Abstract: A loader coupler includes left and right spaced-apart inner rib mounts including inner mount pins connected to a body, and left and right inner locking regions aligned with the left and right inner rib mounts. The coupler includes left and right spaced-apart outer rib mounts including outer mount pins connected to the body, and left and right outer locking regions aligned with the left and right outer rib mounts. The coupler includes a lock system including: (i) left and right first lock plungers that move between locked and unlocked positions relative to the left and right inner locking regions, respectively; and, (ii) left and right second lock plungers that move between locked and unlocked positions relative to the left and right outer locking regions, respectively. The left and right outer mount pins and/or the left and right inner mount pins are removable from the body.

Abstract: In one aspect, a current source is provided to limit noise and offset. In one embodiment, a source transistor is provided, with current sourced at the drain. A feedback network runs from the source node to the gate. The feedback network produces voltage gain by a transconductance, such as a transistor. Appropriate capacitors are also provided, and two pairs of switches are disposed to provide offset cancellation by toggling between gain and clamp modes in the switched capacitor architecture.

Abstract: In one example embodiment, a current source is provided to limit noise and offset. In one embodiment, a source transistor is provided, with current sourced at the drain. A feedback network runs from the source node to the gate. The feedback network produces voltage gain by a transconductance, such as a transistor. Appropriate capacitors are also provided, and two pairs of switches are disposed to provide offset cancellation by toggling between gain and clamp modes in the switched capacitor architecture.

Abstract: A multiplying analog-to-digital converter (“MDAC”) that reduces the power consumption of the MDAC by at least 2.3 times by improving the feedback factor. The amplifier may include a feed forward approach in which the input capacitor (also referred to as “sampling capacitor”) is buffered by a common gate amplifier to improve bandwidth by removing input and parasitic capacitance terms from the global feedback loss. THe amplifier may also use an alternate form of local compensation, for example, cascode compensation. The amplifier may also further include an alternate way to reduce parasitic capacitance with a buffer.

Abstract: One or more circuit elements such as silicon diodes, resistors, capacitors, and inductors are disposed between the semiconductor structure of a semiconductor light emitting device and the connection layers used to connect the device to an external structure. In some embodiments, the n-contacts to the semiconductor structure are distributed across multiple vias, which are isolated from the p-contacts by one or more dielectric layers. The circuit elements are formed in the contacts-dielectric layers-connection layers stack.

Abstract: A loader coupler includes left and right spaced-apart inner rib mounts including inner mount pins connected to a body, and left and right inner locking regions aligned with the left and right inner rib mounts. The coupler includes left and right spaced-apart outer rib mounts including outer mount pins connected to the body, and left and right outer locking regions aligned with the left and right outer rib mounts. The coupler includes a lock system including: (i) left and right first lock plungers that move between locked and unlocked positions relative to the left and right inner locking regions, respectively; and, (ii) left and right second lock plungers that move between locked and unlocked positions relative to the left and right outer locking regions, respectively. The left and right outer mount pins and/or the left and right inner mount pins are removable from the body.

Abstract: One or more circuit elements such as silicon diodes, resistors, capacitors, and inductors are disposed between the semiconductor structure of a semiconductor light emitting device and the connection layers used to connect the device to an external structure. In some embodiments, the n-contacts to the semiconductor structure are distributed across multiple vias, which are isolated from the p-contacts by one or more dielectric layers. The circuit elements are formed in the contacts-dielectric layers-connection layers stack.

Abstract: One or more circuit elements such as silicon diodes, resistors, capacitors, and inductors are disposed between the semiconductor structure of a semiconductor light emitting device and the connection layers used to connect the device to an external structure. In some embodiments, the n-contacts to the semiconductor structure are distributed across multiple vias, which are isolated from the p-contacts by one or more dielectric layers. The circuit elements are formed in the contacts-dielectric layers-connection layers stack.

Abstract: An electromagnet having at least one access port oriented perpendicularly to the electromagnet's central axis. The magnet has a conventional helical winding along its central axis. However, at some point along the length of the axis, the pitch of the helical winding is greatly increased in order to create a region with a comparatively low turn density. One or more ports are provided in this region. These ports provide access from the magnet's central bore to the magnet's exterior. A sample can be placed in the central bore near the ports. A beam traveling down the central bore, or through one of the radial ports, will strike the sample and be scattered in all directions. The ports allow access for instrumentation which is used to evaluate the scattered beam.

Abstract: A system has utility is guiding and tracking the execution of manual procedures. The system includes a support that holds multiple sample receptacles, computational circuitry to execute a protocol script that delivers instructions for executing various steps of the procedure, and a protocol progress sensor that advances the execution of the protocol script. The computer may be comparable in size to a support for holding the receptacles The receptacles be arranged in a frame, may be sealed with peelable or puncturable films and may include identifiers that are read by the system. The receptacles may be filled with a high heat capacity material to maintain a given temperature range. A variety of companion devices may interact with the system using the protocol script. An instrumented pipettor can communicate with the system for semi-automated execution of protocols.

Abstract: Devices and methods are provided for more efficiently performing electrophoresis and electroblotting. A sandwich structure includes an electrophoresis gel affixed to a blotting membrane. A gel casting and/or running frame is used to hold the sandwich. A method and composition that allows separation of the gel and membrane after performing a combined electrophoresis and electroblotting operation so as to allow further operations to be performed individually upon the membrane, gel or both. A uniform electrophoretic field may be created by surrounding the sandwich structure using an insulating fluid; the insulating fluid is then swapped for a conducting fluid to allow application of an electroblotting field. An apparatus automatically manages fluid exchange and actuation of electrophoresis and electroblotting electrodes. A plurality of parallel cavities may be used to hold multiple gels or gel membrane sandwiches.

Abstract: An electromagnet having at least one access port oriented perpendicularly to the electromagnet's central axis. The magnet has a conventional helical winding along its central axis. However, at some point along the length of the axis, the pitch of the helical winding is greatly increased in order to create a region with a comparatively low turn density. One or more ports are provided in this region. These ports provide access from the magnet's central bore to the magnet's exterior. A sample can be placed in the central bore near the ports. A beam traveling down the central bore, or through one of the radial ports, will strike the sample and be scattered in all directions. The ports allow access for instrumentation which is used to evaluate the scattered beam.

Abstract: The present invention pertains to devices comprising at least one purification unit, used to purify and/or concentrate a target molecule contained within a test sample. Typically, the target molecule in a test sample will be a nucleic acid. These purified nucleic acids can be used in a variety of ways, including being subjected to nucleotide sequence analysis. Methods of using the devices and kits containing the devices are also provided.