021Publication date: February 24, 2022Inventors: Geir Fonnum, Nils Pontus Lundberg, Muhammed Talha Gokmen, Synne Larsen, Wilhelm Glomm, Heidi Johnsen, Ruth Schmid, Lars Kilaas
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Patent number: 11130833Abstract: This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.Type: GrantFiled: October 8, 2020Date of Patent: September 28, 2021Assignee: LIFE TECHNOLOGIES ASInventors: Geir Fonnum, Nils Pontus Lundberg, Muhammed Talha Gokmen, Synne Larsen, Wilhelm Glomm, Heidi Johnsen, Ruth Schmid, Lars Kilaas
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Publication number: 20210139626Abstract: This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.Type: ApplicationFiled: October 8, 2020Publication date: May 13, 2021Inventors: Geir FONNUM, Nils Pontus LUNDBERG, Muhammed Talha GOKMEN, Synne LARSEN, Wilhelm Glomm, Heidi Johnsen, Ruth SCHMID, Lars Kilaas
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Patent number: 10836854Abstract: This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.Type: GrantFiled: July 19, 2016Date of Patent: November 17, 2020Assignees: SINTEF, LIFE TECHNOLOGIES ASInventors: Geir Fonnum, Nils Pontus Lundberg, Muhammed Talha Gokmen, Synne Larsen, Wilhelm Glomm, Heidi Johnsen, Ruth Schmid, Lars Kilaas
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Patent number: 10676790Abstract: A polymer substrate, such as a polymer coating or a polymer hydrogel network, includes carboxyl moieties that can be used as conjugation sites to which receptor or analyte molecules can be attached. In an example, the polymer substrate includes a polyacrylamide polymer network having alkanoic acid moieties or derivatives thereof, which can react with carboxyl activating compounds to provide an activated alkanoate moieties on the polyacrylamide network. Amine-terminated nucleic acids can react with the activated alkanoate moieties to capture the nucleic acid to the polymer network through an alkylamide moiety.Type: GrantFiled: November 30, 2018Date of Patent: June 9, 2020Assignees: LIFE TECHNOLOGIES CORPORATION, LIFE TECHNOLOGIES ASInventors: Geir Fonnum, Steven M. Menchen, Alfred Lui, Guobing Xiang, Synne Larsen
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Publication number: 20190390018Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.Type: ApplicationFiled: January 21, 2019Publication date: December 26, 2019Inventors: Geir FONNUM, Steven M. MENCHEN, M. Talha GOKMEN, Pontus LUNDBERG, Prasanna Krishnan THWAR, Alfred LUI, Lily LU, Wolfgang HINZ, Lene HUSABOE, Elisabeth BREIVOLD, Astrid Evenroed MOLTEBERG, Synne LARSEN
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Publication number: 20190177787Abstract: A polymer substrate, such as a polymer coating or a polymer hydrogel network, includes carboxyl moieties that can be used as conjugation sites to which receptor or analyte molecules can be attached. In an example, the polymer substrate includes a polyacrylamide polymer network having alkanoic acid moieties or derivatives thereof, which can react with carboxyl activating compounds to provide an activated alkanoate moieties on the polyacrylamide network Amine-terminated nucleic acids can react with the activated alkanoate moieties to capture the nucleic acid to the polymer network through an alkylamide moiety.Type: ApplicationFiled: November 30, 2018Publication date: June 13, 2019Inventors: Geir FONNUM, Steven M. MENCHEN, Alfred LUI, Guobing XIANG, Synne LARSEN
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Patent number: 10189956Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.Type: GrantFiled: January 15, 2018Date of Patent: January 29, 2019Assignees: LIFE TECHNOLOGIES AS, LIFE TECHNOLOGIES CORPORATIONInventors: Geir Fonnum, Steven M. Menchen, M. Talha Gokmen, Pontus Lundberg, Prasanna Krishnan Thwar, Alfred Lui, Lily Lu, Wolfgang Hinz, Lene Husaboe, Elisabeth Breivold, Astrid Evenroed Molteberg, Synne Larsen
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Patent number: 10144968Abstract: A polymer substrate, such as a polymer coating or a polymer hydrogel network, includes carboxyl moieties that can be used as conjugation sites to which receptor or analyte molecules can be attached. In an example, the polymer substrate includes a polyacrylamide polymer network having alkanoic acid moieties or derivatives thereof, which can react with carboxyl activating compounds to provide an activated alkanoate moieties on the polyacrylamide network. Amine-terminated nucleic acids can react with the activated alkanoate moieties to capture the nucleic acid to the polymer network through an alkylamide moiety.Type: GrantFiled: July 1, 2016Date of Patent: December 4, 2018Assignees: LIFE TECHNOLOGIES CORPORATION, LIFE TECHNOLOGIES ASInventors: Geir Fonnum, Steven M. Menchen, Alfred Lui, Guobing Xiang, Synne Larsen
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Publication number: 20180237595Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.Type: ApplicationFiled: January 15, 2018Publication date: August 23, 2018Inventors: Geir FONNUM, Steven M. MENCHEN, M. Talha GOKMEN, Pontus LUNDBERG, Prasanna Krishnan THWAR, Alfred LUI, Lily LU, Wolfgang HINZ, Lene Husaboe, Elisabeth BREIVOLD, Astrid Evenroed MOLTEBERG, Synne LARSEN
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Publication number: 20180215852Abstract: This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.Type: ApplicationFiled: July 19, 2016Publication date: August 2, 2018Applicant: SINTEFInventors: Geir FONNUM, Nils LUNDBERG, Muhammed GOKMEN, Synne LARSEN, Wilhelm Glomm, Heidi Johnsen, Ruth SCHMID, Lars Kilaas
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Patent number: 9868826Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.Type: GrantFiled: July 1, 2016Date of Patent: January 16, 2018Assignees: Life Technologies Corporation, Life Technologies ASInventors: Geir Fonnum, Steven M. Menchen, Talha M. Gokmen, Pontus Lundberg, Prasanna Krishnan Thwar, Alfred Lui, Lily Lu, Wolfgang Hinz, Lene Husaboe, Elisabeth Breivold, Astrid Evenroed Molteberg, Synne Larsen
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Publication number: 20170002410Abstract: A polymer substrate, such as a polymer coating or a polymer hydrogel network, includes carboxyl moieties that can be used as conjugation sites to which receptor or analyte molecules can be attached. In an example, the polymer substrate includes a polyacrylamide polymer network having alkanoic acid moieties or derivatives thereof, which can react with carboxyl activating compounds to provide an activated alkanoate moieties on the polyacrylamide network Amine-terminated nucleic acids can react with the activated alkanoate moieties to capture the nucleic acid to the polymer network through an alkylamide moiety.Type: ApplicationFiled: July 1, 2016Publication date: January 5, 2017Inventors: Geir Fonnum, Steven M. Menchen, Alfred Lui, Guobing Xiang, Synne Larsen
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Publication number: 20170002152Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.Type: ApplicationFiled: July 1, 2016Publication date: January 5, 2017Inventors: Geir FONNUM, Steven M. MENCHEN, Talha M. GOKMEN, Pontus LUNDBERG, Prasanna Krishnan THWAR, Alfred LUI, Lily LU, Wolfgang HINZ, Lene HUSABOE, Elisabeth BREIVOLD, Astrid Evenroed MOLTEBERG, Synne LARSEN