Patents by Inventor Szabolcs SEMSEY

Szabolcs SEMSEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATING & PREVENTING E COLI INFECTIONS
    Publication number: 20250049895
    Abstract: The invention relates to methods and compositions for treating or preventing an infection by E coli cells in human or animal subjects. The method comprises administering to the subject a plurality of transduction particles that encode a nuclease for targeting the genomes of B2 phylogroup E coli cells.
    Type: Application
    Filed: July 19, 2024
    Publication date: February 13, 2025
    Applicant: SNIPR Biome ApS
    Inventors: Jakob Krause HAABER, Szabolcs SEMSEY, Mette GROVE, Birgitte DAMHOLT, Dziuginta JASINSKYTE, Yilmaz Emre GENÇAY
  • TRANSMISSIBLE ELEMENTS COMPRISING PATHWAY MODIFICATION SYSTEMS AND EXOGENOUS NUCLEIC ACIDS FOR THE PRODUCTION OF MOLECULES OF INTEREST
    Publication number: 20250043291
    Abstract: The present invention relates to transmissible elements (e.g. conjugative plasmids, phage and phagemid) which are engineered to express molecules of interest (MOIs) and a pathway modification system (PMS) which is able to introduce mutations in target endogenous genes in a recipient bacterium, or is able to produce nucleic acids which inhibit or increase expression of target endogenous genes in a recipient bacterium, or is able to express peptide inhibitor molecules which inhibit a target endogenous protein in a recipient bacterium. The invention relates to host cells containing the transmissible elements, to pharmaceutical compositions containing such transmissible elements or host cells, and their use in the treatment of various diseases.
    Type: Application
    Filed: July 3, 2024
    Publication date: February 6, 2025
    Inventors: Jennifer LE MIÈRE, Emilie SØNDBERG, Szabolcs SEMSEY, Ioannis MOUGIAKOS
  • NOVEL TYPE OF CRISPR/CAS SYSTEM
    Publication number: 20250002942
    Abstract: The technology described herein relates to new CRISPR/Cas systems and components thereof, vectors, proteins, fusion proteins, ribonucleoprotein complexes and methods of using the new system and components. The new system can be used in CRISPRi applications and can be fused to any number of effector domain modalities, such as nucleases, base editors, prime editors and the like to perform various DNA modifications.
    Type: Application
    Filed: June 25, 2024
    Publication date: January 2, 2025
    Inventors: Szabolcs SEMSEY, Ioannis MOUGIAKOS, Emilie SØNDBERG, Jasper CLUBE
  • MICROBIOTA ENGINEERING
    Publication number: 20240384279
    Abstract: The invention relates to methods and means for temporally regulating the production of products of interest (eg, proteins or RNAs) in microbiota of subjects, such as gut microbiota of humans or animals.
    Type: Application
    Filed: August 1, 2022
    Publication date: November 21, 2024
    Inventors: Christian MUNCK, Andreas PORSE, Jakob KRAUSE HAABER, Lev KOVAL, Lauge ALFASTSEN, Szabolcs SEMSEY
  • Treating and preventing infections
    Patent number: 12076375
    Abstract: The invention relates to methods and compositions for treating or preventing an infection by E coli cells in human or animal subjects. The method comprises administering to the subject a plurality of transduction particles that encode a nuclease for targeting the genomes of B2 phylogroup E coli cells.
    Type: Grant
    Filed: July 13, 2022
    Date of Patent: September 3, 2024
    Assignee: SNIPR BIOME APS
    Inventors: Jakob Krause Haaber, Szabolcs Semsey, Mette Grove, Birgitte Damholt, Dziuginta Jasinskyte, Yilmaz Emre Gençay
  • TREATING & PREVENTING E COLI INFECTIONS
    Publication number: 20220387559
    Abstract: The invention relates to methods and compositions for treating or preventing an infection by E coli cells in human or animal subjects. The method comprises administering to the subject a plurality of transduction particles that encode a nuclease for targeting the genomes of B2 phylogroup E coli cells.
    Type: Application
    Filed: July 13, 2022
    Publication date: December 8, 2022
    Inventors: Jakob Krause HAABER, Szabolcs SEMSEY, Metteq GROVE, Birgitte DAMHOLT, Dziuginta JIASINSKYTE, Yilmaz GENÇAY