Abstract: The present disclosure relates to a body fluid collection device (1), the body fluid collection device (1) comprises a tube body (10), wherein the tube body (10) is used to contain the collected body fluid and is provided with an opened end (12); a tube plug (20), wherein the tube plug (20) is configured to be able to hermetically close the opened end (12) of the tube body (10); and a filter (30), wherein the filter (30) is arranged in the tube body (10) for filtering out specific components from a body fluid to be collected, wherein the filter (30) is configured to be capable of being attached to the tube plug (20) at the open end, and the tube plug (20) is hermetically connected to the filter (30).