Patents by Inventor Szu-Yi Chou

Szu-Yi Chou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7485438
    Abstract: Embodiments of the invention generally provide methods and compositions for producing polyvalent antigens. In one aspect, the invention provides a method for producing a cross-linked antigen. In another aspect, the invention provides a method of using cross-linked products as antigens to immunize animals and induce strong immune responses.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: February 3, 2009
    Inventor: Szu-Yi Chou
  • Patent number: 7101695
    Abstract: Embodiments of the invention generally provide methods and compositions for producing recombinant transglutaminases. The purified recombinant transglutaminases of the invention are reactive to a broad range of compounds and exhibit broad substrate activity. In one embodiment, Streptoverticillium mobaraense (ATCC 29032), and Streptoverticillium cinnamoneum (ATCC 11874) recombinant transglutaminase fusion proteins purified from E. coli are provided to a better yield, higher purity, and activity than hitherto possible by recombinant DNA technology.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: September 5, 2006
    Inventor: Szu-Yi Chou
  • Publication number: 20040005654
    Abstract: Embodiments of the invention generally provide methods and compositions for producing polyvalent antigens. In one aspect, the invention provides a method for producing a cross-linked antigen. In another aspect, the invention provides a method of using cross-linked products as antigens to immunize animals and induce strong immune responses.
    Type: Application
    Filed: August 28, 2002
    Publication date: January 8, 2004
    Inventor: Szu-Yi Chou
  • Publication number: 20040001848
    Abstract: Embodiments of the invention generally provide methods and compositions for producing disease-specific antigens. In one aspect, the invention provides a method of producing an antigen specific for Alzheimer's disease. In another aspect, the invention provides a method of producing a polyvalent antigen for two or more diseases. In yet another aspect, compositions of antigens are prepared and provided to immunize animals and induce strong immune responses.
    Type: Application
    Filed: August 28, 2002
    Publication date: January 1, 2004
    Inventor: Szu-Yi Chou
  • Publication number: 20030224476
    Abstract: A method for producing transglutaminase-reactive compounds is provided. In one aspect, transglutaminase reactivity of a compound is enhanced. In another aspect, transglutaminase non-reactive compounds are modified to be reactive with transglutaminase.
    Type: Application
    Filed: August 28, 2002
    Publication date: December 4, 2003
    Inventor: Szu-Yi Chou
  • Publication number: 20030219853
    Abstract: The invention provides a method of producing a cross-linked compound by a biological agent. In one aspect, cross-linking a compound requires a change of color in the cross-linking reaction mixture. In another aspect, attaching one or more amino acid residues to the compound is also required. In yet another aspect, the compound is obtained, and denaturing the compound in the presence of a denaturant and refolding the compound are performed before cross-linking the compound by a solution of the biological agent.
    Type: Application
    Filed: August 28, 2002
    Publication date: November 27, 2003
    Inventor: Szu-Yi Chou
  • Publication number: 20030219857
    Abstract: Embodiments of the invention generally provide methods and compositions for producing recombinant transglutaminases. The purified recombinant transglutaminases of the invention are reactive to a broad range of compounds and exhibit broad substrate activity. In one embodiment, Streptoverticillium mobaraense (ATCC 29032), and Streptoverticillium cinnamoneum (ATCC 11874) recombinant transglutaminase fusion proteins purified from E. coli are provided to a better yield, higher purity, and activity than hitherto possible by recombinant DNA technology.
    Type: Application
    Filed: August 28, 2002
    Publication date: November 27, 2003
    Inventor: Szu-Yi Chou