Patents by Inventor Szu-Yuan LEE

Szu-Yuan LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USES OF HYALURONAN CONJUGATES
    Publication number: 20240415973
    Abstract: Disclosed herein is a method of using a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. The hyaluronan conjugates are used in treating neurodegenerative diseases.
    Type: Application
    Filed: August 28, 2024
    Publication date: December 19, 2024
    Applicant: Aihol Corporation
    Inventors: Szu-Yuan LEE, Ping-Shan LAI, Chih-An LIN
  • Hyaluronan conjugates and uses thereof
    Patent number: 12128108
    Abstract: Disclosed herein is a method of using a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. The hyaluronan conjugates are used in treating neurodegenerative diseases.
    Type: Grant
    Filed: November 2, 2022
    Date of Patent: October 29, 2024
    Assignee: Aihol Corporation
    Inventors: Szu-Yuan Lee, Ping-Shan Lai, Chih-An Lin
  • HYALURONAN CONJUGATES AND USES THEREOF
    Publication number: 20230080473
    Abstract: Disclosed herein is a method of using a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. The hyaluronan conjugates are used in treating neurodegenerative diseases.
    Type: Application
    Filed: November 2, 2022
    Publication date: March 16, 2023
    Applicant: Aihol Corporation
    Inventors: Szu-Yuan LEE, Ping-Shan LAI, Chih-An LIN
  • Hyaluronan conjugates and uses thereof
    Patent number: 11524079
    Abstract: Disclosed herein is a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. Also disclosed herein are the uses of the hyaluronan conjugate in treating or preventing neurodegenerative diseases.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: December 13, 2022
    Assignee: AIHOL CORPORATION
    Inventors: Szu-Yuan Lee, Ping-Shan Lai, Chih-An Lin
  • Method for improving substitution rate and/or substitution efficiency of hyaluronan-drug conjugates
    Patent number: 11458204
    Abstract: Disclosed herein is a method for preparing a hyaluronan-drug conjugate. The method uses the ethyl cyano(hydroxyimino)acetate/diisopropylcarbodiimide coupling system in a homogeneous reaction phase, which unexpectedly improves the substitution rate and substitution efficiency of hyaluronan-drug conjugates for various drugs.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: October 4, 2022
    Assignee: Aihol Corporation
    Inventors: Szu-Yuan Lee, Ping-Shan Lai, Chih-An Lin
  • METHOD FOR IMPROVING SUBSTITUTION RATE AND/OR SUBSTITUTION EFFICIENCY OF HYALURONAN-DRUG CONJUGATES
    Publication number: 20210369852
    Abstract: Disclosed herein is a method for preparing a hyaluronan-drug conjugate. The method uses the ethyl cyano(hydroxyimino)acetate/diisopropylcarbodiimide coupling system in a homogeneous reaction phase, which unexpectedly improves the substitution rate and substitution efficiency of hyaluronan-drug conjugates for various drugs.
    Type: Application
    Filed: December 10, 2020
    Publication date: December 2, 2021
    Applicant: Aihol Corporation
    Inventors: Szu-Yuan LEE, Ping-Shan LAI, Chih-An LIN
  • HYALURONAN CONJUGATES AND USES THEREOF
    Publication number: 20200376132
    Abstract: Disclosed herein is a hyaluronan conjugate, which includes a hyaluronic acid (HA), a sex hormone, and a linker for coupling one of the disaccharide units of the HA and the sex hormone. Also disclosed herein are the uses of the hyaluronan conjugate in treating or preventing neurodegenerative diseases.
    Type: Application
    Filed: June 2, 2020
    Publication date: December 3, 2020
    Applicant: Aihol Corporation
    Inventors: Szu-Yuan LEE, Ping-Shan LAI, Chih-An LIN